SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cnl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 5cnl ICML-LIKE
(Legionella
pneumophila) 		5 / 9 LEU A 149
ILE A  55
ALA A  39
THR A  42
ALA A  89
 None
 1.14A 3mdtA-5cnlA:
undetectable		 3mdtA-5cnlA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)		 5cnl ICML-LIKE
(Legionella
pneumophila) 		4 / 8 ALA A 107
PHE A  59
ALA A  36
THR A  40
 None
 1.12A 3t3sE-5cnlA:
undetectable		 3t3sE-5cnlA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 5cnl ICML-LIKE
(Legionella
pneumophila) 		5 / 10 LEU A 149
ILE A  55
ALA A  39
THR A  42
ALA A  89
 None
 1.07A 4j14A-5cnlA:
undetectable		 4j14A-5cnlA:
16.21