SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cdi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_1
(PROTEIN (PROTEASE))		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		5 / 11 ALA A 449
GLY A 104
ILE A 107
THR A 124
ILE A 446
 None
 0.88A 1c6yA-5cdiA:
undetectable		 1c6yA-5cdiA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		3 / 3 ASP A 342
LYS A 348
ARG A 351
 None
 1.12A 1ra8A-5cdiA:
undetectable		 1ra8A-5cdiA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		4 / 8 GLY A 416
ASP A 500
THR A  92
ILE A  32
 None
 0.87A 2f9wA-5cdiA:
undetectable
2f9wB-5cdiA:
undetectable		 2f9wA-5cdiA:
21.18
2f9wB-5cdiA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		3 / 3 ARG A 172
ASN A 147
THR A 404
 None
 0.87A 2q63A-5cdiA:
undetectable		 2q63A-5cdiA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		5 / 12 LEU A 420
LEU A 421
VAL A 413
MET A 509
LEU A 132
 None
 1.31A 2q7kA-5cdiA:
undetectable		 2q7kA-5cdiA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_1
(PROTEASE)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		5 / 12 VAL A 468
ILE A 454
GLY A 417
GLY A 416
ILE A 498
 None
 0.83A 2r5pA-5cdiA:
undetectable		 2r5pA-5cdiA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_1
(PROTEASE)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		5 / 12 VAL A 468
ILE A 454
GLY A 417
GLY A 416
ILE A 498
 None
 0.83A 2r5pC-5cdiA:
undetectable		 2r5pC-5cdiA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2REZ_A_ACTA155_0
(MULTIFUNCTIONAL
CYCLASE-DEHYDRATASE-
3-O-METHYL
TRANSFERASE TCMN)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		4 / 5 ARG A 372
GLY A 281
PRO A 280
PHE A 196
 None
 1.32A 2rezA-5cdiA:
undetectable		 2rezA-5cdiA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		4 / 7 GLU A 368
GLU A 364
TYR A 289
ARG A 285
 None
 1.25A 2zt7A-5cdiA:
2.7		 2zt7A-5cdiA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		4 / 6 LEU A 395
ARG A 405
MET A 178
THR A 177
 None
 1.04A 2zxwA-5cdiA:
undetectable
2zxwJ-5cdiA:
undetectable		 2zxwA-5cdiA:
21.33
2zxwJ-5cdiA:
7.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		4 / 6 LEU A 395
ARG A 405
MET A 178
THR A 177
 None
 1.02A 3asnA-5cdiA:
1.0
3asnJ-5cdiA:
undetectable		 3asnA-5cdiA:
21.33
3asnJ-5cdiA:
7.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		4 / 6 LEU A 395
ARG A 405
MET A 178
THR A 177
 None
 0.99A 3asoA-5cdiA:
undetectable
3asoJ-5cdiA:
undetectable		 3asoA-5cdiA:
21.33
3asoJ-5cdiA:
7.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		4 / 5 VAL A 302
VAL A 301
THR A 314
ARG A 303
 None
 1.06A 3bjwA-5cdiA:
undetectable		 3bjwA-5cdiA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_3
(PHOSPHOLIPASE A2)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		4 / 5 VAL A 175
VAL A 176
THR A 325
THR A 173
 None
 1.25A 3bjwG-5cdiA:
undetectable		 3bjwG-5cdiA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		4 / 5 VAL A 302
VAL A 301
THR A 314
ARG A 303
 None
 1.05A 3bjwC-5cdiA:
0.5		 3bjwC-5cdiA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		4 / 5 VAL A 175
VAL A 176
THR A 325
THR A 173
 None
 1.27A 3bjwD-5cdiA:
undetectable		 3bjwD-5cdiA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		5 / 12 ARG A 506
GLN A 126
ILE A 446
VAL A 505
VAL A 413
 None
 0.97A 3gwxB-5cdiA:
undetectable		 3gwxB-5cdiA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_2
(PROTEASE)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		5 / 10 ALA A 449
GLY A 104
ILE A 107
THR A 124
ILE A 446
 None
 0.93A 4njuB-5cdiA:
undetectable		 4njuB-5cdiA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_2
(PROTEASE)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		5 / 10 ALA A 449
GLY A 104
ILE A 107
THR A 124
ILE A 446
 None
 0.92A 4njuD-5cdiA:
undetectable		 4njuD-5cdiA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		5 / 12 GLY A 376
GLY A 193
ARG A 369
ILE A 370
ASP A 342
 None
 1.02A 5l0zA-5cdiA:
undetectable		 5l0zA-5cdiA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		4 / 7 PHE A 100
PRO A 453
ILE A 454
SER A 508
 None
 0.86A 5vkqA-5cdiA:
undetectable
5vkqD-5cdiA:
undetectable		 5vkqA-5cdiA:
16.16
5vkqD-5cdiA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		4 / 7 SER A 508
PHE A 100
PRO A 453
ILE A 454
 None
 0.88A 5vkqA-5cdiA:
undetectable
5vkqB-5cdiA:
undetectable		 5vkqA-5cdiA:
16.16
5vkqB-5cdiA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		4 / 8 SER A 508
PHE A 100
PRO A 453
ILE A 454
 None
 0.86A 5vkqB-5cdiA:
undetectable
5vkqC-5cdiA:
undetectable		 5vkqB-5cdiA:
16.16
5vkqC-5cdiA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		4 / 7 SER A 508
PHE A 100
PRO A 453
ILE A 454
 None
 0.86A 5vkqC-5cdiA:
undetectable
5vkqD-5cdiA:
undetectable		 5vkqC-5cdiA:
16.16
5vkqD-5cdiA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_0
(REGULATORY PROTEIN
TETR)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		5 / 12 MET A 509
ALA A 449
LEU A 420
VAL A 427
ASP A 477
 None
 1.47A 5vlmD-5cdiA:
undetectable		 5vlmD-5cdiA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		3 / 3 MET A 194
ASP A 292
ARG A 351
 None
 1.03A 5z6jA-5cdiA:
undetectable		 5z6jA-5cdiA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		3 / 3 MET A 194
ASP A 292
ARG A 351
 None
 1.11A 5z6kA-5cdiA:
undetectable		 5z6kA-5cdiA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_2
(TUBULIN BETA CHAIN)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		4 / 5 LEU A 373
THR A 297
PRO A 280
ARG A 286
 None
 1.18A 6ew0B-5cdiA:
undetectable		 6ew0B-5cdiA:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_2
(TUBULIN BETA CHAIN)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		4 / 5 LEU A 373
THR A 297
PRO A 280
ARG A 286
 None
 1.18A 6ew0D-5cdiA:
undetectable		 6ew0D-5cdiA:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_2
(TUBULIN BETA CHAIN)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		4 / 5 LEU A 373
THR A 297
PRO A 280
ARG A 286
 None
 1.18A 6ew0H-5cdiA:
undetectable		 6ew0H-5cdiA:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_2
(TUBULIN BETA CHAIN)		 5cdi CHAPERONIN 60B1
(Chlamydomonas
reinhardtii) 		4 / 5 LEU A 373
THR A 297
PRO A 280
ARG A 286
 None
 1.18A 6ew0I-5cdiA:
undetectable		 6ew0I-5cdiA:
9.42