SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cj5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 5 THR A 107
GLU A 589
THR A 592
LEU A 690
None
1.15A 1d4fC-5cj5A:
undetectable
1d4fC-5cj5A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLF_A_NVPA999_1
(HIV-1 RT A-CHAIN
HIV-1 RT B-CHAIN)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 8 LEU A  59
VAL A  14
GLY A  17
TRP A 218
None
1.01A 1jlfA-5cj5A:
undetectable
1jlfB-5cj5A:
3.3
1jlfA-5cj5A:
21.15
1jlfB-5cj5A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 5 VAL A 412
SER A 441
ASP A 498
GLN A 343
None
1.27A 1n2xB-5cj5A:
undetectable
1n2xB-5cj5A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 5 LEU A 587
ASP A 615
ALA A 586
ILE A 580
None
1.08A 2qhfA-5cj5A:
undetectable
2qhfA-5cj5A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 7 THR A 107
PRO A 108
VAL A  25
GLU A 589
None
0.95A 2v2gA-5cj5A:
undetectable
2v2gB-5cj5A:
undetectable
2v2gA-5cj5A:
16.69
2v2gB-5cj5A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 7 THR A 107
PRO A 108
VAL A  25
GLU A 589
None
0.95A 2v2gA-5cj5A:
undetectable
2v2gB-5cj5A:
undetectable
2v2gA-5cj5A:
16.69
2v2gB-5cj5A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 7 THR A 107
PRO A 108
VAL A  25
GLU A 589
None
0.93A 2v2gC-5cj5A:
undetectable
2v2gD-5cj5A:
undetectable
2v2gC-5cj5A:
16.69
2v2gD-5cj5A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 7 THR A 107
PRO A 108
VAL A  25
GLU A 589
None
0.93A 2v2gC-5cj5A:
undetectable
2v2gD-5cj5A:
undetectable
2v2gC-5cj5A:
16.69
2v2gD-5cj5A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 8 THR A 107
PRO A 108
VAL A  25
GLU A 589
None
0.95A 2v32A-5cj5A:
undetectable
2v32B-5cj5A:
undetectable
2v32A-5cj5A:
16.69
2v32B-5cj5A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 8 THR A 107
PRO A 108
VAL A  25
GLU A 589
None
0.97A 2v32A-5cj5A:
undetectable
2v32B-5cj5A:
undetectable
2v32A-5cj5A:
16.69
2v32B-5cj5A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 8 THR A 107
PRO A 108
VAL A  25
GLU A 589
None
0.92A 2v32C-5cj5A:
undetectable
2v32D-5cj5A:
undetectable
2v32C-5cj5A:
16.69
2v32D-5cj5A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 8 THR A 107
PRO A 108
VAL A  25
GLU A 589
None
0.98A 2v32C-5cj5A:
undetectable
2v32D-5cj5A:
undetectable
2v32C-5cj5A:
16.69
2v32D-5cj5A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 8 THR A 107
PRO A 108
VAL A  25
GLU A 589
None
0.98A 2v41C-5cj5A:
undetectable
2v41D-5cj5A:
undetectable
2v41C-5cj5A:
16.69
2v41D-5cj5A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 8 THR A 107
PRO A 108
VAL A  25
GLU A 589
None
0.90A 2v41C-5cj5A:
undetectable
2v41D-5cj5A:
undetectable
2v41C-5cj5A:
16.69
2v41D-5cj5A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 7 THR A 107
PRO A 108
VAL A  25
GLU A 589
None
1.05A 2v41E-5cj5A:
undetectable
2v41F-5cj5A:
undetectable
2v41E-5cj5A:
16.69
2v41F-5cj5A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 7 THR A 107
PRO A 108
VAL A  25
GLU A 589
None
1.01A 2v41E-5cj5A:
undetectable
2v41F-5cj5A:
undetectable
2v41E-5cj5A:
16.69
2v41F-5cj5A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 8 THR A 107
PRO A 108
VAL A  25
GLU A 589
None
0.91A 2v41G-5cj5A:
undetectable
2v41H-5cj5A:
undetectable
2v41G-5cj5A:
16.69
2v41H-5cj5A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 8 THR A 107
PRO A 108
