SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cdo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 5cdo DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B
(Staphylococcus
aureus) 		4 / 5 ARG B 601
ALA B 540
LYS B 502
GLU B 430
 None
 1.09A 1e7cA-5cdoB:
undetectable		 1e7cA-5cdoB:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 5cdo DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B
(Staphylococcus
aureus) 		4 / 5 ILE B 612
LEU B 608
ALA B 614
GLU B 613
 None
 1.20A 1xvaA-5cdoB:
undetectable
1xvaB-5cdoB:
undetectable		 1xvaA-5cdoB:
21.93
1xvaB-5cdoB:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 5cdo DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B
(Staphylococcus
aureus) 		4 / 6 ALA B 614
GLU B 613
ILE B 612
LEU B 608
 None
 0.90A 1xvaA-5cdoB:
undetectable
1xvaB-5cdoB:
undetectable		 1xvaA-5cdoB:
21.93
1xvaB-5cdoB:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 5cdo DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B
(Staphylococcus
aureus) 		5 / 12 ILE B 489
ALA B 484
GLY B 486
GLY B 488
ARG B 447
 None
 1.16A 2okcB-5cdoB:
undetectable		 2okcB-5cdoB:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_A_9PLA501_1
(CYTOCHROME P450 2E1)		 5cdo DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B
(Staphylococcus
aureus) 		4 / 6 LEU B 604
ALA B 514
THR B 507
LEU B 521
 None
 0.95A 3t3zA-5cdoB:
undetectable		 3t3zA-5cdoB:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_B_9PLB501_1
(CYTOCHROME P450 2E1)		 5cdo DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B
(Staphylococcus
aureus) 		4 / 6 LEU B 604
ALA B 514
THR B 507
LEU B 521
 None
 0.94A 3t3zB-5cdoB:
undetectable		 3t3zB-5cdoB:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_D_9PLD501_1
(CYTOCHROME P450 2E1)		 5cdo DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B
(Staphylococcus
aureus) 		4 / 6 LEU B 604
ALA B 514
THR B 507
LEU B 521
 None
 0.99A 3t3zD-5cdoB:
undetectable		 3t3zD-5cdoB:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5cdo DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B
(Staphylococcus
aureus) 		4 / 8 MET B 528
ILE B 482
ARG B 479
VAL B 464
 None
 1.31A 4f4dB-5cdoB:
5.9		 4f4dB-5cdoB:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 5cdo DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B
(Staphylococcus
aureus) 		4 / 7 ARG B 458
GLY B 459
ILE B 461
GLU B 477
 None
 1.08A 4g0vA-5cdoB:
5.5		 4g0vA-5cdoB:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 5cdo DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B
(Staphylococcus
aureus) 		4 / 7 GLY B 459
ILE B 461
ASN B 475
GLU B 477
 None
 0.80A 4g0vA-5cdoB:
5.5		 4g0vA-5cdoB:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1102_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 5cdo DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B
(Staphylococcus
aureus) 		4 / 7 TYR B 538
ILE B 503
TYR B 536
HIS B 501
 None
 1.19A 4g5jA-5cdoB:
undetectable		 4g5jA-5cdoB:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 5cdo DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B
(Staphylococcus
aureus) 		4 / 7 GLY B 436
ASP B 437
GLY B 459
GLU B 477
 None
 0.64A 4koeA-5cdoB:
undetectable
4koeB-5cdoB:
undetectable
4koeD-5cdoB:
29.5		 4koeA-5cdoB:
17.99
4koeB-5cdoB:
17.99
4koeD-5cdoB:
53.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5cdo DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B
(Staphylococcus
aureus) 		4 / 6 MET B 528
ILE B 482
ARG B 479
VAL B 464
 None
 1.25A 4mk4B-5cdoB:
4.8		 4mk4B-5cdoB:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 5cdo DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B
(Staphylococcus
aureus) 		4 / 7 GLY B 436
ASP B 437
GLY B 459
GLU B 477
 None
 0.50A 4z53A-5cdoB:
28.0
4z53B-5cdoB:
27.7		 4z53A-5cdoB:
28.94
4z53B-5cdoB:
28.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5cdo DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B
(Staphylococcus
aureus) 		4 / 6 GLY B 436
ASP B 437
ARG B 458
GLY B 459
 None
 0.65A 5cdnR-5cdoB:
undetectable
5cdnS-5cdoB:
33.8		 5cdnR-5cdoB:
18.03
5cdnS-5cdoB:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5cdo DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B
(Staphylococcus
aureus) 		4 / 6 GLY B 436
ASP B 437
ARG B 458
GLY B 459
 None
 0.73A 5cdnC-5cdoB:
undetectable
5cdnD-5cdoB:
32.6		 5cdnC-5cdoB:
18.03
5cdnD-5cdoB:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5cdo DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B
(Staphylococcus
aureus) 		4 / 6 GLY B 436
ASP B 437
ARG B 458
GLY B 459
 None
 0.75A 5cdnT-5cdoB:
undetectable
5cdnU-5cdoB:
33.2		 5cdnT-5cdoB:
18.03
5cdnU-5cdoB:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 5cdo DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B
(Staphylococcus
aureus) 		4 / 6 GLY B 436
ASP B 437
ARG B 458
GLY B 459
 None
 0.68A 5cdpA-5cdoB:
undetectable
5cdpB-5cdoB:
33.1		 5cdpA-5cdoB:
17.99
5cdpB-5cdoB:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5cdo DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B
(Staphylococcus
aureus) 		4 / 6 ASP B 437
ARG B 458
GLY B 459
GLU B 477
 None
 1.04A 5cdqA-5cdoB:
undetectable
5cdqC-5cdoB:
undetectable
5cdqD-5cdoB:
32.4		 5cdqA-5cdoB:
18.03
5cdqC-5cdoB:
18.03
5cdqD-5cdoB:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IM2_A_BEZA401_0
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL)		 5cdo DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B
(Staphylococcus
aureus) 		5 / 12 PHE B 524
ILE B 503
LEU B 520
LEU B 457
PHE B 485
 None
 1.26A 5im2A-5cdoB:
undetectable		 5im2A-5cdoB:
20.69