SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cd8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 5cd8 MATERNAL EFFECT
PROTEIN OSKAR
(Drosophila
melanogaster) 		3 / 3 ASP A 157
PHE A 198
ARG A 150
 None
 0.89A 2a3aA-5cd8A:
undetectable		 2a3aA-5cd8A:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 5cd8 MATERNAL EFFECT
PROTEIN OSKAR
(Drosophila
melanogaster) 		4 / 5 ILE A 156
ILE A 177
TYR A 181
GLU A 180
 None
 1.16A 4a99D-5cd8A:
undetectable		 4a99D-5cd8A:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_E_IPHE101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 5cd8 MATERNAL EFFECT
PROTEIN OSKAR
(Drosophila
melanogaster) 		4 / 7 ILE A 216
HIS A 167
LEU A 164
ALA A 168
 None
 0.95A 5hrqE-5cd8A:
undetectable
5hrqF-5cd8A:
undetectable
5hrqJ-5cd8A:
undetectable		 5hrqE-5cd8A:
12.64
5hrqF-5cd8A:
19.61
5hrqJ-5cd8A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8O_B_CHDB1001_0
(GASTROTROPIN)		 5cd8 MATERNAL EFFECT
PROTEIN OSKAR
(Drosophila
melanogaster) 		5 / 12 ILE A 177
PHE A 189
LEU A 200
VAL A 195
SER A 149
 None
 1.30A 5l8oB-5cd8A:
undetectable		 5l8oB-5cd8A:
23.97