SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cjj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_1
(TRANSTHYRETIN)		 5cjj PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Campylobacter
jejuni) 		4 / 7 ALA A   6
LEU A  39
SER A  10
THR A  88
 None
None
None
GOL  A 201 (-3.7A)
 0.71A 1dvxA-5cjjA:
undetectable		 1dvxA-5cjjA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)		 5cjj PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 THR A  58
GLY A  11
GLY A  13
ILE A  48
ALA A  91
 None
 0.85A 1nv8B-5cjjA:
3.8		 1nv8B-5cjjA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5cjj PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Campylobacter
jejuni) 		4 / 6 ASP A  73
LEU A  76
VAL A  77
ILE A  80
 None
None
None
GOL  A 201 (-4.6A)
 0.37A 1s9qA-5cjjA:
undetectable		 1s9qA-5cjjA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_0
(HEMK PROTEIN)		 5cjj PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 THR A  58
GLY A  11
GLY A  13
ILE A  48
ALA A  91
 None
 0.90A 1sg9B-5cjjA:
3.8		 1sg9B-5cjjA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_B_SAMB301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 5cjj PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 THR A  58
GLY A  11
GLY A  13
ILE A  48
ALA A  91
 None
 0.89A 1vq1B-5cjjA:
3.8		 1vq1B-5cjjA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 5cjj PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 ILE A 108
VAL A  89
LEU A   5
VAL A   7
LEU A  23
 None
 0.84A 2aw1A-5cjjA:
undetectable		 2aw1A-5cjjA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 5cjj PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 ILE A  96
LEU A  97
ASN A 109
PRO A 112
VAL A 142
 None
None
CL  A 203 (-3.9A)
None
None
 0.84A 3dcjA-5cjjA:
23.8
3dcjB-5cjjA:
23.6		 3dcjA-5cjjA:
26.70
3dcjB-5cjjA:
26.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 5cjj PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 PRO A  99
VAL A 142
HIS A 140
 None
 0.74A 4pevC-5cjjA:
5.2		 4pevC-5cjjA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 5cjj PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Campylobacter
jejuni) 		4 / 7 LEU A 181
GLU A 185
SER A 182
ILE A 178
 None
 1.18A 4tvtA-5cjjA:
undetectable		 4tvtA-5cjjA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 5cjj PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 GLU A  17
ALA A  51
PHE A  54
 None
 0.49A 4v1fA-5cjjA:
undetectable		 4v1fA-5cjjA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 5cjj PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 GLU A  17
ALA A  51
PHE A  54
 None
 0.50A 4v1fC-5cjjA:
undetectable		 4v1fC-5cjjA:
19.89