SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cej'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)		 5cej 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Yersinia
pestis) 		4 / 7 SER A  65
THR A  68
VAL A  69
ALA A 120
 None
 1.10A 1fo4B-5cejA:
undetectable		 1fo4B-5cejA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5cej 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Yersinia
pestis) 		5 / 12 TYR A 151
ILE A  17
GLY A 137
ALA A 156
GLY A 182
 None
 1.04A 1kiaA-5cejA:
7.8		 1kiaA-5cejA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5cej 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Yersinia
pestis) 		5 / 12 TYR A 151
ILE A  17
GLY A 137
ALA A 156
GLY A 182
 None
 1.05A 1kiaB-5cejA:
5.8		 1kiaB-5cejA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5cej 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Yersinia
pestis) 		5 / 12 TYR A 151
ILE A  17
GLY A 137
ALA A 156
GLY A 182
 None
 1.05A 1kiaC-5cejA:
7.7		 1kiaC-5cejA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5cej 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Yersinia
pestis) 		5 / 12 TYR A 151
ILE A  17
GLY A 137
ALA A 156
GLY A 182
 None
 1.07A 1nbhB-5cejA:
7.5		 1nbhB-5cejA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5cej 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Yersinia
pestis) 		5 / 12 TYR A 151
ILE A  17
GLY A 137
ALA A 156
GLY A 182
 None
 1.14A 1nbiA-5cejA:
7.5		 1nbiA-5cejA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5cej 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Yersinia
pestis) 		5 / 12 TYR A 151
ILE A  17
GLY A 137
ALA A 156
GLY A 182
 None
 1.14A 1nbiB-5cejA:
7.6		 1nbiB-5cejA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 5cej 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Yersinia
pestis) 		5 / 12 LEU A 235
VAL A 179
ILE A 215
LEU A  25
LEU A  24
 None
 1.15A 1s19A-5cejA:
undetectable		 1s19A-5cejA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 5cej 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Yersinia
pestis) 		4 / 6 ALA A 220
PHE A   3
ILE A  82
VAL A  84
 None
 0.98A 2cizA-5cejA:
undetectable		 2cizA-5cejA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5cej 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A  21
ALA A  20
GLY A  16
ILE A 215
GLY A  12
 None
 0.76A 2qe6A-5cejA:
5.9		 2qe6A-5cejA:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5cej 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A  21
ALA A  20
GLY A  16
ILE A 215
GLY A  12
 None
 0.81A 2qe6B-5cejA:
5.9		 2qe6B-5cejA:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBZ_A_VDXA501_1
(CYTOCHROME P450-SU1)		 5cej 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Yersinia
pestis) 		5 / 11 THR A 175
SER A 113
VAL A 179
ILE A 136
ALA A 223
 None
 1.21A 2zbzA-5cejA:
undetectable		 2zbzA-5cejA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_A_SAMA501_0
(SPERMIDINE SYNTHASE)		 5cej 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Yersinia
pestis) 		5 / 12 GLN A 203
TYR A 151
ILE A 184
GLY A 182
GLY A 210
 None
 0.93A 3bwcA-5cejA:
5.5		 3bwcA-5cejA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_B_KANB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5cej 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Yersinia
pestis) 		3 / 3 ALA A 216
ARG A  28
LYS A   2
 None
 1.12A 3kp5B-5cejA:
undetectable		 3kp5B-5cejA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_1
(PROTEASE)		 5cej 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Yersinia
pestis) 		6 / 9 ALA A 154
VAL A 140
GLY A 137
ILE A 136
ILE A  89
ILE A 106
 None
 1.08A 3s43A-5cejA:
undetectable		 3s43A-5cejA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_1
(PROTEASE)		 5cej 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A 154
VAL A 140
GLY A 137
ILE A 136
ILE A  89
 None
 1.02A 3s56A-5cejA:
undetectable		 3s56A-5cejA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 5cej 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Yersinia
pestis) 		4 / 5 SER A 138
ILE A  17
TYR A 151
GLY A 182
 None
 1.04A 3uboB-5cejA:
6.8		 3uboB-5cejA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 5cej 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Yersinia
pestis) 		5 / 11 ILE A  21
ILE A  17
GLY A  16
VAL A 237
GLY A 210
 None
 0.96A 4ac9B-5cejA:
5.3
4ac9C-5cejA:
5.7		 4ac9B-5cejA:
21.27
4ac9C-5cejA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 5cej 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Yersinia
pestis) 		4 / 8 GLY A  88
ALA A  87
GLY A  18
ILE A  17
 None
 0.65A 5kr1B-5cejA:
undetectable		 5kr1B-5cejA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5cej 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Yersinia
pestis) 		5 / 12 VAL A  32
LEU A  49
VAL A  10
GLY A  18
ILE A  21
 None
 1.07A 5vopA-5cejA:
2.6		 5vopA-5cejA:
23.58