SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cfn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 5cfn STIMULATOR OF
INTERFERON GENES
(Nematostella
vectensis) 		4 / 4 ASP A 310
LEU A 305
LEU A 308
LEU A 306
 None
 1.40A 1u18A-5cfnA:
undetectable		 1u18A-5cfnA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5cfn STIMULATOR OF
INTERFERON GENES
(Nematostella
vectensis) 		5 / 12 LEU A 339
LEU A 211
GLU A 300
TYR A 349
ALA A 302
 None
 1.17A 2bm9A-5cfnA:
undetectable		 2bm9A-5cfnA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 5cfn STIMULATOR OF
INTERFERON GENES
(Nematostella
vectensis) 		4 / 8 ALA A 302
ILE A 238
LEU A 305
ALA A 199
 None
 0.75A 3r9tA-5cfnA:
undetectable		 3r9tA-5cfnA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ4_B_IMNB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5cfn STIMULATOR OF
INTERFERON GENES
(Nematostella
vectensis) 		5 / 10 TYR A 253
VAL A 352
ILE A 236
LEU A 306
LEU A 305
 None
 1.22A 4jq4B-5cfnA:
undetectable		 4jq4B-5cfnA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 5cfn STIMULATOR OF
INTERFERON GENES
(Nematostella
vectensis) 		5 / 9 ILE A 236
TRP A 244
GLN A 336
LEU A 305
LEU A 306
 None
 1.43A 5fhzB-5cfnA:
undetectable		 5fhzB-5cfnA:
17.14