SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ci5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1AO8_A_MTXA170_2 (DIHYDROFOLATE REDUCTASE)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	4 / 4	TRP A 264 LEU A 33 ARG A 339 THR A 338	T6T A 501 (-2.9A) None None None	1.33A	1ao8A-5ci5A: 0.0	1ao8A-5ci5A: 18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DDR_A_MTXA200_1 (DIHYDROFOLATE REDUCTASE)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 12	ALA A 366 SER A 377 ILE A 376 LEU A 409 TYR A 198	None	1.02A	1ddrA-5ci5A: undetectable	1ddrA-5ci5A: 16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DHI_A_MTXA161_1 (DIHYDROFOLATE REDUCTASE)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 12	ALA A 366 SER A 377 ILE A 376 LEU A 409 TYR A 198	None	0.97A	1dhiA-5ci5A: undetectable	1dhiA-5ci5A: 16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DHJ_A_MTXA161_1 (DIHYDROFOLATE REDUCTASE)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 12	ALA A 366 SER A 377 ILE A 376 LEU A 409 TYR A 198	None	0.97A	1dhjA-5ci5A: undetectable	1dhjA-5ci5A: 16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DRA_A_MTXA161_1 (DIHYDROFOLATE REDUCTASE)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 12	ALA A 366 SER A 377 ILE A 376 LEU A 409 TYR A 198	None	0.97A	1draA-5ci5A: undetectable	1draA-5ci5A: 17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DRB_A_MTXA161_1 (DIHYDROFOLATE REDUCTASE)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 12	ALA A 366 SER A 377 ILE A 376 LEU A 409 TYR A 198	None	0.97A	1drbA-5ci5A: undetectable	1drbA-5ci5A: 16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I9G_A_SAMA301_1 (HYPOTHETICAL PROTEIN RV2118C)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	3 / 3	GLU A 244 HIS A 188 ASP A 134	None None T6T A 501 (-1.9A)	0.88A	1i9gA-5ci5A: undetectable	1i9gA-5ci5A: 21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RG7_A_MTXA161_1 (DIHYDROFOLATE REDUCTASE)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 12	ALA A 366 SER A 377 ILE A 376 LEU A 409 TYR A 198	None	0.96A	1rg7A-5ci5A: undetectable	1rg7A-5ci5A: 16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1U18_B_HSMB402_1 (NITROPHORIN 1)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	4 / 5	ASP A 82 GLU A 187 THR A 119 LEU A 295	T6T A 501 (-2.3A) None None None	1.03A	1u18B-5ci5A: undetectable	1u18B-5ci5A: 19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1U18_B_HSMB402_1 (NITROPHORIN 1)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	4 / 5	GLU A 187 THR A 119 LEU A 295 LEU A 83	None	1.04A	1u18B-5ci5A: undetectable	1u18B-5ci5A: 19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZZ1_C_SHHC2652_1 (HISTONE DEACETYLASE-LIKE AMIDOHYDROLASE)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 12	LEU A 33 GLY A 28 ASP A 134 GLY A 297 TYR A 132	None None T6T A 501 (-1.9A) T6T A 501 (-3.4A) T6T A 501 (-4.4A)	1.09A	1zz1C-5ci5A: undetectable	1zz1C-5ci5A: 22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DRC_A_MTXA161_1 (DIHYDROFOLATE REDUCTASE)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 12	ALA A 366 SER A 377 ILE A 376 LEU A 409 TYR A 198	None	0.95A	2drcA-5ci5A: undetectable	2drcA-5ci5A: 16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F80_B_017B301_1 (POL POLYPROTEIN)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 12	ALA A 312 ASP A 311 ASN A 308 PRO A 98 ILE A 302	None	1.00A	2f80A-5ci5A: undetectable	2f80A-5ci5A: 12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H42_C_VIAC903_2 (CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	3 / 3	ASN A 151 ILE A 169 MET A 258	None	0.71A	2h42C-5ci5A: undetectable	2h42C-5ci5A: 21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OIP_D_MTXD617_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 12	ALA A 81 LEU A 83 THR A 338 ILE A 112 LEU A 103	None	1.15A	2oipD-5ci5A: undetectable	2oipD-5ci5A: 20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2UVN_B_ECNB1406_1 (CYTOCHROME P450 130)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 11	PRO A 371 GLY A 85 LEU A 96 TYR A 127 VAL A 120	None	1.49A	2uvnB-5ci5A: undetectable	2uvnB-5ci5A: 21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B9L_A_AZZA1009_1 (SERUM ALBUMIN)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	4 / 8	GLU A 187 SER A 377 GLN A 381 VAL A 181	None	1.24A	3b9lA-5ci5A: 1.8	3b9lA-5ci5A: 21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DRC_A_MTXA161_1 (DIHYDROFOLATE REDUCTASE)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 12	ALA A 366 SER A 377 ILE A 376 LEU A 409 TYR A 198	None	0.96A	3drcA-5ci5A: undetectable	3drcA-5ci5A: 16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JZJ_A_ACRA405_1 (ACARBOSE/MALTOSE BINDING PROTEIN GACH)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 12	ARG A 136 ALA A 366 ASP A 82 TRP A 298 GLY A 84	T6T A 501 (-3.0A) None T6T A 501 (-2.3A) T6T A 501 (-3.5A) T6T A 501 ( 4.6A)	1.44A	3jzjA-5ci5A: 45.6	3jzjA-5ci5A: 29.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JZJ_A_ACRA405_1 (ACARBOSE/MALTOSE BINDING PROTEIN GACH)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 12	GLY A 58 ASP A 134 ASP A 245 GLY A 296 ARG A 367	None T6T A 501 (-1.9A) None T6T A 501 (-3.2A) T6T A 501 (-3.0A)	1.09A	3jzjA-5ci5A: 45.6	3jzjA-5ci5A: 29.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DFR_A_MTXA161_1 (DIHYDROFOLATE REDUCTASE)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 12	ALA A 366 SER A 377 ILE A 376 LEU A 409 TYR A 198	None	0.96A	4dfrA-5ci5A: undetectable	4dfrA-5ci5A: 16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KYK_B_IMNB300_1 (LACTOYLGLUTATHIONE LYASE)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 12	PHE A 196 ALA A 200 PHE A 225 LEU A 229 LEU A 138	None	1.25A	4kykA-5ci5A: undetectable 4kykB-5ci5A: undetectable	4kykA-5ci5A: 19.76 4kykB-5ci5A: 19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QI9_A_MTXA201_1 (DIHYDROFOLATE REDUCTASE)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 12	ALA A 366 SER A 377 ILE A 376 LEU A 409 TYR A 198	None	1.02A	4qi9A-5ci5A: undetectable	4qi9A-5ci5A: 16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QI9_B_MTXB201_1 (DIHYDROFOLATE REDUCTASE)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 12	ALA A 366 SER A 377 ILE A 376 LEU A 409 TYR A 198	None	1.00A	4qi9B-5ci5A: undetectable	4qi9B-5ci5A: 16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QI9_C_MTXC201_1 (DIHYDROFOLATE REDUCTASE)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 11	ALA A 366 SER A 377 