SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ck7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_CCSA381_0
(ESTROGEN RECEPTOR)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		4 / 5 HIS A 295
GLU A 297
ALA A 481
HIS A 386
 None
None
None
AMP  A 601 (-4.8A)
 1.43A 1errA-5ck7A:
undetectable
1errB-5ck7A:
undetectable		 1errA-5ck7A:
20.94
1errB-5ck7A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		5 / 11 ALA A  95
LEU A  96
LEU A  92
LEU A 210
ALA A 143
 None
 1.05A 1h9zA-5ck7A:
undetectable		 1h9zA-5ck7A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		5 / 11 ALA A  95
LEU A  96
LEU A  92
LEU A 210
ALA A 143
 None
 1.04A 1ha2A-5ck7A:
undetectable		 1ha2A-5ck7A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		4 / 4 LEU A 260
LEU A 321
SER A 320
LEU A 487
 None
 1.16A 1ya3A-5ck7A:
undetectable		 1ya3A-5ck7A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		4 / 5 SER A  55
SER A  52
THR A 421
ASN A 422
 None
 1.30A 1yvpA-5ck7A:
4.1		 1yvpA-5ck7A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1294_1
(FICOLIN-2)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		5 / 9 GLY A 352
SER A 355
LEU A 358
LEU A 328
ASP A 350
 None
 1.34A 2j2pB-5ck7A:
undetectable
2j2pC-5ck7A:
undetectable		 2j2pB-5ck7A:
17.41
2j2pC-5ck7A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		5 / 12 ASP A  84
GLY A 157
GLY A 158
GLY A 477
ASP A 480
 None
None
None
None
AMP  A 601 ( 4.9A)
 0.72A 2pkkA-5ck7A:
14.2		 2pkkA-5ck7A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		5 / 12 ASP A  84
GLY A 157
GLY A 158
GLY A 477
ASP A 480
 None
None
None
None
AMP  A 601 ( 4.9A)
 0.74A 2pkmA-5ck7A:
16.4		 2pkmA-5ck7A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		5 / 12 ILE A 163
ALA A 160
GLY A 158
VAL A 476
GLY A 477
 None
 1.09A 2qe6B-5ck7A:
4.1		 2qe6B-5ck7A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		4 / 7 LEU A 115
ALA A 118
PHE A 122
PHE A 229
 None
 0.95A 2vcvL-5ck7A:
undetectable		 2vcvL-5ck7A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		3 / 3 HIS A 379
HIS A 386
HIS A 381
 None
AMP  A 601 (-4.8A)
AMP  A 601 (-4.2A)
 0.82A 3mihA-5ck7A:
undetectable		 3mihA-5ck7A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		3 / 3 HIS A 381
HIS A 379
HIS A 386
 AMP  A 601 (-4.2A)
None
AMP  A 601 (-4.8A)
 0.79A 3mihA-5ck7A:
undetectable		 3mihA-5ck7A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		3 / 3 HIS A 386
HIS A 381
HIS A 379
 AMP  A 601 (-4.8A)
AMP  A 601 (-4.2A)
None
 0.82A 3mihA-5ck7A:
undetectable		 3mihA-5ck7A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		5 / 12 ASP A  84
GLY A 157
GLY A 158
GLY A 477
ASP A 480
 None
None
None
None
AMP  A 601 ( 4.9A)
 0.63A 3uboA-5ck7A:
19.4		 3uboA-5ck7A:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		5 / 12 VAL A 193
LEU A 173
ILE A 163
PHE A 488
VAL A 408
 None
 1.11A 3w67C-5ck7A:
1.4		 3w67C-5ck7A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		5 / 12 VAL A 193
LEU A 173
ILE A 163
PHE A 488
VAL A 408
 None
 1.16A 3w68A-5ck7A:
undetectable		 3w68A-5ck7A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		5 / 12 ASP A  84
GLY A 157
GLY A 158
GLY A 477
ASP A 480
 None
None
None
None
AMP  A 601 ( 4.9A)
 0.76A 4dc3B-5ck7A:
20.2		 4dc3B-5ck7A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_A_ADNA401_1
(APH(2'')-ID)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		5 / 10 ILE A 357
ILE A 378
HIS A 365
LEU A 321
ILE A 361
 None
 1.13A 4dtaA-5ck7A:
undetectable		 4dtaA-5ck7A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ENH_A_FVXA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		5 / 12 PHE A 231
LEU A  96
ILE A 142
ALA A 143
ALA A 152
 None
 0.87A 4enhA-5ck7A:
undetectable		 4enhA-5ck7A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_B_9TPB601_1
(SERUM ALBUMIN)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		5 / 12 LEU A 257
ALA A 284
ILE A 163
LEU A 176
LEU A 177
 None
 1.22A 4l9qB-5ck7A:
undetectable		 4l9qB-5ck7A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		4 / 8 LEU A 243
MET A 301
LEU A 296
HIS A 295
 None
 0.87A 4ok1A-5ck7A:
undetectable		 4ok1A-5ck7A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		3 / 3 SER A 490
GLU A 297
GLU A 325
 None
 0.80A 4ymgB-5ck7A:
4.7		 4ymgB-5ck7A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		4 / 5 GLN A 254
PRO A 255
ILE A 292
ASP A 256
 None
 1.36A 4z4hA-5ck7A:
undetectable		 4z4hA-5ck7A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		4 / 5 SER A 320
ALA A 319
HIS A 295
LEU A 257
 None
 1.49A 5dzkb-5ck7A:
1.7
5dzkp-5ck7A:
undetectable		 5dzkb-5ck7A:
20.42
5dzkp-5ck7A:
3.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		4 / 5 SER A 320
ALA A 319
HIS A 295
LEU A 257
 None
 1.37A 5dzkf-5ck7A:
undetectable
5dzkt-5ck7A:
undetectable		 5dzkf-5ck7A:
20.42
5dzkt-5ck7A:
3.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HA9_B_TP0B406_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		5 / 9 GLU A 327
ASP A 480
HIS A 295
ASN A 159
ILE A 163
 None
AMP  A 601 ( 4.9A)
None
None
None
 1.47A 5ha9B-5ck7A:
undetectable		 5ha9B-5ck7A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HA9_B_TP0B406_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		5 / 9 GLU A 327
ASP A 480
SER A 261
ASN A 159
ILE A 163
 None
AMP  A 601 ( 4.9A)
None
None
None
 1.43A 5ha9B-5ck7A:
undetectable		 5ha9B-5ck7A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		5 / 12 GLU A 297
VAL A 175
LEU A 173
SER A 483
ILE A 163
 None
 1.19A 5vooA-5ck7A:
3.2		 5vooA-5ck7A:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		5 / 12 GLU A 297
VAL A 175
LEU A 173
SER A 483
ILE A 163
 None
 1.15A 5vooC-5ck7A:
3.3		 5vooC-5ck7A:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_1
(CYTOCHROME P450 1A1)		 5ck7 ADP-DEPENDENT
GLUCOKINASE
(Mus
musculus) 		4 / 7 SER A 320
GLY A 486
ALA A 401
VAL A 451
 None
 0.78A 6dwnB-5ck7A:
undetectable		 6dwnB-5ck7A:
9.98