SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ce9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4001_1
(SERUM ALBUMIN)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 5 ARG A 278
ALA A  50
ASP A 145
GLY A 149
 None
 1.16A 1e7bA-5ce9A:
undetectable		 1e7bA-5ce9A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_A_SAMA300_0
(HEMK PROTEIN)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 12 PHE A 260
ILE A 242
GLY A 258
THR A 246
ASN A 240
 NA  A 406 (-4.6A)
None
None
None
None
 1.06A 1nv8A-5ce9A:
undetectable		 1nv8A-5ce9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 12 PHE A 260
ILE A 242
GLY A 258
THR A 246
ASN A 240
 NA  A 406 (-4.6A)
None
None
None
None
 1.06A 1sg9A-5ce9A:
undetectable		 1sg9A-5ce9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_A_CHDA1_0
(LIVER
CARBOXYLESTERASE 1)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 5 TRP A 337
GLY A 149
LEU A 180
PRO A 336
 None
 1.21A 2dqyA-5ce9A:
undetectable		 2dqyA-5ce9A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A 272
ALA A 263
SER A 262
GLY A 247
ILE A 254
 None
 1.17A 2uxpB-5ce9A:
undetectable		 2uxpB-5ce9A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 5 HIS A 239
HIS A 243
VAL A 276
HIS A 273
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
 0.92A 2wkoF-5ce9A:
undetectable		 2wkoF-5ce9A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A  87
HIS A 108
HIS A 239
ASN A 240
HIS A 243
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
 0.30A 2zweA-5ce9A:
21.0
2zweB-5ce9A:
undetectable		 2zweA-5ce9A:
22.44
2zweB-5ce9A:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A 239
HIS A 243
HIS A  87
HIS A 108
PRO A  17
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
None
 1.09A 2zweA-5ce9A:
21.0
2zweB-5ce9A:
undetectable		 2zweA-5ce9A:
22.44
2zweB-5ce9A:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A  87
HIS A 108
HIS A 239
ASN A 240
HIS A 243
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
 0.28A 2zwfA-5ce9A:
21.0
2zwfB-5ce9A:
undetectable		 2zwfA-5ce9A:
22.44
2zwfB-5ce9A:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A 239
HIS A 243
HIS A  87
HIS A 108
PRO A  17
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
None
 1.13A 2zwfA-5ce9A:
21.0
2zwfB-5ce9A:
undetectable		 2zwfA-5ce9A:
22.44
2zwfB-5ce9A:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A  87
HIS A 108
HIS A 239
ASN A 240
HIS A 243
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
 0.25A 2zwgA-5ce9A:
21.0
2zwgB-5ce9A:
undetectable		 2zwgA-5ce9A:
22.44
2zwgB-5ce9A:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		3 / 3 ARG A 314
ASP A 319
ASP A  35
 None
 0.89A 3jayA-5ce9A:
undetectable		 3jayA-5ce9A:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		3 / 3 ARG A 314
ASP A 319
ASP A  35
 None
 0.78A 3jb2A-5ce9A:
undetectable		 3jb2A-5ce9A:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		3 / 3 ARG A 314
ASP A 319
ASP A  35
 None
 0.69A 3jb3A-5ce9A:
undetectable		 3jb3A-5ce9A:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 7 VAL A  54
LEU A 155
TYR A 156
LEU A 128
 None
 0.89A 3qeoB-5ce9A:
undetectable		 3qeoB-5ce9A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		3 / 3 HIS A 108
HIS A 117
HIS A  87
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
 0.20A 3qpkA-5ce9A:
undetectable		 3qpkA-5ce9A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		3 / 3 HIS A 108
HIS A 117
HIS A  87
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
 0.18A 3qpkB-5ce9A:
undetectable		 3qpkB-5ce9A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 7 LEU A 112
TYR A  90
LEU A 105
TYR A 221
 None
 1.09A 4b3qA-5ce9A:
undetectable		 4b3qA-5ce9A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		6 / 7 HIS A  87
HIS A 108
HIS A 239
ASN A 240
HIS A 243
ALA A 263
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
 0.44A 4p6sA-5ce9A:
21.2		 4p6sA-5ce9A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 7 HIS A 243
HIS A 239
HIS A 108
HIS A  87
ALA A 263
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
None
 1.17A 4p6sA-5ce9A:
