SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ckq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5ckq MANNAN-BINDING
LECTIN SERINE
PROTEASE 1
(Rattus
norvegicus) 		4 / 7 PRO A 246
ILE A 249
PRO A 239
GLY A 238
 None
 0.95A 2y7kA-5ckqA:
undetectable		 2y7kA-5ckqA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 5ckq MANNAN-BINDING
LECTIN SERINE
PROTEASE 1
(Rattus
norvegicus) 		3 / 3 ASP A 263
GLY A 266
TYR A 225
 CA  A 303 (-3.7A)
CA  A 303 (-3.5A)
None
 0.74A 3w9tC-5ckqA:
undetectable		 3w9tC-5ckqA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 5ckq MANNAN-BINDING
LECTIN SERINE
PROTEASE 1
(Rattus
norvegicus) 		3 / 3 ASP A 263
GLY A 266
TYR A 225
 CA  A 303 (-3.7A)
CA  A 303 (-3.5A)
None
 0.74A 3w9tG-5ckqA:
undetectable		 3w9tG-5ckqA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)		 5ckq MANNAN-BINDING
LECTIN SERINE
PROTEASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  46
PHE A  43
ALA A  69
LEU A  41
 None
 0.73A 4ejgC-5ckqA:
undetectable		 4ejgC-5ckqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)		 5ckq MANNAN-BINDING
LECTIN SERINE
PROTEASE 1
(Rattus
norvegicus) 		4 / 7 PHE A 112
PHE A  46
PHE A  43
LEU A  41
 None
 0.82A 4ejgC-5ckqA:
undetectable		 4ejgC-5ckqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5ckq MANNAN-BINDING
LECTIN SERINE
PROTEASE 1
(Rattus
norvegicus) 		4 / 4 LEU A  48
GLY A  73
SER A  50
SER A  51
 None
 1.09A 5uunA-5ckqA:
undetectable		 5uunA-5ckqA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5ckq MANNAN-BINDING
LECTIN SERINE
PROTEASE 1
(Rattus
norvegicus) 		4 / 4 LEU A  48
GLY A  73
SER A  50
SER A  51
 None
 1.15A 5uunB-5ckqA:
undetectable		 5uunB-5ckqA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA307_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 5ckq MANNAN-BINDING
LECTIN SERINE
PROTEASE 1
(Rattus
norvegicus) 		4 / 5 ASP A  57
PRO A  83
GLU A  75
ARG A  74
 CA  A 305 (-2.7A)
None
None
None
 1.04A 5uxcA-5ckqA:
undetectable		 5uxcA-5ckqA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA307_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 5ckq MANNAN-BINDING
LECTIN SERINE
PROTEASE 1
(Rattus
norvegicus) 		4 / 5 PRO A  83
GLU A  75
ARG A  74
THR A  82
 None
 1.09A 5uxcA-5ckqA:
undetectable		 5uxcA-5ckqA:
18.07