SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cj3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)
5cj3 ZBM BINDING PROTEIN
(Streptomyces
flavoviridis)
3 / 3 TRP A  78
ALA A  80
VAL A  82
None
0.87A 1bdwA-5cj3A:
undetectable
1bdwB-5cj3A:
undetectable
1bdwA-5cj3A:
12.20
1bdwB-5cj3A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)
5cj3 ZBM BINDING PROTEIN
(Streptomyces
flavoviridis)
4 / 5 PHE A  29
LEU A 108
VAL A 116
VAL A  68
None
1.11A 1t88B-5cj3A:
undetectable
1t88B-5cj3A:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)
5cj3 ZBM BINDING PROTEIN
(Streptomyces
flavoviridis)
4 / 6 PHE A  29
LEU A 108
VAL A 116
VAL A  68
None
1.06A 2feuA-5cj3A:
undetectable
2feuA-5cj3A:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)
5cj3 ZBM BINDING PROTEIN
(Streptomyces
flavoviridis)
4 / 6 PHE A  29
LEU A 108
VAL A 116
VAL A  68
None
1.17A 2zawA-5cj3A:
undetectable
2zawA-5cj3A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)
5cj3 ZBM BINDING PROTEIN
(Streptomyces
flavoviridis)
4 / 7 ALA A  13
ASN A 114
PRO A 111
ALA A 112
None
1.14A 2zgwA-5cj3A:
undetectable
2zgwA-5cj3A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)
5cj3 ZBM BINDING PROTEIN
(Streptomyces
flavoviridis)
4 / 6 ALA A  13
ASN A 114
PRO A 111
ALA A 112
None
1.18A 2zgwB-5cj3A:
undetectable
2zgwB-5cj3A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
5cj3 ZBM BINDING PROTEIN
(Streptomyces
flavoviridis)
4 / 6 PHE A  29
LEU A 108
VAL A 116
VAL A  68
None
1.08A 3fwgA-5cj3A:
undetectable
3fwgA-5cj3A:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)
5cj3 ZBM BINDING PROTEIN
(Streptomyces
flavoviridis)
4 / 6 PHE A  29
LEU A 108
VAL A 116
VAL A  68
None
1.06A 3wrjE-5cj3A:
undetectable
3wrjE-5cj3A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
5cj3 ZBM BINDING PROTEIN
(Streptomyces
flavoviridis)
4 / 6 PHE A  29
LEU A 108
VAL A 116
VAL A  68
None
1.03A 4ek1A-5cj3A:
undetectable
4ek1A-5cj3A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)
5cj3 ZBM BINDING PROTEIN
(Streptomyces
flavoviridis)
4 / 6 PHE A  29
LEU A 108
VAL A 116
VAL A  68
None
1.12A 4kkyX-5cj3A:
undetectable
4kkyX-5cj3A:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
5cj3 ZBM BINDING PROTEIN
(Streptomyces
flavoviridis)
4 / 5 PHE A  29
LEU A 108
VAL A 116
VAL A  68
None
1.08A 4l49A-5cj3A:
undetectable
4l49A-5cj3A:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)
5cj3 ZBM BINDING PROTEIN
(Streptomyces
flavoviridis)
3 / 3 GLU A 105
ARG A  98
GLN A  63
52G  A 201 ( 4.9A)
52G  A 201 (-3.8A)
52G  A 201 ( 3.9A)
0.96A 4rtbA-5cj3A:
undetectable
4rtbA-5cj3A:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_1
(RIBOFLAVIN LYASE)
5cj3 ZBM BINDING PROTEIN
(Streptomyces
flavoviridis)
6 / 12 PHE A  22
GLY A 113
ALA A 112
PHE A 118
VAL A 116
THR A  19
None
52G  A 201 (-3.7A)
None
None
None
None
1.35A 5w4zA-5cj3A:
undetectable
5w4zA-5cj3A:
20.14