ILE A 376 LEU A 409 TYR A 198	None	1.00A	4qi9C-5ci5A: undetectable	4qi9C-5ci5A: 16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QLE_B_FOLB201_0 (DIHYDROFOLATE REDUCTASE)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 11	ALA A 366 SER A 377 ILE A 376 LEU A 409 TYR A 198	None	1.01A	4qleB-5ci5A: undetectable	4qleB-5ci5A: 18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DPD_A_SAMA601_0 (PROTEIN LYSINE METHYLTRANSFERASE 1)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 12	GLU A 218 GLY A 202 LEU A 204 VAL A 365 VAL A 294	None	1.08A	5dpdA-5ci5A: undetectable	5dpdA-5ci5A: 22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESK_A_1YNA701_2 (LANOSTEROL 14-ALPHA DEMETHYLASE)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	4 / 4	ALA A 166 PRO A 155 LEU A 137 HIS A 285	None	1.43A	5eskA-5ci5A: undetectable	5eskA-5ci5A: 21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HI6_A_MTXA201_1 (DIHYDROFOLATE REDUCTASE)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 12	ALA A 366 SER A 377 ILE A 376 LEU A 409 TYR A 198	None	1.06A	5hi6A-5ci5A: undetectable	5hi6A-5ci5A: 16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IAO_C_URFC301_1 (BIFUNCTIONAL PROTEIN PYRR)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	3 / 3	ARG A 367 HIS A 188 ARG A 136	T6T A 501 (-3.0A) None T6T A 501 (-3.0A)	0.87A	5iaoC-5ci5A: undetectable	5iaoC-5ci5A: 17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IAO_F_URFF301_1 (BIFUNCTIONAL PROTEIN PYRR)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	3 / 3	ARG A 367 HIS A 188 ARG A 136	T6T A 501 (-3.0A) None T6T A 501 (-3.0A)	0.90A	5iaoF-5ci5A: undetectable	5iaoF-5ci5A: 17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MM4_B_TA1B501_1 (TUBULIN BETA CHAIN)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 10	VAL A 329 LEU A 295 SER A 346 PHE A 358 THR A 360	None	1.28A	5mm4B-5ci5A: undetectable	5mm4B-5ci5A: 12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N5D_B_SAMB303_0 (METHYLTRANSFERASE)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 12	LEU A 138 ALA A 283 ILE A 276 ALA A 252 PHE A 266	None	1.05A	5n5dB-5ci5A: undetectable	5n5dB-5ci5A: 19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VEU_H_RITH602_1 (CYTOCHROME P450 3A5)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 12	ARG A 367 PHE A 196 GLY A 219 ILE A 260 GLY A 202	T6T A 501 (-3.0A) None None None None	1.06A	5veuH-5ci5A: undetectable	5veuH-5ci5A: 24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YOD_F_BEZF201_0 (NS3 PROTEASE)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	4 / 5	ALA A 230 SER A 236 TYR A 179 TYR A 226	None	1.47A	5yodF-5ci5A: undetectable	5yodF-5ci5A: 16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZW2_A_ACTA511_0 (L-PROLYL-[PEPTIDYL-C ARRIER PROTEIN] DEHYDROGENASE)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	3 / 3	ARG A 248 ILE A 269 SER A 265	None	0.64A	5zw2A-5ci5A: undetectable	5zw2A-5ci5A: 22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZWR_B_9KLB402_0 (EST-Y29)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 12	TYR A 48 PHE A 44 LEU A 22 ALA A 316 LEU A 78	None	1.39A	5zwrB-5ci5A: undetectable	5zwrB-5ci5A: 23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A7J_A_TESA502_0 (CYTOCHROME P450)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	4 / 7	LEU A 162 ALA A 165 ALA A 166 THR A 170	None	0.53A	6a7jA-5ci5A: undetectable	6a7jA-5ci5A: 14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CBZ_B_ESTB602_1 (ESTROGEN RECEPTOR)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	5 / 10	LEU A 223 ALA A 222 LEU A 197 ILE A 260 HIS A 285	None	1.42A	6cbzB-5ci5A: undetectable	6cbzB-5ci5A: 11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FOS_B_PQNB2002_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A2)	5ci5	EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1 (Pseudothermotoga lettingae)	4 / 6	MET A 99 ALA A 79 LEU A 78 ALA A 312	None	0.89A	6fosB-5ci5A: undetectable	6fosB-5ci5A: 11.96

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1AO8_A_MTXA170_2","DIHYDROFOLATE REDUCTASE","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",4,"TRP A 264;LEU A  33;ARG A 339;THR A 338","T6T A 501 (-2.9A);None;None;None","1.33A","1ao8A-5ci5A:0.0","1ao8A-5ci5A:18.46"],["1DDR_A_MTXA200_1","DIHYDROFOLATE REDUCTASE","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"ALA A 366;SER A 377;ILE A 376;LEU A 409;TYR A 198","None","1.02A","1ddrA-5ci5A:undetectable","1ddrA-5ci5A:16.39"],["1DHI_A_MTXA161_1","DIHYDROFOLATE REDUCTASE","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"ALA A 366;SER A 377;ILE A 376;LEU A 409;TYR A 198","None","0.97A","1dhiA-5ci5A:undetectable","1dhiA-5ci5A:16.75"],["1DHJ_A_MTXA161_1","DIHYDROFOLATE REDUCTASE","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"ALA A 366;SER A 377;ILE A 376;LEU A 409;TYR A 198","None","0.97A","1dhjA-5ci5A:undetectable","1dhjA-5ci5A:16.51"],["1DRA_A_MTXA161_1","DIHYDROFOLATE REDUCTASE","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"ALA A 366;SER A 377;ILE A 376;LEU A 409;TYR A 198","None","0.97A","1draA-5ci5A:undetectable","1draA-5ci5A:17.42"],["1DRB_A_MTXA161_1","DIHYDROFOLATE REDUCTASE","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"ALA A 366;SER A 377;ILE A 376;LEU A 409;TYR A 198","None","0.97A","1drbA-5ci5A:undetectable","1drbA-5ci5A:16.75"],["1I9G_A_SAMA301_1","HYPOTHETICAL PROTEIN RV2118C","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",3,"GLU A 244;HIS A 188;ASP A 134","None;None;T6T A 501 (-1.9A)","0.88A","1i9gA-5ci5A:undetectable","1i9gA-5ci5A:21.19"],["1RG7_A_MTXA161_1","DIHYDROFOLATE REDUCTASE","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"ALA A 366;SER A 377;ILE A 376;LEU A 409;TYR A 198","None","0.96A","1rg7A-5ci5A:undetectable","1rg7A-5ci5A:16.39"],["1U18_B_HSMB402_1","NITROPHORIN 1","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",4,"ASP A  82;GLU A 187;THR A 119;LEU A 295","T6T A 501 (-2.3A);None;None;None","1.03A","1u18B-5ci5A:undetectable","1u18B-5ci5A:19.66"],["1U18_B_HSMB402_1","NITROPHORIN 1","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",4,"GLU A 187;THR A 119;LEU A 295;LEU A  83","None","1.04A","1u18B-5ci5A:undetectable","1u18B-5ci5A:19.66"],["1ZZ1_C_SHHC2652_1","HISTONE DEACETYLASE-LIKE AMIDOHYDROLASE","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"LEU A  33;GLY A  28;ASP A 134;GLY A 297;TYR A 132","None;None;T6T A 501 (-1.9A);T6T A 501 (-3.4A);T6T A 501 (-4.4A)","1.09A","1zz1C-5ci5A:undetectable","1zz1C-5ci5A:22.68"],["2DRC_A_MTXA161_1","DIHYDROFOLATE