SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cdc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5cdc VP1, STRUCTURAL
POLYPROTEIN
(Israeli
acute
paralysis
virus) 		4 / 7 ARG A  92
GLY A  91
SER A 166
PHE A 147
 None
 1.00A 2c8aB-5cdcA:
undetectable		 2c8aB-5cdcA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5cdc VP1, STRUCTURAL
POLYPROTEIN
(Israeli
acute
paralysis
virus) 		4 / 7 ARG A  92
GLY A  91
SER A 166
PHE A 147
 None
 1.06A 2c8aD-5cdcA:
undetectable		 2c8aD-5cdcA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 5cdc VP1, STRUCTURAL
POLYPROTEIN
(Israeli
acute
paralysis
virus) 		4 / 7 PRO A 135
TYR A 134
THR A 133
ILE A 132
 None
 0.78A 3p50A-5cdcA:
undetectable		 3p50A-5cdcA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 5cdc VP1, STRUCTURAL
POLYPROTEIN
(Israeli
acute
paralysis
virus) 		4 / 7 PRO A 135
TYR A 134
THR A 133
ILE A 132
 None
 0.78A 3p50B-5cdcA:
undetectable		 3p50B-5cdcA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 5cdc VP1, STRUCTURAL
POLYPROTEIN
(Israeli
acute
paralysis
virus) 		4 / 7 PRO A 135
TYR A 134
THR A 133
ILE A 132
 None
 0.78A 3p50C-5cdcA:
undetectable		 3p50C-5cdcA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_D_PFLD320_1
(GLR4197 PROTEIN)		 5cdc VP1, STRUCTURAL
POLYPROTEIN
(Israeli
acute
paralysis
virus) 		4 / 7 PRO A 135
TYR A 134
THR A 133
ILE A 132
 None
 0.78A 3p50D-5cdcA:
undetectable		 3p50D-5cdcA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 5cdc VP1, STRUCTURAL
POLYPROTEIN
(Israeli
acute
paralysis
virus) 		4 / 7 PRO A 135
TYR A 134
THR A 133
ILE A 132
 None
 0.77A 3p50E-5cdcA:
undetectable		 3p50E-5cdcA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 5cdc VP1, STRUCTURAL
POLYPROTEIN
(Israeli
acute
paralysis
virus) 		5 / 12 ASP A  76
ILE A 156
ASP A  71
ARG A 182
PHE A 188
 None
 1.32A 3phaB-5cdcA:
undetectable		 3phaB-5cdcA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5R_A_KANA2002_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 5cdc VP1, STRUCTURAL
POLYPROTEIN
(Israeli
acute
paralysis
virus) 		5 / 11 TYR A 148
ILE A 156
TYR A 164
PHE A 188
TYR A  88
 None
 1.35A 3q5rA-5cdcA:
undetectable		 3q5rA-5cdcA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W37_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5cdc VP1, STRUCTURAL
POLYPROTEIN
(Israeli
acute
paralysis
virus) 		5 / 12 ASP A  76
ALA A 183
ILE A 156
ASP A  71
PHE A 188
 None
 1.30A 3w37A-5cdcA:
undetectable		 3w37A-5cdcA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5cdc VP1, STRUCTURAL
POLYPROTEIN
(Israeli
acute
paralysis
virus) 		5 / 12 ASP A  76
ALA A 183
ILE A 156
ASP A  71
PHE A 188
 None
 1.32A 3welA-5cdcA:
undetectable		 3welA-5cdcA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEM_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5cdc VP1, STRUCTURAL
POLYPROTEIN
(Israeli
acute
paralysis
virus) 		5 / 12 ASP A  76
ALA A 183
ILE A 156
ASP A  71
PHE A 188
 None
 1.43A 3wemA-5cdcA:
undetectable		 3wemA-5cdcA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEN_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5cdc VP1, STRUCTURAL
POLYPROTEIN
(Israeli
acute
paralysis
virus) 		5 / 12 ASP A  76
ALA A 183
ILE A 156
ASP A  71
PHE A 188
 None
 1.41A 3wenA-5cdcA:
undetectable		 3wenA-5cdcA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5cdc VP1, STRUCTURAL
POLYPROTEIN
(Israeli
acute
paralysis
virus) 		5 / 12 ASP A  76
ALA A 183
ILE A 156
ASP A  71
PHE A 188
 None
 1.44A 3weoA-5cdcA:
undetectable		 3weoA-5cdcA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)		 5cdc VP1, STRUCTURAL
POLYPROTEIN
(Israeli
acute
paralysis
virus) 		5 / 12 ARG A 182
SER A  82
GLY A 184
PHE A 188
TYR A  94
 None
 1.25A 4r29A-5cdcA:
undetectable		 4r29A-5cdcA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN)		 5cdc VP1, STRUCTURAL
POLYPROTEIN
(Israeli
acute
paralysis
virus) 		5 / 12 ARG A 182
SER A  82
GLY A 184
PHE A 188
TYR A  94
 None
 1.22A 4r29B-5cdcA:
undetectable		 4r29B-5cdcA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 5cdc VP1, STRUCTURAL
POLYPROTEIN
(Israeli
acute
paralysis
virus) 		4 / 8 PRO A 135
TYR A 134
THR A 133
ILE A 132
 None
 0.80A 5mzrE-5cdcA:
undetectable		 5mzrE-5cdcA:
19.66