SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cdd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 5cdd STRUCTURAL
POLYPROTEIN, VP2
(Israeli
acute
paralysis
virus) 		4 / 8 THR C 221
PRO C 222
VAL C 223
ALA C 146
 None
 0.92A 2v32A-5cddC:
undetectable
2v32B-5cddC:
undetectable		 2v32A-5cddC:
20.33
2v32B-5cddC:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_0
(REPRESSOR PROTEIN
MPHR(A))		 5cdd STRUCTURAL
POLYPROTEIN, VP2
(Israeli
acute
paralysis
virus) 		5 / 12 GLY C 225
VAL C 145
LEU C 139
MET C 149
ILE C 237
 None
 1.03A 3frqB-5cddC:
undetectable		 3frqB-5cddC:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 5cdd STRUCTURAL
POLYPROTEIN, VP2
(Israeli
acute
paralysis
virus) 		3 / 3 ASN C 142
ALA C 141
LYS C 234
 None
 0.96A 3runA-5cddC:
undetectable		 3runA-5cddC:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OS7_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5cdd STRUCTURAL
POLYPROTEIN, VP2
(Israeli
acute
paralysis
virus) 		3 / 3 HIS C  61
SER C  62
LYS C  59
 None
 1.43A 5os7A-5cddC:
undetectable		 5os7A-5cddC:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GMD_B_ACTB402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5cdd STRUCTURAL
POLYPROTEIN, VP2
(Israeli
acute
paralysis
virus) 		3 / 3 HIS C  61
SER C  62
LYS C  59
 None
 1.43A 6gmdB-5cddC:
undetectable		 6gmdB-5cddC:
18.97