21.2		 4p6sA-5ce9A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 7 HIS A 243
HIS A 273
HIS A 108
HIS A  87
ALA A 263
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
None
 1.39A 4p6sA-5ce9A:
21.2		 4p6sA-5ce9A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 7 HIS A  87
HIS A 108
HIS A 239
ASN A 240
HIS A 243
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
 0.45A 4p6sB-5ce9A:
21.1		 4p6sB-5ce9A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 7 HIS A 108
HIS A  87
HIS A 243
HIS A 239
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
 0.96A 4p6sB-5ce9A:
21.1		 4p6sB-5ce9A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 5 GLN A  97
LEU A 105
SER A 104
ASP A 228
 None
 1.23A 4qtuD-5ce9A:
undetectable		 4qtuD-5ce9A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ5_B_ACTB404_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		3 / 3 TYR A 122
ARG A  46
LYS A 126
 None
 1.40A 4wq5B-5ce9A:
undetectable		 4wq5B-5ce9A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 10 ILE A  66
TYR A  62
LEU A 128
PHE A 124
ILE A 242
 None
 1.17A 5hw8C-5ce9A:
undetectable
5hw8H-5ce9A:
undetectable		 5hw8C-5ce9A:
16.62
5hw8H-5ce9A:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		6 / 7 HIS A  87
HIS A 108
HIS A 239
ASN A 240
HIS A 243
ALA A 263
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
 0.38A 5i3aA-5ce9A:
21.3		 5i3aA-5ce9A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 7 HIS A 243
HIS A 239
HIS A 108
HIS A  87
ALA A 263
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
None
 1.16A 5i3aA-5ce9A:
21.3		 5i3aA-5ce9A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 7 HIS A 243
HIS A 273
HIS A 108
HIS A  87
ALA A 263
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
None
 1.44A 5i3aA-5ce9A:
21.3		 5i3aA-5ce9A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		6 / 7 HIS A  87
HIS A 108
HIS A 239
ASN A 240
HIS A 243
ALA A 263
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
 0.36A 5i3aB-5ce9A:
21.2		 5i3aB-5ce9A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 7 HIS A 243
HIS A 239
HIS A 108
HIS A  87
ALA A 263
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
None
 1.17A 5i3aB-5ce9A:
21.2		 5i3aB-5ce9A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 7 HIS A 243
HIS A 273
HIS A 108
HIS A  87
ALA A 263
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
None
 1.42A 5i3aB-5ce9A:
21.2		 5i3aB-5ce9A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		6 / 7 HIS A  87
HIS A 108
HIS A 239
ASN A 240
HIS A 243
ALA A 263
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
 0.42A 5i3bA-5ce9A:
21.4		 5i3bA-5ce9A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 7 HIS A 243
HIS A 239
HIS A 108
HIS A  87
ALA A 263
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
None
 1.15A 5i3bA-5ce9A:
21.4		 5i3bA-5ce9A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 7 HIS A 243
HIS A 273
HIS A 108
HIS A  87
ALA A 263
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
None
 1.44A 5i3bA-5ce9A:
21.4		 5i3bA-5ce9A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 5 HIS A  87
HIS A 108
HIS A 243
ALA A 263
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
 0.37A 5i3bB-5ce9A:
21.3		 5i3bB-5ce9A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 5 HIS A  87
HIS A 117
HIS A 243
ALA A 263
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
 1.38A 5i3bB-5ce9A:
21.3		 5i3bB-5ce9A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 5 HIS A 243
HIS A 239
HIS A  87
ALA A 263
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
None
 1.06A 5i3bB-5ce9A:
21.3		 5i3bB-5ce9A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 5 HIS A 243
HIS A 273
HIS A  87
ALA A 263
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
None
 0.90A 5i3bB-5ce9A:
21.3		 5i3bB-5ce9A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_A_MMSA514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		6 / 10 HIS A  87
HIS A 108
HIS A 239
ASN A 240
HIS A 243
LEU A 244
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
