SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cfc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5cfc VP1
(Cardiovirus
B) 		4 / 5 TYR A  37
TYR A 243
PHE A 122
PRO A 121
 None
 1.18A 1dfoB-5cfcA:
undetectable		 1dfoB-5cfcA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5cfc VP1
(Cardiovirus
B) 		4 / 5 TYR A  37
TYR A 243
PHE A 122
PRO A 121
 None
 1.18A 1dfoA-5cfcA:
undetectable		 1dfoA-5cfcA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5cfc VP1
(Cardiovirus
B) 		4 / 5 TYR A  37
TYR A 243
PHE A 122
PRO A 121
 None
 1.18A 1dfoD-5cfcA:
undetectable		 1dfoD-5cfcA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5cfc VP1
(Cardiovirus
B) 		4 / 5 TYR A  37
TYR A 243
PHE A 122
PRO A 121
 None
 1.18A 1dfoC-5cfcA:
undetectable		 1dfoC-5cfcA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_1
(HMG-COA REDUCTASE)		 5cfc VP3
(Cardiovirus
B) 		5 / 9 ASN B 110
LEU B  95
ALA B  99
LEU B  85
LEU B 220
 None
 1.48A 1hwiA-5cfcB:
undetectable		 1hwiA-5cfcB:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5cfc VP1
(Cardiovirus
B) 		4 / 6 VAL A 239
LEU A  46
PHE A 188
MET A 175
 None
 0.92A 1wrlB-5cfcA:
undetectable		 1wrlB-5cfcA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_B_BEZB194_0
(PUTATIVE KINASE)		 5cfc VP3
(Cardiovirus
B) 		4 / 5 PRO B 168
ILE B 166
ARG B 172
ASP B 185
 None
 1.43A 2rhmB-5cfcB:
undetectable		 2rhmB-5cfcB:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5cfc VP1
(Cardiovirus
B) 		4 / 6 TYR A  37
TYR A 243
PHE A 122
PRO A 121
 None
 1.20A 2vmyA-5cfcA:
undetectable		 2vmyA-5cfcA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 5cfc VP3
(Cardiovirus
B) 		5 / 10 PHE B 115
GLY B 123
PHE B 125
LEU B  78
THR B  73
 None
 1.39A 3a3yA-5cfcB:
undetectable		 3a3yA-5cfcB:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_1
(PROTEASE)		 5cfc VP1
VP3
(Cardiovirus
B) 		5 / 12 LEU B 209
ALA A   5
ASP A   3
THR B 116
VAL B 114
 None
 0.82A 3gguA-5cfcB:
undetectable		 3gguA-5cfcB:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 5cfc VP1
VP3
(Cardiovirus
B;
Cardiovirus
B) 		3 / 3 ASP A   3
ASN B 156
SER A  11
 None
 1.01A 3lsfB-5cfcA:
undetectable
3lsfE-5cfcA:
undetectable		 3lsfB-5cfcA:
20.49
3lsfE-5cfcA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5cfc VP1
VP3
(Cardiovirus
B) 		4 / 8 GLU A   6
ILE B 127
VAL B 190
PHE B 125
 None
 0.95A 4dx7B-5cfcA:
undetectable		 4dx7B-5cfcA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 5cfc VP3
(Cardiovirus
B) 		4 / 6 PHE B 161
THR B 162
TYR B 111
TYR B 105
 None
 1.25A 5lrbA-5cfcB:
undetectable		 5lrbA-5cfcB:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 5cfc VP1
(Cardiovirus
B) 		4 / 7 THR A 195
LEU A  69
VAL A 239
GLN A 112
 None
 1.04A 5tudA-5cfcA:
undetectable		 5tudA-5cfcA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5cfc VP1
VP3
(Cardiovirus
B;
Cardiovirus
B) 		3 / 3 LYS A   1
ASN B 160
SER A  11
 None
 1.08A 5yw0A-5cfcA:
undetectable		 5yw0A-5cfcA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5cfc VP1
VP3
(Cardiovirus
B;
Cardiovirus
B) 		3 / 3 LYS A   7
ASN A   4
SER B 158
 None
 1.23A 5yw0A-5cfcA:
undetectable		 5yw0A-5cfcA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 5cfc VP1
(Cardiovirus
B) 		3 / 3 PHE A  35
ARG A  32
GLN A  30
 None
 1.16A 6g1pB-5cfcA:
undetectable		 6g1pB-5cfcA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_2
(-)		 5cfc VP3
(Cardiovirus
B) 		4 / 8 VAL B  83
TYR B 129
ASN B 110
CYH B  48
 None
 1.27A 6gneB-5cfcB:
undetectable		 6gneB-5cfcB:
19.13