SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cl2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 5cl2 SPORULATION-CONTROL
PROTEIN SPO0M
(Bacillus
subtilis) 		5 / 12 ARG A 167
PHE A 171
ALA A 162
PHE A 165
LEU A 196
 None
 1.21A 1og5B-5cl2A:
undetectable		 1og5B-5cl2A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 5cl2 SPORULATION-CONTROL
PROTEIN SPO0M
(Bacillus
subtilis) 		4 / 7 PHE A 206
LEU A 202
ILE A 252
VAL A 248
 None
 0.80A 1p2yA-5cl2A:
undetectable		 1p2yA-5cl2A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 5cl2 SPORULATION-CONTROL
PROTEIN SPO0M
(Bacillus
subtilis) 		3 / 3 THR A  98
GLU A 199
HIS A 137
 None
 0.88A 1xwfA-5cl2A:
undetectable		 1xwfA-5cl2A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)		 5cl2 SPORULATION-CONTROL
PROTEIN SPO0M
(Bacillus
subtilis) 		3 / 3 THR A  98
GLU A 199
HIS A 137
 None
 0.83A 1xwfB-5cl2A:
undetectable		 1xwfB-5cl2A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 5cl2 SPORULATION-CONTROL
PROTEIN SPO0M
(Bacillus
subtilis) 		3 / 3 THR A  98
GLU A 199
HIS A 137
 None
 0.83A 1xwfC-5cl2A:
undetectable		 1xwfC-5cl2A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 5cl2 SPORULATION-CONTROL
PROTEIN SPO0M
(Bacillus
subtilis) 		3 / 3 THR A  98
GLU A 199
HIS A 137
 None
 0.80A 1xwfD-5cl2A:
undetectable		 1xwfD-5cl2A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 5cl2 SPORULATION-CONTROL
PROTEIN SPO0M
(Bacillus
subtilis) 		3 / 3 PHE A 195
PHE A 175
PHE A 177
 None
 0.66A 2od9A-5cl2A:
undetectable		 2od9A-5cl2A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEO_A_LNRA200_1
(D7R4 PROTEIN)		 5cl2 SPORULATION-CONTROL
PROTEIN SPO0M
(Bacillus
subtilis) 		5 / 12 GLU A 174
ARG A 210
VAL A 172
PHE A 165
MET A 222
 None
 1.49A 2qeoA-5cl2A:
undetectable		 2qeoA-5cl2A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 5cl2 SPORULATION-CONTROL
PROTEIN SPO0M
(Bacillus
subtilis) 		3 / 3 PHE A 195
PHE A 175
PHE A 177
 None
 0.66A 2qqgA-5cl2A:
undetectable		 2qqgA-5cl2A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)		 5cl2 SPORULATION-CONTROL
PROTEIN SPO0M
(Bacillus
subtilis) 		5 / 12 ILE A  74
ILE A 132
ALA A 113
VAL A 110
PRO A 104
 None
 1.14A 3a51E-5cl2A:
undetectable		 3a51E-5cl2A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 5cl2 SPORULATION-CONTROL
PROTEIN SPO0M
(Bacillus
subtilis) 		4 / 8 VAL A 172
LEU A 219
GLY A 217
TYR A 223
 None
 0.94A 3af0A-5cl2A:
undetectable		 3af0A-5cl2A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5cl2 SPORULATION-CONTROL
PROTEIN SPO0M
(Bacillus
subtilis) 		4 / 5 TYR A 164
LEU A 215
ASP A 225
GLU A 221
 None
 1.24A 4nkvA-5cl2A:
undetectable		 4nkvA-5cl2A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 5cl2 SPORULATION-CONTROL
PROTEIN SPO0M
(Bacillus
subtilis) 		5 / 10 LEU A 202
LEU A 239
GLY A 201
ALA A 136
PRO A 138
 None
 1.14A 4xj7C-5cl2A:
undetectable
4xj7D-5cl2A:
undetectable		 4xj7C-5cl2A:
20.75
4xj7D-5cl2A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5cl2 SPORULATION-CONTROL
PROTEIN SPO0M
(Bacillus
subtilis) 		3 / 3 ALA A 146
ASN A 149
LEU A 150
 None
 0.28A 5i1nB-5cl2A:
undetectable		 5i1nB-5cl2A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5cl2 SPORULATION-CONTROL
PROTEIN SPO0M
(Bacillus
subtilis) 		3 / 3 ALA A 146
ASN A 149
LEU A 150
 None
 0.39A 5i1oC-5cl2A:
undetectable		 5i1oC-5cl2A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5cl2 SPORULATION-CONTROL
PROTEIN SPO0M
(Bacillus
subtilis) 		3 / 3 ALA A 146
ASN A 149
LEU A 150
 None
 0.37A 5i1pA-5cl2A:
undetectable		 5i1pA-5cl2A:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5cl2 SPORULATION-CONTROL
PROTEIN SPO0M
(Bacillus
subtilis) 		4 / 4 LEU A 191
ARG A 153
ILE A 147
PHE A 152
 None
 1.00A 5kirB-5cl2A:
undetectable		 5kirB-5cl2A:
18.92