SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5chh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5chh ARAC FAMILY
TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		5 / 10 LEU A 150
ALA A  87
ILE A  91
GLY A  75
PHE A 208
 None
 1.35A 2b17A-5chhA:
undetectable		 2b17A-5chhA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 5chh ARAC FAMILY
TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		3 / 3 SER A 110
ASP A 116
ASP A 113
 None
 0.87A 3iv6A-5chhA:
undetectable		 3iv6A-5chhA:
24.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 5chh ARAC FAMILY
TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		3 / 3 SER A 110
ASP A 116
ASP A 113
 None
 0.83A 3iv6C-5chhA:
undetectable		 3iv6C-5chhA:
24.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC800_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 5chh ARAC FAMILY
TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		3 / 3 ASP A 268
ARG A 264
ALA A 267
 None
 0.69A 3mbgC-5chhA:
undetectable		 3mbgC-5chhA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 5chh ARAC FAMILY
TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		5 / 11 GLY A 229
GLU A 269
LEU A 266
ARG A 263
LEU A 255
 None
 1.15A 3ndvA-5chhA:
undetectable
3ndvB-5chhA:
undetectable		 3ndvA-5chhA:
24.34
3ndvB-5chhA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 5chh ARAC FAMILY
TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		3 / 3 TYR A  19
TYR A 134
GLU A  64
 None
 0.55A 3pfgA-5chhA:
undetectable		 3pfgA-5chhA:
25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5chh ARAC FAMILY
TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		4 / 8 ILE A 105
ASP A 118
ILE A 119
PHE A 189
 None
 0.74A 4acaC-5chhA:
undetectable		 4acaC-5chhA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5chh ARAC FAMILY
TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		4 / 8 ILE A 105
ASP A 118
ILE A 119
PHE A 189
 None
 0.75A 4acbC-5chhA:
undetectable		 4acbC-5chhA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5chh ARAC FAMILY
TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		5 / 10 PHE A  98
TYR A  66
LEU A  62
GLY A  59
ASP A 101
 None
 1.14A 4jx1B-5chhA:
undetectable		 4jx1B-5chhA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 5chh ARAC FAMILY
TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		5 / 12 VAL A 146
ILE A 119
VAL A 117
VAL A 115
LEU A 196
 None
 1.20A 4y0pA-5chhA:
undetectable		 4y0pA-5chhA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 5chh ARAC FAMILY
TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 136
LEU A 139
ALA A 140
PHE A 176
TYR A 172
 None
 1.19A 5k9dA-5chhA:
undetectable		 5k9dA-5chhA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5chh ARAC FAMILY
TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		3 / 3 GLU A  64
HIS A  65
ARG A  67
 None
 0.73A 5uunA-5chhA:
undetectable		 5uunA-5chhA:
22.41