VAL A  25
GLU A 589
None
0.93A 2v41G-5cj5A:
undetectable
2v41H-5cj5A:
undetectable
2v41G-5cj5A:
16.69
2v41H-5cj5A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 7 THR A 107
PRO A 108
GLY A  26
LEU A 693
None
1.02A 2vl2B-5cj5A:
undetectable
2vl2B-5cj5A:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_2
(CYTOCHROME P450 2R1)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
3 / 3 MET A 681
VAL A 620
GLU A 653
None
0.89A 3c6gA-5cj5A:
undetectable
3c6gA-5cj5A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_J_ACHJ323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 8 GLU A 356
LEU A 382
PHE A 358
PHE A 384
None
1.10A 3rqwF-5cj5A:
undetectable
3rqwJ-5cj5A:
undetectable
3rqwF-5cj5A:
17.86
3rqwJ-5cj5A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 4 LEU A 178
GLY A 152
LEU A 156
GLU A 157
None
1.08A 3tgvB-5cj5A:
undetectable
3tgvB-5cj5A:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
3 / 3 LYS A 431
ARG A 489
LEU A 438
None
1.10A 3v4tE-5cj5A:
undetectable
3v4tE-5cj5A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
5 / 12 PHE A 322
LEU A 271
VAL A 269
ALA A 327
SER A 328
None
1.23A 4a84A-5cj5A:
undetectable
4a84A-5cj5A:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMU_C_RFPC1401_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
5 / 12 ASP A 378
HIS A 281
SER A 365
LEU A 361
ILE A 366
None
1.28A 4kmuC-5cj5A:
undetectable
4kmuC-5cj5A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_A_ACTA603_0
(CHOLINE OXIDASE)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
3 / 3 ARG A 235
HIS A 248
SER A 236
None
1.01A 4mjwA-5cj5A:
undetectable
4mjwB-5cj5A:
undetectable
4mjwA-5cj5A:
22.63
4mjwB-5cj5A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
3 / 3 SER A 236
ARG A 235
HIS A 248
None
1.03A 4mjwA-5cj5A:
undetectable
4mjwB-5cj5A:
undetectable
4mjwA-5cj5A:
22.63
4mjwB-5cj5A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_H_377H401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 6 ASN A 578
GLU A 571
GLU A 533
TYR A 230
None
1.03A 4twdG-5cj5A:
0.9
4twdH-5cj5A:
undetectable
4twdG-5cj5A:
17.08
4twdH-5cj5A:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGL_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
3 / 3 ARG A  37
THR A  34
TRP A  36
None
1.25A 4uglA-5cj5A:
0.2
4uglA-5cj5A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
5 / 12 THR A 253
LEU A 258
ARG A 558
HIS A 313
LEU A 316
None
1.31A 4xi3D-5cj5A:
undetectable
4xi3D-5cj5A:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
3 / 3 TRP A 350
GLU A 394
ASP A 310
None
1.03A 5gqbA-5cj5A:
11.4
5gqbA-5cj5A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
3 / 3 GLY A  53
LEU A 113
HIS A  52
None
0.66A 5u63A-5cj5A:
undetectable
5u63A-5cj5A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
3 / 3 GLY A  53
LEU A 113
HIS A  52
None
0.67A 5u63B-5cj5A:
undetectable
5u63B-5cj5A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 7 HIS A 416
ASN A 414
GLU A 442
ARG A 411
None
1.04A 6b8kA-5cj5A:
undetectable
6b8kA-5cj5A:
8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 4 ASP A 615
ILE A 684
PRO A 685
LEU A 683
None
1.47A 6mkeB-5cj5A:
undetectable
6mkeB-5cj5A:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacteriu
m
thermoresistibil
e)
4 / 4 ASP A 615
ILE A 684
PRO A 685
LEU A 683
None
1.41A 6mkeA-5cj5A:
undetectable
6mkeA-5cj5A:
9.34