SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cdj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5cdj RUBISCO LARGE
SUBUNIT-BINDING
PROTEIN SUBUNIT
ALPHA, CHLOROPLASTIC
(Chlamydomonas
reinhardtii) 		4 / 6 GLY A 192
THR A 324
THR A 331
ILE A 333
 None
 0.91A 1gtnD-5cdjA:
undetectable
1gtnE-5cdjA:
undetectable		 1gtnD-5cdjA:
16.20
1gtnE-5cdjA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5cdj RUBISCO LARGE
SUBUNIT-BINDING
PROTEIN SUBUNIT
ALPHA, CHLOROPLASTIC
(Chlamydomonas
reinhardtii) 		4 / 7 GLY A 192
THR A 324
THR A 331
ILE A 333
 None
 0.84A 1gtnJ-5cdjA:
undetectable
1gtnK-5cdjA:
undetectable		 1gtnJ-5cdjA:
16.20
1gtnK-5cdjA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RV7_B_AB1B1001_1
(PROTEASE)		 5cdj RUBISCO LARGE
SUBUNIT-BINDING
PROTEIN SUBUNIT
ALPHA, CHLOROPLASTIC
(Chlamydomonas
reinhardtii) 		5 / 11 ALA A 251
VAL A 254
LEU A 289
THR A 296
ALA A 293
 None
 1.16A 1rv7A-5cdjA:
undetectable
1rv7B-5cdjA:
undetectable		 1rv7A-5cdjA:
21.14
1rv7B-5cdjA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 5cdj RUBISCO LARGE
SUBUNIT-BINDING
PROTEIN SUBUNIT
ALPHA, CHLOROPLASTIC
(Chlamydomonas
reinhardtii) 		5 / 12 THR A 223
ILE A 301
LEU A 247
VAL A 273
ILE A 233
 None
 1.17A 3sp9A-5cdjA:
undetectable		 3sp9A-5cdjA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5cdj RUBISCO LARGE
SUBUNIT-BINDING
PROTEIN SUBUNIT
ALPHA, CHLOROPLASTIC
(Chlamydomonas
reinhardtii) 		5 / 12 VAL A 240
ILE A 233
VAL A 254
ILE A 200
LEU A 271
 None
 1.32A 4a84A-5cdjA:
undetectable		 4a84A-5cdjA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_2
(TUBULIN BETA CHAIN)		 5cdj RUBISCO LARGE
SUBUNIT-BINDING
PROTEIN SUBUNIT
ALPHA, CHLOROPLASTIC
(Chlamydomonas
reinhardtii) 		5 / 12 ALA A 258
ALA A 251
ILE A 249
LYS A 277
ALA A 275
 None
 1.00A 5xiwD-5cdjA:
undetectable		 5xiwD-5cdjA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_E_PCFE202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5cdj RUBISCO LARGE
SUBUNIT-BINDING
PROTEIN SUBUNIT
ALPHA, CHLOROPLASTIC
(Chlamydomonas
reinhardtii) 		4 / 8 GLN A 290
ILE A 369
ALA A 347
ARG A 345
 None
 0.88A 6hu9a-5cdjA:
undetectable
6hu9e-5cdjA:
undetectable		 6hu9a-5cdjA:
17.56
6hu9e-5cdjA:
22.46