 0.46A 5m8nA-5ce9A:
20.2		 5m8nA-5ce9A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		6 / 10 HIS A  87
HIS A 108
HIS A 239
ASN A 240
HIS A 243
LEU A 244
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
 0.44A 5m8nB-5ce9A:
20.3		 5m8nB-5ce9A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 9 HIS A  87
HIS A 108
HIS A 239
ASN A 240
HIS A 243
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
 0.42A 5m8nC-5ce9A:
20.4		 5m8nC-5ce9A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_D_MMSD515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 9 HIS A 108
HIS A 239
ASN A 240
HIS A 243
LEU A 244
 CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
 0.35A 5m8nD-5ce9A:
0.0		 5m8nD-5ce9A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 7 HIS A 108
HIS A 239
ASN A 240
HIS A 243
LEU A 244
 CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
 0.28A 5m8rA-5ce9A:
20.3		 5m8rA-5ce9A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 8 HIS A 108
HIS A 239
ASN A 240
HIS A 243
LEU A 244
 CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
 0.25A 5m8rB-5ce9A:
20.1		 5m8rB-5ce9A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		6 / 8 HIS A 108
HIS A 239
ASN A 240
HIS A 243
LEU A 244
GLY A 258
 CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
None
 0.31A 5m8rC-5ce9A:
16.5		 5m8rC-5ce9A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 8 HIS A 108
HIS A 239
ASN A 240
HIS A 243
LEU A 244
 CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
 0.26A 5m8rD-5ce9A:
20.8		 5m8rD-5ce9A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 4 HIS A 108
HIS A 273
HIS A 117
HIS A  87
 CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
 0.88A 5mhwA-5ce9A:
undetectable		 5mhwA-5ce9A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 4 HIS A 108
HIS A 273
HIS A 117
HIS A  87
 CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
 0.87A 5mhxA-5ce9A:
undetectable		 5mhxA-5ce9A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 4 HIS A 108
HIS A 273
HIS A 117
HIS A  87
 CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
 0.87A 5mhyA-5ce9A:
undetectable		 5mhyA-5ce9A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 4 HIS A 108
HIS A 273
HIS A 117
HIS A  87
 CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
 0.87A 5mhzA-5ce9A:
undetectable		 5mhzA-5ce9A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 4 HIS A 108
HIS A 273
HIS A 117
HIS A  87
 CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
 0.87A 5mi1A-5ce9A:
undetectable		 5mi1A-5ce9A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 4 HIS A 108
HIS A 273
HIS A 117
HIS A  87
 CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
 0.87A 5mi2A-5ce9A:
undetectable		 5mi2A-5ce9A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 4 HIS A 108
HIS A 273
HIS A 117
HIS A  87
 CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
 0.87A 5miaA-5ce9A:
undetectable		 5miaA-5ce9A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 4 HIS A 108
HIS A 273
HIS A 117
HIS A  87
 CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
 0.87A 5mibA-5ce9A:
undetectable		 5mibA-5ce9A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 4 HIS A 108
HIS A 273
HIS A 117
HIS A  87
 CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
 0.86A 5micA-5ce9A:
undetectable		 5micA-5ce9A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 4 HIS A 108
HIS A 273
HIS A 117
HIS A  87
 CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
 0.87A 5midA-5ce9A:
undetectable		 5midA-5ce9A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 4 HIS A 108
HIS A 273
HIS A 117
HIS A  87
 CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
 0.87A 5mieA-5ce9A:
undetectable		 5mieA-5ce9A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		3 / 3 HIS A 108
HIS A 117
HIS A  87
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
 0.19A 5migA-5ce9A:
undetectable		 5migA-5ce9A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OCS_A_ACTA402_0
(PUTATIVE
NADH-DEPENTDENT
FLAVIN
OXIDOREDUCTASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 5 CYH A  91
ILE A 107
HIS A 273
HIS A 239
 CU  A 402 (-3.5A)
None
CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
 1.29A 5ocsA-5ce9A:
undetectable		 5ocsA-5ce9A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OCS_C_ACTC402_0
(PUTATIVE
NADH-DEPENTDENT
FLAVIN
OXIDOREDUCTASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 5 CYH A  91
ILE A 107
HIS A 273
HIS A 239
 CU  A 402 (-3.5A)
None
CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
 1.29A 5ocsC-5ce9A:
undetectable		 5ocsC-5ce9A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A  87
HIS A 108
HIS A 239
ASN A 240
HIS A 243
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
 0.37A 5z0fA-5ce9A:
21.0
5z0fB-5ce9A:
undetectable		 5z0fA-5ce9A:
14.90
5z0fB-5ce9A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A 239
HIS A 243
HIS A  87
HIS A 108
PRO A  17
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
None
 1.10A 5z0fA-5ce9A:
21.0
5z0fB-5ce9A:
undetectable		 5z0fA-5ce9A:
14.90
5z0fB-5ce9A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A 243
HIS A 239
HIS A 108
HIS A  87
VAL A  86
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
None
 1.11A 5z0fA-5ce9A:
21.0
5z0fB-5ce9A:
undetectable		 5z0fA-5ce9A:
14.90
5z0fB-5ce9A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A  87
HIS A 108
HIS A 239
ASN A 240
HIS A 243
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
 0.33A 5z0gA-5ce9A:
20.9
5z0gB-5ce9A:
undetectable		 5z0gA-5ce9A:
14.90
5z0gB-5ce9A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A 239
HIS A 243
HIS A  87
HIS A 108
PRO A  17
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
None
 1.10A 5z0gA-5ce9A:
20.9
5z0gB-5ce9A:
undetectable		 5z0gA-5ce9A:
14.90
5z0gB-5ce9A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A 243
HIS A 239
HIS A 108
HIS A  87
VAL A  86
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
None
 1.13A 5z0gA-5ce9A:
20.9
5z0gB-5ce9A:
undetectable		 5z0gA-5ce9A:
14.90
5z0gB-5ce9A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A  87
HIS A 108
HIS A 239
ASN A 240
HIS A 243
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
 0.29A 5z0hA-5ce9A:
21.0
5z0hB-5ce9A:
undetectable		 5z0hA-5ce9A:
14.90
5z0hB-5ce9A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A  87
HIS A 108
HIS A 239
ASN A 240
HIS A 243
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
 0.32A 5z0iA-5ce9A:
21.0
5z0iB-5ce9A:
undetectable		 5z0iA-5ce9A:
14.90
5z0iB-5ce9A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A 108
HIS A  87
HIS A 243
HIS A 239
ASP A 277
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
None
 1.48A 5z0iA-5ce9A:
21.0
5z0iB-5ce9A:
undetectable		 5z0iA-5ce9A:
14.90
5z0iB-5ce9A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A 239
HIS A 243
HIS A  87
HIS A 108
PRO A  17
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
None
 1.12A 5z0iA-5ce9A:
21.0
5z0iB-5ce9A:
undetectable		 5z0iA-5ce9A:
14.90
5z0iB-5ce9A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A 243
HIS A 239
HIS A 108
HIS A  87
VAL A  86
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
None
 1.12A 5z0iA-5ce9A:
21.0
5z0iB-5ce9A:
undetectable		 5z0iA-5ce9A:
14.90
5z0iB-5ce9A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A  87
HIS A 108
HIS A 239
ASN A 240
HIS A 243
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
 0.32A 5z0jA-5ce9A:
20.9
5z0jB-5ce9A:
undetectable		 5z0jA-5ce9A:
14.90
5z0jB-5ce9A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A 239
HIS A 243
HIS A  87
HIS A 108
PRO A  17
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
None
 1.09A 5z0jA-5ce9A:
20.9
5z0jB-5ce9A:
undetectable		 5z0jA-5ce9A:
14.90
5z0jB-5ce9A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A 243
HIS A 239
HIS A 108
HIS A  87
VAL A  86
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
None
 1.11A 5z0jA-5ce9A:
20.9
5z0jB-5ce9A:
undetectable		 5z0jA-5ce9A:
14.90
5z0jB-5ce9A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A  87
HIS A 108
HIS A 239
ASN A 240
HIS A 243
