SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cdf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 5cdf ATP SYNTHASE SUBUNIT
BETA
(Paracoccus
denitrificans) 		5 / 12 ILE E 132
ASP E 136
LEU E 149
GLY E 131
LEU E 160
 None
 1.07A 1liiA-5cdfE:
undetectable		 1liiA-5cdfE:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_B_SAMB400_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 5cdf ATP SYNTHASE SUBUNIT
BETA
(Paracoccus
denitrificans) 		6 / 9 ALA E 179
VAL E 181
GLY E 216
ILE E 111
LEU E 230
ALA E 229
 None
 1.36A 2z0yB-5cdfE:
undetectable		 2z0yB-5cdfE:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 5cdf ATP SYNTHASE SUBUNIT
BETA
(Paracoccus
denitrificans) 		4 / 8 VAL E 214
VAL E 251
ILE E  77
GLY E 232
 None
 0.96A 3hjoA-5cdfE:
undetectable		 3hjoA-5cdfE:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_H_LFXH0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 5cdf ATP SYNTHASE SUBUNIT
BETA
(Paracoccus
denitrificans) 		4 / 6 ARG E 333
SER E 336
GLU E 183
GLU E 187
 None
 0.99A 3k9fA-5cdfE:
undetectable
3k9fB-5cdfE:
undetectable
3k9fD-5cdfE:
undetectable		 3k9fA-5cdfE:
21.56
3k9fB-5cdfE:
21.56
3k9fD-5cdfE:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_B_SAMB302_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 5cdf ATP SYNTHASE SUBUNIT
BETA
(Paracoccus
denitrificans) 		5 / 12 GLY E  82
GLY E 232
PHE E 178
LEU E 213
ALA E 236
 None
 1.04A 3kkzB-5cdfE:
undetectable		 3kkzB-5cdfE:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_A_REAA501_1
(RETINOIC ACID
RECEPTOR BETA)		 5cdf ATP SYNTHASE SUBUNIT
BETA
(Paracoccus
denitrificans) 		5 / 11 LEU E 149
LEU E 160
ILE E 161
LEU E 128
ILE E 135
 None
 1.05A 4dm8A-5cdfE:
undetectable		 4dm8A-5cdfE:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 5cdf ATP SYNTHASE SUBUNIT
BETA
(Paracoccus
denitrificans) 		4 / 8 ASP E 252
GLN E 217
MET E 226
VAL E 228
 None
 0.99A 4lnwA-5cdfE:
undetectable		 4lnwA-5cdfE:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5cdf ATP SYNTHASE SUBUNIT
BETA
(Paracoccus
denitrificans) 		5 / 12 GLU E  95
ASN E  91
ALA E 212
PHE E 239
VAL E 177
 None
 1.05A 4u8yB-5cdfE:
undetectable		 4u8yB-5cdfE:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 5cdf ATP SYNTHASE SUBUNIT
BETA
(Paracoccus
denitrificans) 		3 / 3 MET E  58
GLN E 217
TYR E 215
 None
 1.05A 4udcA-5cdfE:
undetectable		 4udcA-5cdfE:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 5cdf ATP SYNTHASE SUBUNIT
BETA
(Paracoccus
denitrificans) 		5 / 8 ASP E 446
ALA E 401
VAL E 400
LYS E 397
GLU E 394
 None
 1.38A 4zbqA-5cdfE:
undetectable		 4zbqA-5cdfE:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A210_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 5cdf ATP SYNTHASE SUBUNIT
BETA
(Paracoccus
denitrificans) 		5 / 12 ARG E 291
LEU E 233
VAL E 251
PHE E 249
GLY E 286
 None
 1.48A 5i8fA-5cdfE:
undetectable		 5i8fA-5cdfE:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		 5cdf ATP SYNTHASE SUBUNIT
BETA
(Paracoccus
denitrificans) 		5 / 10 GLN E 412
THR E 329
ILE E 132
THR E 301
ASP E 415
 None
 1.12A 6b5yC-5cdfE:
undetectable
6b5yD-5cdfE:
undetectable		 6b5yC-5cdfE:
11.33
6b5yD-5cdfE:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		 5cdf ATP SYNTHASE SUBUNIT
BETA
(Paracoccus
denitrificans) 		5 / 10 GLN E 412
THR E 329
ILE E 132
THR E 301
ASP E 415
 None
 1.17A 6b68C-5cdfE:
undetectable
6b68D-5cdfE:
undetectable		 6b68C-5cdfE:
11.33
6b68D-5cdfE:
11.33