SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ck0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 225
ARG A 156
ILE A 190
 None
 0.73A 1uobA-5ck0A:
undetectable		 1uobA-5ck0A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 7 PHE A 381
PHE A 561
PHE A 384
MET A 431
 None
 1.15A 1wrlE-5ck0A:
undetectable		 1wrlE-5ck0A:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		3 / 3 TRP A 577
GLU A 579
TYR A 583
 None
 1.01A 2a3aA-5ck0A:
undetectable		 2a3aA-5ck0A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 6 GLU A 590
ASP A  75
PHE A 584
ARG A 570
 None
 1.27A 2a3bB-5ck0A:
undetectable		 2a3bB-5ck0A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 408
VAL A 307
PHE A 433
GLY A 409
ILE A 410
 None
 1.38A 2dcfA-5ck0A:
undetectable		 2dcfA-5ck0A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 6 ILE A 416
ARG A 413
PRO A 356
SER A 372
 None
 1.24A 2qd3B-5ck0A:
undetectable		 2qd3B-5ck0A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_A_LDPA501_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 7 GLU A 336
GLY A 495
PHE A 351
PHE A 349
 None
 1.03A 2qmzA-5ck0A:
undetectable
2qmzB-5ck0A:
undetectable		 2qmzA-5ck0A:
15.13
2qmzB-5ck0A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_GLYA333_0
(CHOLOYLGLYCINE
HYDROLASE)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		3 / 3 ASN A  71
ASN A 566
ARG A 354
 None
 0.81A 2rlcA-5ck0A:
undetectable		 2rlcA-5ck0A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_B_CL9B401_1
(DEOXYCYTIDINE KINASE)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 218
VAL A  58
LEU A 345
ARG A 156
PHE A 503
 None
 1.25A 2ziaB-5ck0A:
undetectable		 2ziaB-5ck0A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GM0_A_B41A600_1
(ANTI-METHAMPHETAMINE
SINGLE CHAIN FV)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		5 / 11 TYR A 352
SER A 353
TYR A  66
TYR A 371
PHE A 351
 None
 1.47A 3gm0A-5ck0A:
undetectable		 3gm0A-5ck0A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 7 GLU A 524
GLN A 276
VAL A 512
ALA A 528
 None
 0.94A 3kp6B-5ck0A:
0.2		 3kp6B-5ck0A:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		5 / 12 THR A 215
GLY A 286
ALA A 282
ALA A 278
LEU A 508
 None
 1.07A 3p5nA-5ck0A:
1.4		 3p5nA-5ck0A:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		5 / 12 THR A 215
GLY A 286
ALA A 282
ALA A 278
LEU A 508
 None
 1.08A 3p5nB-5ck0A:
1.4		 3p5nB-5ck0A:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 5 VAL A 187
ILE A 163
MET A 636
ARG A 225
 None
 1.43A 3pyyB-5ck0A:
undetectable		 3pyyB-5ck0A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 8 TYR A 642
TYR A 241
TRP A 616
LEU A 234
 None
 1.18A 3uzzB-5ck0A:
undetectable		 3uzzB-5ck0A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_B_IMNB201_1
(TRANSTHYRETIN)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 6 LEU A 529
ALA A 525
LEU A 541
THR A 522
 None
 0.97A 4ikiB-5ck0A:
undetectable		 4ikiB-5ck0A:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 8 ARG A 157
PHE A 571
GLY A  90
THR A  73
 None
 1.01A 4k87A-5ck0A:
undetectable		 4k87A-5ck0A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		5 / 12 TRP A 343
GLY A 212
ARG A 213
LEU A 201
PRO A 202
 None
 1.36A 4uinH-5ck0A:
undetectable
4uinL-5ck0A:
undetectable		 4uinH-5ck0A:
17.83
4uinL-5ck0A:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_C_URFC301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 156
HIS A 569
ARG A 225
 None
 1.12A 5iaoC-5ck0A:
undetectable		 5iaoC-5ck0A:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_F_URFF301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 156
HIS A 569
ARG A 225
 None
 1.13A 5iaoF-5ck0A:
undetectable		 5iaoF-5ck0A:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 6 PHE A 249
TYR A 185
ILE A 163
ASP A 165
 None
 1.27A 5iwuA-5ck0A:
undetectable		 5iwuA-5ck0A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 166
TYR A 167
TYR A 117
 None
 0.62A 5lakA-5ck0A:
undetectable
5lakI-5ck0A:
undetectable		 5lakA-5ck0A:
19.54
5lakI-5ck0A:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 166
TYR A 167
TYR A 117
 None
 0.67A 5lakC-5ck0A:
undetectable
5lakJ-5ck0A:
undetectable		 5lakC-5ck0A:
19.54
5lakJ-5ck0A:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 470
SER A 372
PHE A 604
 None
 0.94A 5mugA-5ck0A:
undetectable		 5mugA-5ck0A:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 389
GLY A 537
LEU A 391
ASN A 558
PHE A 398
 None
None
None
None
K  A 702 ( 4.0A)
 1.36A 5yn6A-5ck0A:
undetectable		 5yn6A-5ck0A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 413
ILE A 410
SER A 412
 None
 0.85A 5zw2A-5ck0A:
undetectable		 5zw2A-5ck0A:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 5ck0 SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		5 / 12 HIS A 151
PHE A 572
LEU A 105
THR A 108
THR A 109
 None
 1.20A 6bbsA-5ck0A:
undetectable		 6bbsA-5ck0A:
8.60