SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cgy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5cgy HEAVY CHAIN OF FAB
(Homo
sapiens) 		5 / 12 GLY H  89
ILE H  34
GLY H 118
PHE H  64
THR H  91
 None
 1.06A 4zdyA-5cgyH:
undetectable		 4zdyA-5cgyH:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5cgy HEAVY CHAIN OF FAB
(Homo
sapiens) 		5 / 12 GLY H  89
ILE H  34
GLY H 118
PHE H  64
THR H  91
 None
 1.04A 5eskA-5cgyH:
undetectable		 5eskA-5cgyH:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5cgy HEAVY CHAIN OF FAB
(Homo
sapiens) 		5 / 12 GLY H  89
LEU H  81
ILE H  34
PHE H  64
THR H  91
 None
 1.12A 5eskA-5cgyH:
undetectable		 5eskA-5cgyH:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5cgy HEAVY CHAIN OF FAB
(Homo
sapiens) 		5 / 12 GLY H  89
ILE H  34
GLY H 118
PHE H  64
THR H  91
 None
 1.04A 5eslA-5cgyH:
undetectable		 5eslA-5cgyH:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 5cgy HEAVY CHAIN OF FAB
(Homo
sapiens) 		4 / 4 LEU H 152
LEU H 203
GLY H 204
GLU H 226
 None
 1.26A 5hhjA-5cgyH:
undetectable		 5hhjA-5cgyH:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_0
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5cgy HEAVY CHAIN OF FAB
(Homo
sapiens) 		5 / 12 GLY H  89
ILE H  34
GLY H 118
PHE H  64
THR H  91
 None
 1.12A 6e8qA-5cgyH:
undetectable		 6e8qA-5cgyH:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I0Y_A_TRPA3001_0
(23S RIBOSOMAL RNA
TRYPTOPHANASE OPERON
LEADER PEPTIDE)		 5cgy HEAVY CHAIN OF FAB
(Homo
sapiens) 		3 / 3 TRP H  50
ILE H  51
ASP H  52
 None
 0.79A 6i0y7-5cgyH:
undetectable		 6i0y7-5cgyH:
5.29