SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ch6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		 5ch6 FRIGIDA
(Vitis
vinifera) 		4 / 8 MET A 350
GLU A 381
GLU A 375
ASP A 374
 None
 1.24A 1dtlA-5ch6A:
undetectable		 1dtlA-5ch6A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5ch6 FRIGIDA
(Vitis
vinifera) 		4 / 7 PHE A 319
ALA A 349
TYR A 346
ILE A 373
 None
 1.13A 1oniA-5ch6A:
undetectable
1oniB-5ch6A:
undetectable		 1oniA-5ch6A:
19.86
1oniB-5ch6A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5ch6 FRIGIDA
(Vitis
vinifera) 		4 / 7 TYR A 346
ILE A 373
PHE A 319
ALA A 349
 None
 1.06A 1oniG-5ch6A:
undetectable
1oniI-5ch6A:
undetectable		 1oniG-5ch6A:
19.86
1oniI-5ch6A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 5ch6 FRIGIDA
(Vitis
vinifera) 		5 / 11 LEU A 188
LEU A 148
VAL A 144
LEU A 134
CYH A 161
 None
 0.86A 2uxoB-5ch6A:
undetectable		 2uxoB-5ch6A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAU_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 5ch6 FRIGIDA
(Vitis
vinifera) 		5 / 12 ILE A 232
LEU A 188
ALA A 185
ILE A 267
LEU A 239
 None
 0.99A 3dauA-5ch6A:
undetectable		 3dauA-5ch6A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)		 5ch6 FRIGIDA
(Vitis
vinifera) 		5 / 6 LYS A 351
LEU A 347
LYS A 376
LEU A 380
GLU A 381
 None
 1.30A 3h5gB-5ch6A:
undetectable
3h5gC-5ch6A:
undetectable		 3h5gB-5ch6A:
8.30
3h5gC-5ch6A:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPS_A_CHDA211_0
(CMER)		 5ch6 FRIGIDA
(Vitis
vinifera) 		5 / 10 LEU A 278
PHE A 310
ALA A 301
PHE A 304
GLY A 305
 None
 1.25A 3qpsA-5ch6A:
undetectable		 3qpsA-5ch6A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 5ch6 FRIGIDA
(Vitis
vinifera) 		4 / 5 ILE A 246
PRO A 247
SER A 243
GLY A 245
 None
 1.13A 3tkdB-5ch6A:
undetectable		 3tkdB-5ch6A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 5ch6 FRIGIDA
(Vitis
vinifera) 		4 / 5 ILE A 246
PRO A 247
SER A 243
GLY A 245
 None
 1.15A 3tkdA-5ch6A:
undetectable		 3tkdA-5ch6A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5ch6 FRIGIDA
(Vitis
vinifera) 		4 / 6 VAL A 144
LEU A 140
LEU A 126
PHE A 244
 None
 1.10A 4o1zA-5ch6A:
undetectable		 4o1zA-5ch6A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSY_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5ch6 FRIGIDA
(Vitis
vinifera) 		5 / 12 ILE A 232
LEU A 188
ALA A 185
ILE A 267
LEU A 239
 None
 0.94A 4psyA-5ch6A:
undetectable		 4psyA-5ch6A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_D_NOVD2000_1
(DNA GYRASE SUBUNIT B)		 5ch6 FRIGIDA
(Vitis
vinifera) 		5 / 12 ASN A 252
ARG A 217
ILE A 246
PRO A 247
ASP A 210
 None
 1.20A 4uroD-5ch6A:
undetectable		 4uroD-5ch6A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 5ch6 FRIGIDA
(Vitis
vinifera) 		3 / 3 TYR A 346
LYS A 328
LYS A 324
 None
 1.23A 5dbyA-5ch6A:
undetectable		 5dbyA-5ch6A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_0
(METHYLTRANSFERASE)		 5ch6 FRIGIDA
(Vitis
vinifera) 		5 / 12 LEU A 239
ALA A 242
VAL A 241
GLU A 266
ALA A 234
 None
 1.12A 5n5dB-5ch6A:
undetectable		 5n5dB-5ch6A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_F_SAMF501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5ch6 FRIGIDA
(Vitis
vinifera) 		5 / 10 LEU A 240
GLY A 245
VAL A 158
LEU A 159
ALA A 209
 None
 1.08A 5o96E-5ch6A:
undetectable
5o96F-5ch6A:
undetectable		 5o96E-5ch6A:
20.41
5o96F-5ch6A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11803_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)		 5ch6 FRIGIDA
(Vitis
vinifera) 		3 / 3 SER A 365
LYS A 366
SER A 369
 None
 0.70A 6az3P-5ch6A:
undetectable		 6az3P-5ch6A:
14.17