SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cec'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_1
(PROTEASE)		 5cec BD3460
(Bdellovibrio
bacteriovorus) 		6 / 12 LEU B  76
ASP B 110
ALA B 108
ASP B 107
ILE B 116
VAL B  79
 SO4  B 301 (-4.4A)
None
None
None
None
None
 1.43A 2ieoA-5cecB:
undetectable		 2ieoA-5cecB:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5cec BD3460
(Bdellovibrio
bacteriovorus) 		5 / 12 ASN B 142
ILE B 149
THR B 145
VAL B 122
ILE B 124
 None
 1.21A 3kpbA-5cecB:
undetectable		 3kpbA-5cecB:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 5cec BD3460
(Bdellovibrio
bacteriovorus) 		4 / 8 ALA B 112
ILE B 116
LEU B 100
ALA B 138
 None
 0.67A 3r9tA-5cecB:
undetectable		 3r9tA-5cecB:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 5cec BD3460
(Bdellovibrio
bacteriovorus) 		5 / 12 LEU B  82
LEU B  83
LEU B  76
GLY B  40
LEU B  42
 None
None
SO4  B 301 (-4.4A)
None
None
 0.98A 4pxmA-5cecB:
undetectable		 4pxmA-5cecB:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 5cec BD3460
(Bdellovibrio
bacteriovorus) 		4 / 8 LEU B 134
ASN B 141
ALA B 138
GLU B 113
 None
 0.91A 4zbqA-5cecB:
undetectable		 4zbqA-5cecB:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DX3_A_ESTA601_1
(ESTROGEN RECEPTOR)		 5cec BD3460
(Bdellovibrio
bacteriovorus) 		5 / 10 LEU B  83
GLU B 114
LEU B  76
GLY B  40
LEU B  42
 None
None
SO4  B 301 (-4.4A)
None
None
 1.32A 5dx3A-5cecB:
undetectable		 5dx3A-5cecB:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 5cec BD3460
(Bdellovibrio
bacteriovorus) 		4 / 7 PHE B 102
ALA B 112
GLY B  74
THR B 145
 None
 0.81A 5ybbB-5cecB:
undetectable		 5ybbB-5cecB:
18.63