SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cff'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 5cff STAUFEN
(Drosophila
melanogaster) 		4 / 6 LEU E 961
LEU E 962
LEU E1012
LEU E1015
 None
 1.04A 3q1eA-5cffE:
undetectable
3q1eC-5cffE:
undetectable		 3q1eA-5cffE:
19.66
3q1eC-5cffE:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5V_A_ACTA511_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5cff STAUFEN
(Drosophila
melanogaster) 		4 / 4 ASN E 967
PHE E 968
SER E 969
GLN E1004
 None
 1.09A 3v5vA-5cffE:
undetectable		 3v5vA-5cffE:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZPH_A_PRLA501_0
(ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
ENDOTHELIAL PAS
DOMAIN-CONTAINING
PROTEIN 1)		 5cff STAUFEN
(Drosophila
melanogaster) 		4 / 7 VAL E 983
LEU E 985
SER E 986
GLU E 965
 None
 0.77A 4zphA-5cffE:
undetectable
4zphB-5cffE:
undetectable		 4zphA-5cffE:
13.45
4zphB-5cffE:
12.03