SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cn1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 5cn1 ADP-RIBOSYLATION
FACTOR-BINDING
PROTEIN GGA1
(Saccharomyces
cerevisiae) 		3 / 3 THR A 552
PRO A 555
TYR A 457
 None
 0.81A 2dxrA-5cn1A:
undetectable		 2dxrA-5cn1A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		 5cn1 ADP-RIBOSYLATION
FACTOR-BINDING
PROTEIN GGA1
(Saccharomyces
cerevisiae) 		4 / 8 SER A 502
PHE A 484
LEU A 447
ASP A 456
 None
 0.83A 3m0wE-5cn1A:
undetectable
3m0wF-5cn1A:
undetectable
3m0wG-5cn1A:
undetectable
3m0wH-5cn1A:
undetectable		 3m0wE-5cn1A:
22.14
3m0wF-5cn1A:
22.14
3m0wG-5cn1A:
22.14
3m0wH-5cn1A:
22.14