SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cfi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJQ_B_SAMB200_0 (METHIONINE REPRESSOR)	5cfi	BIS(5'-NUCLEOSYL)-TE TRAPHOSPHATASE (DIADENOSINE TETRAPHOSPHATASE), PUTATIVE (Plasmodium falciparum)	5 / 11	GLU A 126 GLY A 123 LEU A 85 LEU A 132 PRO A 133	None	1.26A	1mjqA-5cfiA: undetectable 1mjqB-5cfiA: undetectable	1mjqA-5cfiA: 18.54 1mjqB-5cfiA: 18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZBU_D_ADND504_1 (UNCHARACTERIZED CONSERVED PROTEIN)	5cfi	BIS(5'-NUCLEOSYL)-TE TRAPHOSPHATASE (DIADENOSINE TETRAPHOSPHATASE), PUTATIVE (Plasmodium falciparum)	3 / 3	PHE A 30 ASN A 28 PHE A 32	None	1.02A	2zbuD-5cfiA: undetectable	2zbuD-5cfiA: 21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MI4_C_SPMC201_1 (SPERMIDINE N1-ACETYLTRANSFERASE)	5cfi	BIS(5'-NUCLEOSYL)-TE TRAPHOSPHATASE (DIADENOSINE TETRAPHOSPHATASE), PUTATIVE (Plasmodium falciparum)	4 / 7	TYR A 119 ASN A 106 GLU A 31 GLU A 107	None	1.29A	4mi4A-5cfiA: undetectable 4mi4C-5cfiA: undetectable	4mi4A-5cfiA: 16.50 4mi4C-5cfiA: 16.50

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MJQ_B_SAMB200_0","METHIONINE REPRESSOR","5cfi","BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE (DIADENOSINE TETRAPHOSPHATASE), PUTATIVE","Plasmodium falciparum",5,"GLU A 126;GLY A 123;LEU A  85;LEU A 132;PRO A 133","None","1.26A","1mjqA-5cfiA:undetectable;1mjqB-5cfiA:undetectable","1mjqA-5cfiA:18.54;1mjqB-5cfiA:18.54"],["2ZBU_D_ADND504_1","UNCHARACTERIZED CONSERVED PROTEIN","5cfi","BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE (DIADENOSINE TETRAPHOSPHATASE), PUTATIVE","Plasmodium falciparum",3,"PHE A  30;ASN A  28;PHE A  32","None","1.02A","2zbuD-5cfiA:undetectable","2zbuD-5cfiA:21.79"],["4MI4_C_SPMC201_1","SPERMIDINE N1-ACETYLTRANSFERASE;SPERMIDINE N1-ACETYLTRANSFERASE","5cfi","BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE (DIADENOSINE TETRAPHOSPHATASE), PUTATIVE","Plasmodium falciparum",4,"TYR A 119;ASN A 106;GLU A  31;GLU A 107","None","1.29A","4mi4A-5cfiA:undetectable;4mi4C-5cfiA:undetectable","4mi4A-5cfiA:16.50;4mi4C-5cfiA:16.50"]]