SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cg0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		4 / 8 THR A 184
GLY A 243
CYH A 242
THR A 322
 None
 0.81A 1h4oB-5cg0A:
undetectable		 1h4oB-5cg0A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		5 / 12 LEU A  93
ALA A 443
MET A 442
MET A 425
ARG A 490
 None
 1.23A 1kt4A-5cg0A:
undetectable		 1kt4A-5cg0A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		5 / 12 LEU A  93
ALA A 443
MET A 442
MET A 425
ARG A 490
 None
 1.22A 1kt5A-5cg0A:
undetectable		 1kt5A-5cg0A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		4 / 8 THR A 184
GLY A 243
CYH A 242
THR A 322
 None
 0.78A 1oc3A-5cg0A:
undetectable		 1oc3A-5cg0A:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		4 / 5 TYR A 441
TYR A 483
ILE A 486
GLY A 440
 None
 1.32A 2du8J-5cg0A:
undetectable		 2du8J-5cg0A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_A_NCAA1501_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		4 / 7 PHE A 234
ARG A 232
ALA A 168
ARG A 169
 None
 1.15A 2e5dA-5cg0A:
3.0
2e5dB-5cg0A:
2.8		 2e5dA-5cg0A:
24.09
2e5dB-5cg0A:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		4 / 5 ASP A 127
LEU A 130
LYS A 131
ARG A 178
 None
 1.11A 2gj5A-5cg0A:
undetectable		 2gj5A-5cg0A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_1
(PROTEASE)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		5 / 11 LEU A 389
ALA A 282
GLY A 321
ILE A 279
PRO A 393
 None
 1.09A 2o4pA-5cg0A:
undetectable		 2o4pA-5cg0A:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		5 / 12 ILE A  65
ALA A  74
GLY A 455
SER A  77
ASN A  70
 None
 1.13A 2okcA-5cg0A:
undetectable		 2okcA-5cg0A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		5 / 12 ILE A  65
ALA A  74
GLY A 455
SER A  77
ASN A  70
 None
 1.15A 2okcB-5cg0A:
undetectable		 2okcB-5cg0A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA803_0
(FERROCHELATASE)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		4 / 5 LEU A 145
PRO A 146
LEU A 149
ILE A 160
 None
 0.82A 2qd4A-5cg0A:
undetectable		 2qd4A-5cg0A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		5 / 11 ASN A 186
GLU A 187
TYR A 331
GLU A 399
TRP A 444
 None
TRS  A 603 (-2.7A)
TRS  A 603 (-4.7A)
TRS  A 603 (-2.8A)
TRS  A 603 ( 4.2A)
 0.86A 2v3dB-5cg0A:
2.5		 2v3dB-5cg0A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		5 / 12 LEU A 219
VAL A 220
SER A 358
PHE A 251
ASN A 249
 None
 1.48A 2y00B-5cg0A:
undetectable		 2y00B-5cg0A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		5 / 12 LEU A 219
VAL A 220
SER A 358
PHE A 251
ASN A 249
 None
 1.46A 2y01B-5cg0A:
undetectable		 2y01B-5cg0A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		5 / 11 THR A 184
GLY A 243
PHE A 280
PRO A 188
ILE A 279
 None
 1.12A 2y7kA-5cg0A:
undetectable		 2y7kA-5cg0A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_B_SALB1304_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		5 / 10 THR A 184
GLY A 243
PHE A 280
PRO A 188
ILE A 279
 None
 1.21A 2y7kB-5cg0A:
0.0		 2y7kB-5cg0A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		5 / 12 THR A 184
GLY A 243
PHE A 280
PRO A 188
ILE A 279
 None
 1.33A 2y7kC-5cg0A:
