SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cmo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 5cmo HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE
(Neisseria
meningitidis) 		3 / 4 LYS A  51
ALA A  54
MET A 110
 None
 1.03A 1hk3A-5cmoA:
undetectable		 1hk3A-5cmoA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA142_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 5cmo HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE
(Neisseria
meningitidis) 		4 / 5 GLU A  87
PRO A  86
ILE A  78
GLY A  79
 None
 1.04A 2qeuA-5cmoA:
undetectable
2qeuC-5cmoA:
undetectable		 2qeuA-5cmoA:
23.65
2qeuC-5cmoA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 5cmo HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE
(Neisseria
meningitidis) 		3 / 3 PRO A  86
PHE A  88
ALA A  55
 None
 0.72A 3itaD-5cmoA:
undetectable		 3itaD-5cmoA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 5cmo HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE
(Neisseria
meningitidis) 		3 / 3 TYR A  48
PHE A  89
ARG A  52
 None
 1.21A 4g19D-5cmoA:
undetectable		 4g19D-5cmoA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_B_SFYB806_0
(SEPIAPTERIN
REDUCTASE)		 5cmo HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE
(Neisseria
meningitidis) 		5 / 11 LEU A  49
LEU A  37
TYR A  48
GLN A  24
ALA A  27
 None
 1.36A 4hwkB-5cmoA:
undetectable		 4hwkB-5cmoA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_C_SFYC804_0
(SEPIAPTERIN
REDUCTASE)		 5cmo HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE
(Neisseria
meningitidis) 		5 / 12 LEU A  49
LEU A  37
TYR A  48
GLN A  24
ALA A  27
 None
 1.37A 4hwkC-5cmoA:
undetectable		 4hwkC-5cmoA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_D_SFYD803_0
(SEPIAPTERIN
REDUCTASE)		 5cmo HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE
(Neisseria
meningitidis) 		5 / 11 LEU A  49
LEU A  37
TYR A  48
GLN A  24
ALA A  27
 None
 1.38A 4hwkD-5cmoA:
undetectable		 4hwkD-5cmoA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 5cmo HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE
(Neisseria
meningitidis) 		4 / 6 PHE A  89
GLY A  77
THR A  32
TYR A  48
 None
 1.16A 6ag0A-5cmoA:
undetectable		 6ag0A-5cmoA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 5cmo HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE
(Neisseria
meningitidis) 		4 / 6 PHE A  89
GLY A  77
THR A  32
TYR A  48
 None
 1.13A 6ag0C-5cmoA:
undetectable		 6ag0C-5cmoA:
26.55