SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cog'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 5cog IRC4
(Saccharomyces
cerevisiae) 		3 / 3 ALA A  75
VAL A  71
TRP A 133
 None
 0.90A 1tkqB-5cogA:
undetectable		 1tkqB-5cogA:
8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 5cog IRC4
(Saccharomyces
cerevisiae) 		4 / 9 TYR A  87
PHE A 157
LYS A 160
ILE A 148
 None
None
CL  A 202 (-4.9A)
None
 1.35A 4jvlA-5cogA:
undetectable		 4jvlA-5cogA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)		 5cog IRC4
(Saccharomyces
cerevisiae) 		5 / 11 VAL A 142
ILE A 146
ASN A 149
THR A 150
ILE A 117
 None
 1.20A 5y80A-5cogA:
undetectable		 5y80A-5cogA:
17.39