undetectable		 2y7kC-5cg0A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1000_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		5 / 10 THR A 184
GLY A 243
PHE A 280
PRO A 188
ILE A 279
 None
 1.15A 2y7pA-5cg0A:
undetectable		 2y7pA-5cg0A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		4 / 7 PHE A 182
GLY A 240
ASP A 177
ARG A 178
 None
 1.17A 3aruA-5cg0A:
11.0		 3aruA-5cg0A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		4 / 8 TYR A 141
ASN A 186
PHE A 460
TRP A 444
 None
None
TRS  A 603 (-4.1A)
TRS  A 603 ( 4.2A)
 1.45A 3bjwD-5cg0A:
undetectable		 3bjwD-5cg0A:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		3 / 3 GLU A 190
GLU A 187
TRP A 371
 TRS  A 603 ( 4.9A)
TRS  A 603 (-2.7A)
None
 1.33A 3hrdA-5cg0A:
undetectable
3hrdE-5cg0A:
undetectable
3hrdF-5cg0A:
undetectable		 3hrdA-5cg0A:
21.83
3hrdE-5cg0A:
21.83
3hrdF-5cg0A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		3 / 3 TYR A  78
ASP A  76
ASP A  72
 None
 0.91A 3ou7B-5cg0A:
undetectable		 3ou7B-5cg0A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		4 / 7 PRO A 203
ILE A  53
GLN A 150
GLY A 154
 None
 1.01A 4a3uB-5cg0A:
12.8		 4a3uB-5cg0A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		4 / 7 GLY A  42
ASP A  72
GLY A  71
HIS A  59
 None
 0.91A 4c5nA-5cg0A:
undetectable		 4c5nA-5cg0A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		4 / 8 GLY A  42
ASP A  72
GLY A  71
HIS A  59
 None
 0.84A 4c5nC-5cg0A:
undetectable		 4c5nC-5cg0A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		4 / 4 LEU A 145
PRO A 146
LEU A 149
ILE A 160
 None
 0.88A 4f4dB-5cg0A:
undetectable		 4f4dB-5cg0A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		4 / 6 PRO A 146
ILE A 160
TYR A 141
PHE A 155
 None
 1.14A 4g10A-5cg0A:
undetectable		 4g10A-5cg0A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		4 / 6 SER A  77
VAL A 465
THR A 473
ARG A 474
 None
 1.35A 4lnxA-5cg0A:
undetectable		 4lnxA-5cg0A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		3 / 3 ASP A 144
TRP A 444
SER A  99
 None
TRS  A 603 ( 4.2A)
None
 0.98A 4lrhB-5cg0A:
undetectable		 4lrhB-5cg0A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		3 / 3 ASP A 144
TRP A 444
SER A  99
 None
TRS  A 603 ( 4.2A)
None
 1.07A 4lrhF-5cg0A:
undetectable		 4lrhF-5cg0A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZD_A_RBFA201_1
(TRANSCRIPTIONAL
REGULATOR, PADR-LIKE
FAMILY)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		4 / 4 ALA A 168
VAL A 171
TRP A 102
ASP A 144
 None
 1.03A 4zzdA-5cg0A:
0.0		 4zzdA-5cg0A:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		3 / 3 LEU A 446
TYR A 125
SER A  77
 None
 0.89A 5iktA-5cg0A:
undetectable		 5iktA-5cg0A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		4 / 7 ILE A 134
THR A 135
MET A 129
MET A 442
 None
 1.46A 5ljcA-5cg0A:
undetectable		 5ljcA-5cg0A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		4 / 4 GLY A 252
PRO A 253
VAL A 336
ARG A 268
 None
 1.24A 5uunA-5cg0A:
0.0
5uunB-5cg0A:
undetectable		 5uunA-5cg0A:
20.72
5uunB-5cg0A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_0
(REGULATORY PROTEIN
TETR)		 5cg0 BETA-GLUCOSIDASE
(Spodoptera
frugiperda) 		5 / 12 MET A  88
ALA A  95
VAL A 179
TYR A 122
THR A 139
 None
 1.46A 5vlmD-5cg0A:
undetectable		 5vlmD-5cg0A:
19.69