SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cer'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_C_IPHC802_0
(PHENOL HYDROXYLASE)		 5cer BD0816
BD3460
(Bdellovibrio
bacteriovorus;
Bdellovibrio
bacteriovorus) 		5 / 10 ASP B 179
GLY B 175
GLN B 140
VAL B 171
GLY A 335
 None
 1.46A 1fohC-5cerB:
undetectable		 1fohC-5cerB:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_D_IPHD802_0
(PHENOL HYDROXYLASE)		 5cer BD0816
BD3460
(Bdellovibrio
bacteriovorus;
Bdellovibrio
bacteriovorus) 		5 / 10 ASP B 179
GLY B 175
GLN B 140
VAL B 171
GLY A 335
 None
 1.43A 1fohD-5cerB:
undetectable		 1fohD-5cerB:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 12 ALA A  57
LYS A  61
SER A 239
ASN A 241
LYS A 345
GLY A 347
 None
 0.25A 1ghmA-5cerA:
18.5		 1ghmA-5cerA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		7 / 12 ALA A  57
LYS A  61
SER A 239
ASN A 241
THR A 330
LYS A 345
GLY A 347
 None
 0.33A 1i2wA-5cerA:
18.6		 1i2wA-5cerA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 12 ALA A  57
LYS A  61
SER A 239
ASN A 241
THR A 330
GLY A 347
 None
 0.35A 1i2wB-5cerA:
18.7		 1i2wB-5cerA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_C_THAC3_1
(LIVER
CARBOXYLESTERASE I)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 12 THR A  80
VAL A  96
LEU A  82
LEU A  94
PHE A 104
 None
 1.03A 1mx1C-5cerA:
undetectable		 1mx1C-5cerA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		4 / 6 ASN A 280
GLY A 147
THR A 149
PRO A 150
 None
 0.87A 1n4fA-5cerA:
undetectable		 1n4fA-5cerA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_C_IPHC6032_0
(PHENOL
2-MONOOXYGENASE)		 5cer BD0816
BD3460
(Bdellovibrio
bacteriovorus;
Bdellovibrio
bacteriovorus) 		5 / 10 ASP B 179
GLY B 175
GLN B 140
VAL B 171
GLY A 335
 None
 1.46A 1pn0C-5cerB:
undetectable		 1pn0C-5cerB:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_D_IPHD6042_0
(PHENOL
2-MONOOXYGENASE)		 5cer BD0816
BD3460
(Bdellovibrio
bacteriovorus;
Bdellovibrio
bacteriovorus) 		5 / 10 ASP B 179
GLY B 175
GLN B 140
VAL B 171
GLY A 335
 None
 1.45A 1pn0D-5cerB:
undetectable		 1pn0D-5cerB:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		4 / 6 ASP A 318
TYR A 314
ASP A  75
GLU A 411
 None
 1.30A 1rjdB-5cerA:
undetectable		 1rjdB-5cerA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		4 / 6 ASP A 318
TYR A 314
ASP A  75
GLU A 411
 None
 1.27A 1rjdC-5cerA:
undetectable		 1rjdC-5cerA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_B_NOVB2300_1
(TOPOISOMERASE IV
SUBUNIT B)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 12 ASN A 236
SER A 321
ASP A 326
ASP A 418
ALA A 226
 None
 1.10A 1s14B-5cerA:
undetectable		 1s14B-5cerA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 12 LYS A  61
SER A 239
ASN A 241
THR A 330
LYS A 345
GLY A 347
 None
 0.35A 1ymxA-5cerA:
18.1		 1ymxA-5cerA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		4 / 8 GLY A 347
PHE A 274
ILE A  59
ASN A 236
 None
 1.03A 2a8tB-5cerA:
undetectable		 2a8tB-5cerA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA501_1
(CYTOCHROME P450 2B4)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		4 / 7 SER A 239
MET A 235
THR A 301
ILE A 272
 None
 0.81A 2bdmA-5cerA:
undetectable		 2bdmA-5cerA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_A_GBNA2414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		4 / 8 GLY A 253
THR A 254
ALA A 255
ALA A 256
 None
 0.55A 2ej3A-5cerA:
undetectable		 2ej3A-5cerA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_B_ADNB2002_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		4 / 6 GLU A 292
ASN A  30
PRO A  55
ALA A 352
 None
 1.22A 2ejfB-5cerA:
undetectable		 2ejfB-5cerA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		4 / 8 GLY A 253
GLY A 252
ALA A 255
ALA A 256
 None
 0.60A 2ha4A-5cerA:
undetectable		 2ha4A-5cerA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		4 / 7 GLY A 253
GLY A 252
ALA A 255
ALA A 256
 None
 0.63A 2ha4B-5cerA:
undetectable		 2ha4B-5cerA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_1
(PROTEASE)		 5cer BD3460
(Bdellovibrio
bacteriovorus) 		6 / 12 LEU B  76
ASP B 110
ALA B 108
ASP B 107
ILE B 116
VAL B  79
 None
 1.46A 2ieoA-5cerB:
undetectable		 2ieoA-5cerB:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		3 / 3 PRO A 102
ASN A 250
ARG A 100
 None
 1.06A 2qeuB-5cerA:
undetectable		 2qeuB-5cerA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		3 / 3 LEU A 415
ASN A 107
ARG A 185
 None
 0.84A 2qhfA-5cerA:
undetectable		 2qhfA-5cerA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 12 ALA A 263
THR A 254
ILE A 272
ASP A 268
PHE A 257
 None
 1.27A 2v95A-5cerA:
undetectable		 2v95A-5cerA:
25.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 11 ALA A  57
PHE A 274
ASN A 291
GLY A 347
ILE A  59
 None
 1.45A 2zmaA-5cerA:
11.9		 2zmaA-5cerA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 12 GLY A 252
LEU A 134
HIS A  78
LEU A  72
TYR A  76
 None
 1.12A 3cs8A-5cerA:
undetectable		 3cs8A-5cerA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 12 ASP A 136
ILE A 145
GLY A 146
GLY A 147
VAL A 148
 None
 0.97A 3cyxB-5cerA:
undetectable		 3cyxB-5cerA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_0
(MODIFICATION
METHYLASE HHAI)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 12 GLY A 347
ASN A 240
ILE A 243
LEU A 247
ASN A 291
 None
 1.17A 3eeoA-5cerA:
undetectable		 3eeoA-5cerA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		4 / 7 GLY A 277
GLY A 279
THR A 149
ALA A 244
 None
 0.72A 3fpjB-5cerA:
undetectable		 3fpjB-5cerA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 12 LYS A  61
SER A 239
ASN A 241
THR A 330
LYS A 345
GLY A 347
 None
 0.32A 3hlwA-5cerA:
18.1		 3hlwA-5cerA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 12 SER A 239
ASN A 241
THR A 330
LYS A 345
THR A 346
GLY A 347
 None
 0.28A 3hlwB-5cerA:
18.2		 3hlwB-5cerA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 12 LYS A  61
ASN A 241
LYS A 345
THR A 346
GLY A 347
 None
 0.20A 3huoA-5cerA:
18.2		 3huoA-5cerA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 12 SER A 239
THR A 330
LYS A 345
THR A 346
GLY A 347
THR A 348
 None
 0.46A 3ny4A-5cerA:
17.3		 3ny4A-5cerA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 12 LYS A  61
SER A 239
ASN A 241
LYS A 345
GLY A 347
 None
 0.29A 3q07A-5cerA:
18.0		 3q07A-5cerA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 12 LYS A  61
SER A 239
ASN A 241
LYS A 345
GLY A 347
 None
 0.37A 3q07B-5cerA:
18.3		 3q07B-5cerA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 5cer BD3460
(Bdellovibrio
bacteriovorus) 		4 / 8 ALA B 112
ILE B 116
LEU B 100
ALA B 138
 None
 0.67A 3r9tA-5cerB:
undetectable		 3r9tA-5cerB:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 12 ALA A  57
SER A 239
ASN A 241
LYS A 345
THR A 346
GLY A 347
 None
 0.30A 3sh8A-5cerA:
18.6		 3sh8A-5cerA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 12 ALA A  57
LYS A  61
SER A 239
ASN A 241
LYS A 345
GLY A 347
 None
 0.30A 3sh8B-5cerA:
18.8		 3sh8B-5cerA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 5cer BD0816
BD3460
(Bdellovibrio
bacteriovorus;
Bdellovibrio
bacteriovorus) 		3 / 3 LYS B 214
SER A 402
GLN B 210
 None
 1.29A 3si7A-5cerB:
undetectable		 3si7A-5cerB:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 12 PHE A 334
ASN A 333
GLY A 336
ALA A 386
GLY A 384
 None
 1.18A 3v3oA-5cerA:
undetectable		 3v3oA-5cerA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWQ_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 12 ALA A  57
PHE A 274
ASN A 291
GLY A 347
ILE A  59
 None
 1.42A 3vwqA-5cerA:
12.0		 3vwqA-5cerA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWR_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 11 ALA A  57
PHE A 274
ASN A 291
GLY A 347
ILE A  59
 None
 1.42A 3vwrA-5cerA:
12.7		 3vwrA-5cerA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 11 PHE A 334
ASN A 333
GLY A 336
