SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ces'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 5ces PA0618
(Pseudomonas
aeruginosa) 		6 / 12 LEU A 233
ALA A 229
VAL A 261
LEU A 214
ALA A 212
VAL A 210
 None
 1.35A 1sn5B-5cesA:
undetectable
1sn5D-5cesA:
undetectable		 1sn5B-5cesA:
23.26
1sn5D-5cesA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 5ces PA0618
(Pseudomonas
aeruginosa) 		4 / 5 PRO A 269
VAL A 210
GLY A 291
VAL A 264
 None
 1.11A 6ak3B-5cesA:
undetectable		 6ak3B-5cesA:
28.57