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
 0.29A 5z0kA-5ce9A:
20.9
5z0kB-5ce9A:
undetectable		 5z0kA-5ce9A:
14.90
5z0kB-5ce9A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A 108
HIS A  87
HIS A 243
HIS A 239
ASP A 277
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
None
 1.50A 5z0kA-5ce9A:
20.9
5z0kB-5ce9A:
undetectable		 5z0kA-5ce9A:
14.90
5z0kB-5ce9A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A 239
HIS A 243
HIS A  87
HIS A 108
PRO A  17
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
None
 1.12A 5z0kA-5ce9A:
20.9
5z0kB-5ce9A:
undetectable		 5z0kA-5ce9A:
14.90
5z0kB-5ce9A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A  87
HIS A 108
HIS A 239
ASN A 240
HIS A 243
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
 0.27A 5z0lA-5ce9A:
21.0
5z0lB-5ce9A:
undetectable		 5z0lA-5ce9A:
14.90
5z0lB-5ce9A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 11 HIS A  87
HIS A 108
HIS A 239
ASN A 240
HIS A 243
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
 0.35A 5z0mA-5ce9A:
21.0
5z0mB-5ce9A:
undetectable		 5z0mA-5ce9A:
14.90
5z0mB-5ce9A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA607_0
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		3 / 3 HIS A 239
HIS A 243
HIS A 273
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
 0.13A 5zrdA-5ce9A:
3.1		 5zrdA-5ce9A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 5 HIS A 117
HIS A  87
PHE A 260
HIS A 108
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
NA  A 406 (-4.6A)
CU  A 402 ( 3.2A)
 1.09A 5zrdB-5ce9A:
3.6		 5zrdB-5ce9A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		5 / 5 HIS A 239
HIS A 243
PHE A 269
HIS A 272
HIS A 273
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 401 ( 4.9A)
None
CU  A 401 ( 3.2A)
 0.26A 5zrdB-5ce9A:
3.6		 5zrdB-5ce9A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 5 HIS A  87
CYH A  91
HIS A 108
PHE A 269
 CU  A 402 ( 3.2A)
CU  A 402 (-3.5A)
CU  A 402 ( 3.2A)
CU  A 401 ( 4.9A)
 1.06A 5zrdB-5ce9A:
3.6		 5zrdB-5ce9A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 5 HIS A  87
HIS A 108
HIS A 117
PHE A 269
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 4.9A)
 0.28A 5zrdB-5ce9A:
3.6		 5zrdB-5ce9A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 5 HIS A 239
HIS A 243
HIS A 273
PHE A 113
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
None
 0.96A 5zrdB-5ce9A:
3.6		 5zrdB-5ce9A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 4 HIS A 239
HIS A 243
HIS A 272
HIS A 273
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
 0.25A 5zrdC-5ce9A:
3.1		 5zrdC-5ce9A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 5 HIS A  87
CYH A  91
HIS A 108
PHE A 269
 CU  A 402 ( 3.2A)
CU  A 402 (-3.5A)
CU  A 402 ( 3.2A)
CU  A 401 ( 4.9A)
 1.08A 5zrdC-5ce9A:
3.1		 5zrdC-5ce9A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 5 HIS A  87
HIS A 108
HIS A 117
PHE A 269
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 4.9A)
 0.24A 5zrdC-5ce9A:
3.1		 5zrdC-5ce9A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 5 HIS A 239
HIS A 243
HIS A 273
PHE A 113
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
None
 1.01A 5zrdC-5ce9A:
3.1		 5zrdC-5ce9A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 5 HIS A  87
CYH A  91
HIS A 108
PHE A 269
 CU  A 402 ( 3.2A)
CU  A 402 (-3.5A)
CU  A 402 ( 3.2A)
CU  A 401 ( 4.9A)
 1.06A 5zrdD-5ce9A:
4.4		 5zrdD-5ce9A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 5 HIS A  87
HIS A 108
HIS A 117
PHE A 269
 CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 402 ( 3.2A)
CU  A 401 ( 4.9A)
 0.32A 5zrdD-5ce9A:
4.4		 5zrdD-5ce9A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 5 HIS A 239
HIS A 243
HIS A 273
PHE A 113
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
None
 0.98A 5zrdD-5ce9A:
4.4		 5zrdD-5ce9A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 5ce9 POLYPHENOL OXIDASE
(Juglans
regia) 		4 / 4 HIS A 239
HIS A 243
HIS A 272
HIS A 273
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
 0.26A 5zrdD-5ce9A:
4.4		 5zrdD-5ce9A:
22.53