SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5che'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_A_FLPA1650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 5che PROTEIN FLUORESCENT
IN BLUE LIGHT,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 VAL E 270
LEU E 271
ILE E 290
GLY E 288
ALA E 289
 None
 0.83A 1cqeA-5cheE:
undetectable		 1cqeA-5cheE:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_B_FLPB2650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 5che PROTEIN FLUORESCENT
IN BLUE LIGHT,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 VAL E 270
LEU E 271
ILE E 290
GLY E 288
ALA E 289
 None
 0.83A 1cqeB-5cheE:
undetectable		 1cqeB-5cheE:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5che GLUTAMYL-TRNA
REDUCTASE-BINDING
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 4 ILE C 219
LEU C 229
VAL C 259
ILE C 261
 None
 0.93A 1fm6D-5cheC:
undetectable		 1fm6D-5cheC:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_B_FLPB2701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5che PROTEIN FLUORESCENT
IN BLUE LIGHT,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 VAL E 270
LEU E 271
ILE E 290
GLY E 288
ALA E 289
 None
 0.83A 2aylB-5cheE:
undetectable		 2aylB-5cheE:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5che PROTEIN FLUORESCENT
IN BLUE LIGHT,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 VAL E 270
LEU E 271
ILE E 290
GLY E 288
ALA E 289
 None
 0.92A 3kk6A-5cheE:
undetectable		 3kk6A-5cheE:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5che PROTEIN FLUORESCENT
IN BLUE LIGHT,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 11 VAL E 270
LEU E 271
ILE E 290
GLY E 288
ALA E 289
 None
 0.89A 3n8yA-5cheE:
undetectable		 3n8yA-5cheE:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_SALB900_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5che PROTEIN FLUORESCENT
IN BLUE LIGHT,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 VAL E 270
LEU E 271
ILE E 290
ALA E 289
 None
 0.82A 3n8yB-5cheE:
undetectable		 3n8yB-5cheE:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_B_FLPB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5che PROTEIN FLUORESCENT
IN BLUE LIGHT,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 VAL E 270
LEU E 271
ILE E 290
GLY E 288
ALA E 289
 None
 0.81A 3n8zB-5cheE:
undetectable		 3n8zB-5cheE:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 5che GLUTAMYL-TRNA
REDUCTASE-BINDING
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 ILE C 219
ILE C 261
LEU C 229
VAL C 233
 None
 0.86A 3ua5B-5cheC:
undetectable		 3ua5B-5cheC:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA505_0
(RNA POLYMERASE
3D-POL)		 5che GLUTAMYL-TRNA
REDUCTASE-BINDING
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 CYH C 104
ASN C 106
LYS C 162
 None
 1.25A 4k50A-5cheC:
undetectable		 4k50A-5cheC:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE502_0
(RNA POLYMERASE
3D-POL)		 5che PROTEIN FLUORESCENT
IN BLUE LIGHT,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 ARG E 248
LYS E 245
LYS E 244
 None
 1.40A 4k50E-5cheE:
undetectable		 4k50E-5cheE:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI506_0
(RNA POLYMERASE
3D-POL)		 5che PROTEIN FLUORESCENT
IN BLUE LIGHT,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 ARG E 248
LYS E 245
LYS E 244
 None
 1.40A 4k50I-5cheE:
undetectable		 4k50I-5cheE:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 5che GLUTAMYL-TRNA
REDUCTASE-BINDING
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 11 PRO C 101
VAL C  95
ALA C  94
SER C  72
SER C  73
 None
 1.09A 4mmaA-5cheC:
undetectable		 4mmaA-5cheC:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 5che GLUTAMYL-TRNA
REDUCTASE-BINDING
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 PRO C 101
VAL C  95
ALA C  94
SER C  72
SER C  73
 None
 0.92A 4mmdB-5cheC:
undetectable		 4mmdB-5cheC:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSE_C_HQEC1583_1
(UREASE SUBUNIT ALPHA)		 5che PROTEIN FLUORESCENT
IN BLUE LIGHT,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 ILE E 264
GLN E 255
CYH E 293
GLU E 296
 None
 1.46A 5fseC-5cheE:
undetectable		 5fseC-5cheE:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_A_CCSA14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 5che GLUTAMYL-TRNA
REDUCTASE-BINDING
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 6 PHE C  93
LEU C  77
ARG C  92
GLY C  90
 None
 1.13A 5o4yA-5cheC:
undetectable		 5o4yA-5cheC:
4.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_B_SAMB501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 5che GLUTAMYL-TRNA
REDUCTASE-BINDING
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ALA C  62
PRO C  61
LYS C 193
ASP C  98
GLY C  99
 None
 1.27A 5wwsB-5cheC:
undetectable		 5wwsB-5cheC:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 5che GLUTAMYL-TRNA
REDUCTASE-BINDING
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 LEU C 200
GLY C 272
SER C 276
PHE C 222
VAL C 208
 None
 1.36A 6a94A-5cheC:
undetectable		 6a94A-5cheC:
22.39