ALA A 386
GLY A 384
 None
 1.28A 4a6nA-5cerA:
undetectable		 4a6nA-5cerA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		4 / 8 SER A 358
GLU A 365
ILE A  69
VAL A  74
 None
 0.88A 4dx7B-5cerA:
undetectable		 4dx7B-5cerA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		9 / 12 ALA A  58
LYS A  61
SER A 239
ASN A 241
THR A 330
LYS A 345
THR A 346
GLY A 347
THR A 348
 None
 0.44A 4euzA-5cerA:
17.4		 4euzA-5cerA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 10 SER A 239
ASN A 241
LYS A 345
THR A 346
GLY A 347
ALA A  57
 None
 1.42A 4fh2A-5cerA:
19.4		 4fh2A-5cerA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 12 ASN A 306
LEU A  66
VAL A  62
ILE A  63
LEU A  56
 None
 1.23A 4k36A-5cerA:
undetectable		 4k36A-5cerA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 12 ASN A 306
LEU A  66
VAL A  62
ILE A  63
LEU A  56
 None
 1.20A 4k36B-5cerA:
undetectable		 4k36B-5cerA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 12 ALA A  57
SER A 239
ASN A 241
LYS A 345
THR A 346
GLY A 347
 None
 0.29A 4n9kA-5cerA:
18.8		 4n9kA-5cerA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 12 ALA A  57
SER A 239
ASN A 241
LYS A 345
THR A 346
GLY A 347
 None
 0.33A 4n9kB-5cerA:
18.7		 4n9kB-5cerA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P68_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 11 ILE A 243
SER A 109
ARG A 234
ILE A 103
THR A 149
 None
 1.18A 4p68A-5cerA:
undetectable		 4p68A-5cerA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 12 ASN A 241
THR A 330
LYS A 345
THR A 346
GLY A 347
 None
 0.29A 4pm5A-5cerA:
18.3		 4pm5A-5cerA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 12 LYS A  61
ASN A 241
THR A 330
LYS A 345
GLY A 347
 None
 0.35A 4pm7A-5cerA:
18.4		 4pm7A-5cerA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 12 LYS A  61
SER A 239
ASN A 241
LYS A 345
GLY A 347
 None
 0.71A 4pm7A-5cerA:
18.4		 4pm7A-5cerA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 12 ASN A 241
THR A 330
LYS A 345
THR A 346
GLY A 347
 None
 0.32A 4pm9A-5cerA:
18.3		 4pm9A-5cerA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 12 SER A 239
ASN A 241
LYS A 345
THR A 346
GLY A 347
ALA A  57
 None
 1.48A 4pm9A-5cerA:
18.3		 4pm9A-5cerA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		3 / 3 GLY A 403
PRO A 404
ALA A 338
 None
 0.51A 4qn9B-5cerA:
undetectable		 4qn9B-5cerA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		4 / 7 GLU A 365
SER A 358
ILE A 343
VAL A 322
 None
 1.09A 4tvtA-5cerA:
undetectable		 4tvtA-5cerA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		3 / 4 ARG A 401
GLY A 364
GLU A 363
 None
 0.63A 4z2dB-5cerA:
undetectable
4z2dC-5cerA:
undetectable		 4z2dB-5cerA:
21.59
4z2dC-5cerA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 5cer BD3460
(Bdellovibrio
bacteriovorus) 		4 / 8 LEU B 134
ASN B 141
ALA B 138
GLU B 113
 None
 0.88A 4zbqA-5cerB:
undetectable		 4zbqA-5cerB:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DWK_C_ACTC207_0
(DIACYLGLYCEROL
KINASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		4 / 5 GLU A 141
ALA A 139
GLU A 140
ASN A 107
 None
 1.37A 5dwkC-5cerA:
undetectable		 5dwkC-5cerA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 12 ALA A  57
SER A 239
ASN A 241
LYS A 345
GLY A 347
 None
 0.31A 5ghyA-5cerA:
18.4		 5ghyA-5cerA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 12 ALA A  57
SER A 239
ASN A 241
LYS A 345
GLY A 347
 None
 0.31A 5ghyB-5cerA:
18.6		 5ghyB-5cerA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 11 ALA A  57
SER A 239
ASN A 241
LYS A 345
THR A 346
GLY A 347
 None
 0.32A 5ghzA-5cerA:
18.7		 5ghzA-5cerA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 10 ALA A  57
SER A 239
ASN A 241
LYS A 345
THR A 346
GLY A 347
 None
 0.29A 5ghzB-5cerA:
18.7		 5ghzB-5cerA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		4 / 8 ARG A 144
GLY A 105
LEU A 135
ASN A 165
 None
 1.02A 5hwaA-5cerA:
undetectable		 5hwaA-5cerA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		4 / 7 LEU A 112
THR A 128
ASP A 130
LEU A 423
 None
 1.06A 5jq7B-5cerA:
undetectable		 5jq7B-5cerA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_D_CCSD14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 5cer BD0816
BD3460
(Bdellovibrio
bacteriovorus;
Bdellovibrio
bacteriovorus) 		5 / 12 PHE B 182
GLY A 335
GLY B 175
VAL B 171
THR B 176
 None
 1.35A 5o4yD-5cerB:
undetectable
5o4yE-5cerB:
undetectable		 5o4yD-5cerB:
8.00
5o4yE-5cerB:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 12 SER A 239
THR A 330
LYS A 345
THR A 346
GLY A 347
THR A 348
 None
 0.38A 6b5yB-5cerA:
17.8		 6b5yB-5cerA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 12 SER A 239
THR A 330
LYS A 345
THR A 346
GLY A 347
THR A 348
 None
 0.46A 6b5yD-5cerA:
17.7		 6b5yD-5cerA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 12 SER A 239
THR A 330
LYS A 345
THR A 346
GLY A 347
THR A 348
 None
 0.28A 6b68B-5cerA:
17.8		 6b68B-5cerA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 12 SER A 239
THR A 330
LYS A 345
GLY A 347
THR A 348
 None
 0.31A 6b68D-5cerA:
17.8		 6b68D-5cerA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 12 SER A 239
THR A 330
LYS A 345
THR A 346
GLY A 347
THR A 348
 None
 0.32A 6b69A-5cerA:
17.7
6b69B-5cerA:
17.8		 6b69A-5cerA:
11.61
6b69B-5cerA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 12 SER A 239
THR A 330
LYS A 345
THR A 346
GLY A 347
THR A 348
 None
 0.33A 6b69D-5cerA:
17.6		 6b69D-5cerA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 12 SER A 239
THR A 330
LYS A 345
THR A 346
GLY A 347
THR A 348
 None
 0.31A 6b6aB-5cerA:
17.8		 6b6aB-5cerA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 12 SER A 239
LYS A 345
THR A 346
GLY A 347
THR A 348
 None
 0.19A 6b6aD-5cerA:
17.8		 6b6aD-5cerA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 12 SER A 239
LYS A 345
THR A 346
GLY A 347
THR A 348
 None
 0.33A 6b6cA-5cerA:
17.8		 6b6cA-5cerA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 12 SER A 239
THR A 330
LYS A 345
THR A 346
GLY A 347
THR A 348
 None
 0.64A 6b6dA-5cerA:
17.6		 6b6dA-5cerA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 12 ILE A 145
SER A 239
THR A 330
LYS A 345
THR A 346
GLY A 347
 None
 1.33A 6b6eA-5cerA:
17.6		 6b6eA-5cerA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 12 SER A 239
THR A 330
LYS A 345
THR A 346
GLY A 347
THR A 348
 None
 0.32A 6b6eA-5cerA:
17.6		 6b6eA-5cerA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 12 SER A 239
LYS A 345
THR A 346
GLY A 347
THR A 348
 None
 0.44A 6b6fA-5cerA:
17.6		 6b6fA-5cerA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		6 / 12 ALA A  58
SER A 239
ASN A 241
THR A 330
LYS A 345
GLY A 347
 None
 0.25A 6c79A-5cerA:
18.1		 6c79A-5cerA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5cer BD0816
BD3460
(Bdellovibrio
bacteriovorus;
Bdellovibrio
bacteriovorus) 		3 / 3 GLN A 396
TYR B 174
ASN A 399
 None
 1.02A 6dwdC-5cerA:
undetectable		 6dwdC-5cerA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		4 / 8 ILE A 103
THR A  65
VAL A  62
SER A 278
 None
 0.93A 6fbvC-5cerA:
undetectable		 6fbvC-5cerA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 5cer BD0816
BD3460
(Bdellovibrio
bacteriovorus) 		5 / 12 THR A 346
GLY A 347
GLY A 335
ASN B 106
ASN A 350
 None
 1.16A 6gngA-5cerA:
undetectable		 6gngA-5cerA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLO_A_GBQA1501_1
(SUBSTANCE-P
RECEPTOR,GLGA
GLYCOGEN
SYNTHASE,SUBSTANCE-P
RECEPTOR)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		5 / 9 ASN A 337
ILE A 390
GLU A  45
VAL A  32
ILE A 370
 None
 1.18A 6hloA-5cerA:
undetectable		 6hloA-5cerA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_A_AM2A301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5cer BD0816
(Bdellovibrio
bacteriovorus) 		4 / 8 HIS A  83
HIS A  78
ASP A 130
GLU A 131
 None
 1.19A 6mn4A-5cerA:
undetectable		 6mn4A-5cerA:
20.95