SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cj0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_1
(PROTEASE)		 5cj0 XRCC4-MYH7-(1631-169
2) CHIMERA PROTEIN
(Homo
sapiens) 		5 / 12 LEU A 126
ALA A  42
GLY A  45
ILE A  34
VAL A 122
 None
 0.77A 3gguA-5cj0A:
undetectable		 3gguA-5cj0A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)		 5cj0 XRCC4-MYH7-(1631-169
2) CHIMERA PROTEIN
(Homo
sapiens) 		5 / 9 LEU A 126
ALA A  42
GLY A  45
ILE A  34
VAL A 122
 None
 0.77A 3u7sA-5cj0A:
undetectable		 3u7sA-5cj0A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_A_DM2A1106_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5cj0 XRCC4-MYH7-(1631-169
2) CHIMERA PROTEIN
(Homo
sapiens) 		5 / 11 PHE A 111
PHE A  96
PHE A  97
LEU A  70
ALA A  78
 None
 1.38A 4dx7A-5cj0A:
undetectable		 4dx7A-5cj0A:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 5cj0 XRCC4-MYH7-(1631-169
2) CHIMERA PROTEIN
(Homo
sapiens) 		4 / 7 SER A  53
ALA A  56
GLY A  64
VAL A  67
 None
 0.72A 5fpdA-5cj0A:
undetectable		 5fpdA-5cj0A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5cj0 XRCC4-MYH7-(1631-169
2) CHIMERA PROTEIN
(Homo
sapiens) 		5 / 12 LEU A  28
ILE A  34
LEU A 108
ALA A  73
TYR A  66
 None
 1.11A 6djzA-5cj0A:
undetectable		 6djzA-5cj0A:
21.40