SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5chn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5chn ANTIBODY 5M16 FAB
HEAVY CHAIN
(Homo
sapiens) 		4 / 6 LEU H 198
GLY H 199
ALA H 134
PRO H 135
 None
 0.44A 3huoA-5chnH:
undetectable		 3huoA-5chnH:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 5chn ANTIBODY 5M16 FAB
HEAVY CHAIN
(Homo
sapiens) 		4 / 7 PRO H  53
LEU H 109
THR H  51
ILE H  50
 None
 0.94A 3p50A-5chnH:
undetectable		 3p50A-5chnH:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 5chn ANTIBODY 5M16 FAB
HEAVY CHAIN
(Homo
sapiens) 		4 / 7 PRO H  53
LEU H 109
THR H  51
ILE H  50
 None
 0.93A 3p50B-5chnH:
undetectable		 3p50B-5chnH:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 5chn ANTIBODY 5M16 FAB
HEAVY CHAIN
(Homo
sapiens) 		4 / 7 PRO H  53
LEU H 109
THR H  51
ILE H  50
 None
 0.94A 3p50C-5chnH:
undetectable		 3p50C-5chnH:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_D_PFLD320_1
(GLR4197 PROTEIN)		 5chn ANTIBODY 5M16 FAB
HEAVY CHAIN
(Homo
sapiens) 		4 / 7 PRO H  53
LEU H 109
THR H  51
ILE H  50
 None
 0.93A 3p50D-5chnH:
undetectable		 3p50D-5chnH:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 5chn ANTIBODY 5M16 FAB
HEAVY CHAIN
(Homo
sapiens) 		4 / 7 PRO H  53
LEU H 109
THR H  51
ILE H  50
 None
 0.90A 3p50E-5chnH:
undetectable		 3p50E-5chnH:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 5chn ANTIBODY 5M16 FAB
HEAVY CHAIN
(Homo
sapiens) 		4 / 5 ASP H  85
SER H  88
VAL H 120
GLY H  15
 None
 1.07A 3rxhA-5chnH:
undetectable		 3rxhA-5chnH:
26.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 5chn ANTIBODY 5M16 FAB
HEAVY CHAIN
(Homo
sapiens) 		5 / 10 TYR H 185
LEU H 117
VAL H  18
LEU H  86
LEU H 179
 None
 1.18A 5ienB-5chnH:
undetectable		 5ienB-5chnH:
20.26