SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cmw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 5cmw EPSIN-5
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 180
TYR A 173
THR A  69
ASN A 118
 GOL  A 201 ( 4.2A)
None
None
None
 1.37A 1afsA-5cmwA:
undetectable		 1afsA-5cmwA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 5cmw EPSIN-5
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 180
TYR A 173
THR A  69
ASN A 118
 GOL  A 201 ( 4.2A)
None
None
None
 1.37A 1afsB-5cmwA:
undetectable		 1afsB-5cmwA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 5cmw EPSIN-5
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 116
VAL A 111
ILE A 112
CYH A 108
LEU A  76
 None
 1.40A 4k36A-5cmwA:
undetectable		 4k36A-5cmwA:
20.41