SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5co1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)		 5co1 PROTOCADHERIN-19
ISOFORM 1
(Danio
rerio) 		3 / 3 ASP A 236
ASP A 216
ASP A 269
 CA  A1004 (-3.1A)
None
None
 0.76A 1eizA-5co1A:
undetectable		 1eizA-5co1A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)		 5co1 PROTOCADHERIN-19
ISOFORM 1
(Danio
rerio) 		3 / 3 ASP A 236
ASP A 216
ASP A 269
 CA  A1004 (-3.1A)
None
None
 0.71A 1ej0A-5co1A:
undetectable		 1ej0A-5co1A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 5co1 PROTOCADHERIN-19
ISOFORM 1
(Danio
rerio) 		5 / 11 VAL A 311
ILE A 275
ILE A 235
VAL A 293
PHE A 254
 None
 1.13A 1gx9A-5co1A:
undetectable		 1gx9A-5co1A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)		 5co1 PROTOCADHERIN-19
ISOFORM 1
(Danio
rerio) 		5 / 12 PHE A 215
LEU A 237
VAL A 274
CYH A 307
VAL A 222
 None
 1.31A 2hc4A-5co1A:
undetectable		 2hc4A-5co1A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4USW_A_ACTA1470_0
(ADENYLATE CYCLASE
TYPE 10)		 5co1 PROTOCADHERIN-19
ISOFORM 1
(Danio
rerio) 		4 / 6 LEU A 373
LEU A 347
VAL A 348
PHE A 376
 None
 1.11A 4uswA-5co1A:
undetectable		 4uswA-5co1A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 5co1 PROTOCADHERIN-19
ISOFORM 1
(Danio
rerio) 		3 / 3 ASN A 238
TYR A 252
CYH A 307
 CA  A1004 ( 4.5A)
None
None
 1.06A 5lsuB-5co1A:
undetectable		 5lsuB-5co1A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 5co1 PROTOCADHERIN-19
ISOFORM 1
(Danio
rerio) 		4 / 6 SER A 351
ALA A 320
ALA A 402
SER A 412
 None
 1.00A 6bocA-5co1A:
undetectable
6bocB-5co1A:
undetectable
6bocC-5co1A:
undetectable
6bocD-5co1A:
undetectable		 6bocA-5co1A:
7.51
6bocB-5co1A:
7.51
6bocC-5co1A:
7.51
6bocD-5co1A:
7.51