SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cjs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 5cjs DESIGNED INFLUENZA
HEMAGGLUTININ STEM
#4454, HA2
(synthetic
construct) 		5 / 12 SER D 166
TYR D 162
TYR D 159
TYR D 157
ASN D 128
 None
 1.45A 3bjmA-5cjsD:
undetectable		 3bjmA-5cjsD:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 5cjs DESIGNED INFLUENZA
HEMAGGLUTININ STEM
#4454, HA2
(synthetic
construct) 		5 / 12 SER D 166
TYR D 162
TYR D 159
TYR D 157
ASN D 128
 None
 1.47A 3w2tA-5cjsD:
undetectable		 3w2tA-5cjsD:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 5cjs DESIGNED INFLUENZA
HEMAGGLUTININ STEM
#4454, HA2
(synthetic
construct) 		5 / 12 SER D 166
TYR D 162
TYR D 159
TYR D 157
ASN D 128
 None
 1.46A 3w2tB-5cjsD:
undetectable		 3w2tB-5cjsD:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		 5cjs DESIGNED INFLUENZA
HEMAGGLUTININ STEM
#4454, HA2
(synthetic
construct) 		4 / 8 ASN D  28
GLN D  27
GLY D  31
SER D  32
 None
 0.96A 4f93B-5cjsD:
undetectable		 4f93B-5cjsD:
9.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 5cjs DESIGNED INFLUENZA
HEMAGGLUTININ STEM
#4454, HA1
DESIGNED INFLUENZA
HEMAGGLUTININ STEM
#4454, HA2
(synthetic
construct) 		4 / 4 VAL D  55
ILE D  48
ASN D 104
VAL C  40
 None
 1.17A 5ajqA-5cjsD:
undetectable		 5ajqA-5cjsD:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5INZ_D_DVAD15_0
(THETA DEFENSIN-2,
D-PEPTIDE
THETA DEFENSIN-2,
L-PEPTIDE)		 5cjs DESIGNED INFLUENZA
HEMAGGLUTININ STEM
#4454, HA1
DESIGNED INFLUENZA
HEMAGGLUTININ STEM
#4454, HA2
(synthetic
construct;
synthetic
construct) 		3 / 3 GLY D   8
CYH D 137
CYH C  14
 None
 0.80A 5inzB-5cjsD:
undetectable		 5inzB-5cjsD:
4.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 5cjs DESIGNED INFLUENZA
HEMAGGLUTININ STEM
#4454, HA2
(synthetic
construct) 		5 / 12 SER D 166
TYR D 162
TYR D 159
TYR D 157
ASN D 128
 None
 1.47A 6b1eB-5cjsD:
undetectable		 6b1eB-5cjsD:
13.31