SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ce7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MAA_B_DMEB996_1 (ACETYLCHOLINESTERASE)	5ce7	CTD KINASE SUBUNIT GAMMA (Schizosaccharomy ces pombe)	4 / 6	GLU A 47 ILE A 84 TYR A 80 GLY A 79	None	1.09A	1maaB-5ce7A: undetectable 1maaD-5ce7A: undetectable	1maaB-5ce7A: 14.34 1maaD-5ce7A: 14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA3_B_STRB2001_2 (MINERALOCORTICOID RECEPTOR)	5ce7	CTD KINASE SUBUNIT GAMMA (Schizosaccharomy ces pombe)	3 / 3	LEU A 35 LEU A 41 MET A 83	None	0.71A	1ya3B-5ce7A: undetectable	1ya3B-5ce7A: 21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B9L_A_AZZA1009_1 (SERUM ALBUMIN)	5ce7	CTD KINASE SUBUNIT GAMMA (Schizosaccharomy ces pombe)	4 / 8	TYR A 62 SER A 23 GLN A 24 VAL A 95	EPE A 202 (-3.9A) None None None	1.24A	3b9lA-5ce7A: 2.3	3b9lA-5ce7A: 14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KYA_A_FOLA703_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5ce7	CTD KINASE SUBUNIT GAMMA (Schizosaccharomy ces pombe)	5 / 11	VAL A 95 ALA A 101 THR A 133 LEU A 113 VAL A 92	None	1.42A	4kyaA-5ce7A: undetectable	4kyaA-5ce7A: 13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KYA_E_FOLE703_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5ce7	CTD KINASE SUBUNIT GAMMA (Schizosaccharomy ces pombe)	5 / 11	VAL A 95 ALA A 101 THR A 133 LEU A 113 VAL A 92	None	1.43A	4kyaE-5ce7A: undetectable	4kyaE-5ce7A: 13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KYA_G_FOLG703_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5ce7	CTD KINASE SUBUNIT GAMMA (Schizosaccharomy ces pombe)	5 / 11	VAL A 95 ALA A 101 THR A 133 LEU A 113 VAL A 92	None	1.41A	4kyaG-5ce7A: undetectable	4kyaG-5ce7A: 13.40

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MAA_B_DMEB996_1","ACETYLCHOLINESTERASE;ACETYLCHOLINESTERASE","5ce7","CTD KINASE SUBUNIT GAMMA","Schizosaccharomyces pombe",4,"GLU A  47;ILE A  84;TYR A  80;GLY A  79","None","1.09A","1maaB-5ce7A:undetectable;1maaD-5ce7A:undetectable","1maaB-5ce7A:14.34;1maaD-5ce7A:14.34"],["1YA3_B_STRB2001_2","MINERALOCORTICOID RECEPTOR","5ce7","CTD KINASE SUBUNIT GAMMA","Schizosaccharomyces pombe",3,"LEU A  35;LEU A  41;MET A  83","None","0.71A","1ya3B-5ce7A:undetectable","1ya3B-5ce7A:21.18"],["3B9L_A_AZZA1009_1","SERUM ALBUMIN","5ce7","CTD KINASE SUBUNIT GAMMA","Schizosaccharomyces pombe",4,"TYR A  62;SER A  23;GLN A  24;VAL A  95","EPE A 202 (-3.9A);None;None;None","1.24A","3b9lA-5ce7A:2.3","3b9lA-5ce7A:14.07"],["4KYA_A_FOLA703_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","5ce7","CTD KINASE SUBUNIT GAMMA","Schizosaccharomyces pombe",5,"VAL A  95;ALA A 101;THR A 133;LEU A 113;VAL A  92","None","1.42A","4kyaA-5ce7A:undetectable","4kyaA-5ce7A:13.40"],["4KYA_E_FOLE703_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","5ce7","CTD KINASE SUBUNIT GAMMA","Schizosaccharomyces pombe",5,"VAL A  95;ALA A 101;THR A 133;LEU A 113;VAL A  92","None","1.43A","4kyaE-5ce7A:undetectable","4kyaE-5ce7A:13.40"],["4KYA_G_FOLG703_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","5ce7","CTD KINASE SUBUNIT GAMMA","Schizosaccharomyces pombe",5,"VAL A  95;ALA A 101;THR A 133;LEU A 113;VAL A  92","None","1.41A","4kyaG-5ce7A:undetectable","4kyaG-5ce7A:13.40"]]