SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5coa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 5coa IRIDOID SYNTHASE
(Catharanthus
roseus) 		4 / 8 THR A  54
PRO A  55
GLY A  56
LEU A  45
 None
 0.55A 1h4oG-5coaA:
2.2		 1h4oG-5coaA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 5coa IRIDOID SYNTHASE
(Catharanthus
roseus) 		5 / 12 TYR A  62
ASP A 100
ILE A 101
LEU A  33
VAL A  34
 None
 1.21A 1r30A-5coaA:
undetectable		 1r30A-5coaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_A_DAHA2_1
(RANASMURFIN)		 5coa IRIDOID SYNTHASE
(Catharanthus
roseus) 		5 / 9 ALA A 251
ALA A 255
PHE A 364
GLY A 366
CYH A 274
 None
 1.50A 2vh3A-5coaA:
undetectable		 2vh3A-5coaA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 5coa IRIDOID SYNTHASE
(Catharanthus
roseus) 		4 / 7 THR A  54
PRO A  55
GLY A  56
LEU A  45
 None
 0.58A 2vl2B-5coaA:
2.3		 2vl2B-5coaA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 5coa IRIDOID SYNTHASE
(Catharanthus
roseus) 		4 / 5 GLN A  82
ILE A  81
TYR A  80
GLU A  79
 None
 1.03A 4a99D-5coaA:
5.9		 4a99D-5coaA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		 5coa IRIDOID SYNTHASE
(Catharanthus
roseus) 		4 / 7 LEU A  49
VAL A  48
LYS A  29
TYR A  28
 None
 0.97A 4lb2A-5coaA:
undetectable		 4lb2A-5coaA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF8_A_LBHA2004_1
(HDAC6 PROTEIN)		 5coa IRIDOID SYNTHASE
(Catharanthus
roseus) 		5 / 12 ASP A  53
PRO A  55
HIS A 199
HIS A 257
PHE A 364
 None
 1.30A 5ef8A-5coaA:
4.1		 5ef8A-5coaA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5coa IRIDOID SYNTHASE
(Catharanthus
roseus) 		5 / 12 ILE A 145
GLU A 256
ALA A 267
VAL A 271
GLY A 363
 None
 1.08A 5igjA-5coaA:
undetectable		 5igjA-5coaA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5coa IRIDOID SYNTHASE
(Catharanthus
roseus) 		6 / 12 ILE A 145
GLU A 256
ALA A 267
VAL A 271
LEU A 362
GLY A 363
 None
 1.27A 5igtA-5coaA:
undetectable		 5igtA-5coaA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_A_SALA505_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 5coa IRIDOID SYNTHASE
(Catharanthus
roseus) 		4 / 8 PHE A 207
MET A 381
TRP A 320
THR A 332
 None
 1.41A 5u6nA-5coaA:
5.6		 5u6nA-5coaA:
22.15