REDUCTASE","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"ALA A 366;SER A 377;ILE A 376;LEU A 409;TYR A 198","None","0.95A","2drcA-5ci5A:undetectable","2drcA-5ci5A:16.99"],["2F80_B_017B301_1","POL POLYPROTEIN;POL POLYPROTEIN","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"ALA A 312;ASP A 311;ASN A 308;PRO A  98;ILE A 302","None","1.00A","2f80A-5ci5A:undetectable","2f80A-5ci5A:12.53"],["2H42_C_VIAC903_2","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",3,"ASN A 151;ILE A 169;MET A 258","None","0.71A","2h42C-5ci5A:undetectable","2h42C-5ci5A:21.51"],["2OIP_D_MTXD617_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"ALA A  81;LEU A  83;THR A 338;ILE A 112;LEU A 103","None","1.15A","2oipD-5ci5A:undetectable","2oipD-5ci5A:20.38"],["2UVN_B_ECNB1406_1","CYTOCHROME P450 130","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"PRO A 371;GLY A  85;LEU A  96;TYR A 127;VAL A 120","None","1.49A","2uvnB-5ci5A:undetectable","2uvnB-5ci5A:21.12"],["3B9L_A_AZZA1009_1","SERUM ALBUMIN","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",4,"GLU A 187;SER A 377;GLN A 381;VAL A 181","None","1.24A","3b9lA-5ci5A:1.8","3b9lA-5ci5A:21.75"],["3DRC_A_MTXA161_1","DIHYDROFOLATE REDUCTASE","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"ALA A 366;SER A 377;ILE A 376;LEU A 409;TYR A 198","None","0.96A","3drcA-5ci5A:undetectable","3drcA-5ci5A:16.39"],["3JZJ_A_ACRA405_1","ACARBOSE\/MALTOSE BINDING PROTEIN GACH","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"ARG A 136;ALA A 366;ASP A  82;TRP A 298;GLY A  84","T6T A 501 (-3.0A);None;T6T A 501 (-2.3A);T6T A 501 (-3.5A);T6T A 501 ( 4.6A)","1.44A","3jzjA-5ci5A:45.6","3jzjA-5ci5A:29.21"],["3JZJ_A_ACRA405_1","ACARBOSE\/MALTOSE BINDING PROTEIN GACH","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"GLY A  58;ASP A 134;ASP A 245;GLY A 296;ARG A 367","None;T6T A 501 (-1.9A);None;T6T A 501 (-3.2A);T6T A 501 (-3.0A)","1.09A","3jzjA-5ci5A:45.6","3jzjA-5ci5A:29.21"],["4DFR_A_MTXA161_1","DIHYDROFOLATE REDUCTASE","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"ALA A 366;SER A 377;ILE A 376;LEU A 409;TYR A 198","None","0.96A","4dfrA-5ci5A:undetectable","4dfrA-5ci5A:16.39"],["4KYK_B_IMNB300_1","LACTOYLGLUTATHIONE LYASE;LACTOYLGLUTATHIONE LYASE","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"PHE A 196;ALA A 200;PHE A 225;LEU A 229;LEU A 138","None","1.25A","4kykA-5ci5A:undetectable;4kykB-5ci5A:undetectable","4kykA-5ci5A:19.76;4kykB-5ci5A:19.76"],["4QI9_A_MTXA201_1","DIHYDROFOLATE REDUCTASE","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"ALA A 366;SER A 377;ILE A 376;LEU A 409;TYR A 198","None","1.02A","4qi9A-5ci5A:undetectable","4qi9A-5ci5A:16.99"],["4QI9_B_MTXB201_1","DIHYDROFOLATE REDUCTASE","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"ALA A 366;SER A 377;ILE A 376;LEU A 409;TYR A 198","None","1.00A","4qi9B-5ci5A:undetectable","4qi9B-5ci5A:16.99"],["4QI9_C_MTXC201_1","DIHYDROFOLATE REDUCTASE","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"ALA A 366;SER A 377;ILE A 376;LEU A 409;TYR A 198","None","1.00A","4qi9C-5ci5A:undetectable","4qi9C-5ci5A:16.99"],["4QLE_B_FOLB201_0","DIHYDROFOLATE REDUCTASE","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"ALA A 366;SER A 377;ILE A 376;LEU A 409;TYR A 198","None","1.01A","4qleB-5ci5A:undetectable","4qleB-5ci5A:18.18"],["5DPD_A_SAMA601_0","PROTEIN LYSINE METHYLTRANSFERASE 1","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"GLU A 218;GLY A 202;LEU A 204;VAL A 365;VAL A 294","None","1.08A","5dpdA-5ci5A:undetectable","5dpdA-5ci5A:22.06"],["5ESK_A_1YNA701_2","LANOSTEROL 14-ALPHA DEMETHYLASE","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",4,"ALA A 166;PRO A 155;LEU A 137;HIS A 285","None","1.43A","5eskA-5ci5A:undetectable","5eskA-5ci5A:21.22"],["5HI6_A_MTXA201_1","DIHYDROFOLATE REDUCTASE","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"ALA A 366;SER A 377;ILE A 376;LEU A 409;TYR A 198","None","1.06A","5hi6A-5ci5A:undetectable","5hi6A-5ci5A:16.30"],["5IAO_C_URFC301_1","BIFUNCTIONAL PROTEIN PYRR","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",3,"ARG A 367;HIS A 188;ARG A 136","T6T A 501 (-3.0A);None;T6T A 501 (-3.0A)","0.87A","5iaoC-5ci5A:undetectable","5iaoC-5ci5A:17.66"],["5IAO_F_URFF301_1","BIFUNCTIONAL PROTEIN PYRR","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",3,"ARG A 367;HIS A 188;ARG A 136","T6T A 501 (-3.0A);None;T6T A 501 (-3.0A)","0.90A","5iaoF-5ci5A:undetectable","5iaoF-5ci5A:17.66"],["5MM4_B_TA1B501_1","TUBULIN BETA CHAIN","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"VAL A 329;LEU A 295;SER A 346;PHE A 358;THR A 360","None","1.28A","5mm4B-5ci5A:undetectable","5mm4B-5ci5A:12.85"],["5N5D_B_SAMB303_0","METHYLTRANSFERASE","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"LEU A 138;ALA A 283;ILE A 276;ALA A 252;PHE A 266","None","1.05A","5n5dB-5ci5A:undetectable","5n5dB-5ci5A:19.04"],["5VEU_H_RITH602_1","CYTOCHROME P450 3A5","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"ARG A 367;PHE A 196;GLY A 219;ILE A 260;GLY A 202","T6T A 501 (-3.0A);None;None;None;None","1.06A","5veuH-5ci5A:undetectable","5veuH-5ci5A:24.13"],["5YOD_F_BEZF201_0","NS3 PROTEASE","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",4,"ALA A 230;SER A 236;TYR A 179;TYR A 226","None","1.47A","5yodF-5ci5A:undetectable","5yodF-5ci5A:16.63"],["5ZW2_A_ACTA511_0","L-PROLYL-[PEPTIDYL-CARRIER PROTEIN] DEHYDROGENASE","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",3,"ARG A 248;ILE A 269;SER A 265","None","0.64A","5zw2A-5ci5A:undetectable","5zw2A-5ci5A:22.32"],["5ZWR_B_9KLB402_0","EST-Y29","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"TYR A  48;PHE A  44;LEU A  22;ALA A 316;LEU A  78","None","1.39A","5zwrB-5ci5A:undetectable","5zwrB-5ci5A:23.39"],["6A7J_A_TESA502_0","CYTOCHROME P450","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",4,"LEU A 162;ALA A 165;ALA A 166;THR A 170","None","0.53A","6a7jA-5ci5A:undetectable","6a7jA-5ci5A:14.72"],["6CBZ_B_ESTB602_1","ESTROGEN RECEPTOR","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",5,"LEU A 223;ALA A 222;LEU A 197;ILE A 260;HIS A 285","None","1.42A","6cbzB-5ci5A:undetectable","6cbzB-5ci5A:11.85"],["6FOS_B_PQNB2002_1","PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A2","5ci5","EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1","Pseudothermotoga lettingae",4,"MET A  99;ALA A  79;LEU A  78;ALA A 312","None","0.89A","6fosB-5ci5A:undetectable","6fosB-5ci5A:11.96"]]