SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cow'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1V_A_H4BA700_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.34A 1d1vA-5cowA:
undetectable
1d1vB-5cowA:
undetectable
1d1vA-5cowA:
20.85
1d1vB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1V_B_H4BB701_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.36A 1d1vA-5cowA:
undetectable
1d1vB-5cowA:
undetectable
1d1vA-5cowA:
20.85
1d1vB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1W_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.36A 1d1wA-5cowA:
undetectable
1d1wB-5cowA:
undetectable
1d1wA-5cowA:
20.85
1d1wB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1X_A_H4BA600_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME DOMAIN)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.35A 1d1xA-5cowA:
undetectable
1d1xB-5cowA:
undetectable
1d1xA-5cowA:
20.85
1d1xB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1X_B_H4BB601_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME DOMAIN)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.35A 1d1xA-5cowA:
undetectable
1d1xB-5cowA:
undetectable
1d1xA-5cowA:
20.85
1d1xB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DM8_A_H4BA1600_1
(NITRIC OXIDE
SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.35A 1dm8A-5cowA:
undetectable
1dm8B-5cowA:
undetectable
1dm8A-5cowA:
20.85
1dm8B-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_B_BHSB2610_1
(NITRIC OXIDE
SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.37A 1dmiA-5cowA:
undetectable
1dmiB-5cowA:
undetectable
1dmiA-5cowA:
20.85
1dmiB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.33A 1nseA-5cowA:
undetectable
1nseB-5cowA:
undetectable
1nseA-5cowA:
20.85
1nseB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.35A 1nseA-5cowA:
undetectable
1nseB-5cowA:
undetectable
1nseA-5cowA:
20.85
1nseB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.37A 1p6lA-5cowA:
undetectable
1p6lB-5cowA:
undetectable
1p6lA-5cowA:
20.95
1p6lB-5cowA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.38A 1p6lA-5cowA:
undetectable
1p6lB-5cowA:
undetectable
1p6lA-5cowA:
20.95
1p6lB-5cowA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.35A 1p6mA-5cowA:
undetectable
1p6mB-5cowA:
undetectable
1p6mA-5cowA:
20.95
1p6mB-5cowA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.36A 1p6mA-5cowA:
undetectable
1p6mB-5cowA:
undetectable
1p6mA-5cowA:
20.95
1p6mB-5cowA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6N_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.38A 1p6nA-5cowA:
undetectable
1p6nB-5cowA:
1.7
1p6nA-5cowA:
20.95
1p6nB-5cowA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q2O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.34A 1q2oA-5cowA:
undetectable
1q2oB-5cowA:
1.6
1q2oA-5cowA:
21.53
1q2oB-5cowA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q2O_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.34A 1q2oA-5cowA:
undetectable
1q2oB-5cowA:
1.6
1q2oA-5cowA:
21.53
1q2oB-5cowA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS8_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.36A 1rs8A-5cowA:
undetectable
1rs8B-5cowA:
1.6
1rs8A-5cowA:
21.53
1rs8B-5cowA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS8_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.37A 1rs8A-5cowA:
undetectable
1rs8B-5cowA:
1.6
1rs8A-5cowA:
21.53
1rs8B-5cowA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS9_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.38A 1rs9A-5cowA:
1.3
1rs9B-5cowA:
undetectable
1rs9A-5cowA:
21.53
1rs9B-5cowA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS9_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.36A 1rs9A-5cowA:
1.3
1rs9B-5cowA:
undetectable
1rs9A-5cowA:
21.53
1rs9B-5cowA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 LEU A 434
ARG A 403
THR A 399
LEU A 397
None
1.03A 1v54A-5cowA:
undetectable
1v54J-5cowA:
undetectable
1v54A-5cowA:
16.63
1v54J-5cowA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZS_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.33A 1zzsA-5cowA:
1.7
1zzsB-5cowA:
undetectable
1zzsA-5cowA:
21.53
1zzsB-5cowA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZS_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.36A 1zzsA-5cowA:
1.7
1zzsB-5cowA:
undetectable
1zzsA-5cowA:
21.53
1zzsB-5cowA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 LEU A 434
ARG A 403
THR A 399
LEU A 397
None
1.06A 2dyrA-5cowA:
undetectable
2dyrJ-5cowA:
undetectable
2dyrA-5cowA:
16.63
2dyrJ-5cowA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
5 / 9 LEU A 434
ILE A 317
PHE A 439
LEU A 461
ILE A 436
None
1.13A 2f78A-5cowA:
undetectable
2f78A-5cowA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
5 / 9 LEU A 434
ILE A 317
PHE A 439
LEU A 461
ILE A 436
None
1.08A 2f78B-5cowA:
undetectable
2f78B-5cowA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
5 / 9 LEU A 434
ILE A 317
PHE A 439
LEU A 461
ILE A 436
None
1.17A 2f7aA-5cowA:
undetectable
2f7aA-5cowA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
5 / 10 LEU A 434
ILE A 317
PHE A 439
LEU A 461
ILE A 436
None
1.11A 2f8dA-5cowA:
undetectable
2f8dA-5cowA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
5 / 10 LEU A 434
ILE A 317
PHE A 439
LEU A 461
ILE A 436
None
1.08A 2f8dB-5cowA:
undetectable
2f8dB-5cowA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX2_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.34A 2hx2A-5cowA:
undetectable
2hx2B-5cowA:
undetectable
2hx2A-5cowA:
21.53
2hx2B-5cowA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX2_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.36A 2hx2A-5cowA:
undetectable
2hx2B-5cowA:
undetectable
2hx2A-5cowA:
21.53
2hx2B-5cowA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.36A 2nseA-5cowA:
undetectable
2nseB-5cowA:
undetectable
2nseA-5cowA:
20.85
2nseB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 LEU A 434
ARG A 403
THR A 399
LEU A 397
None
1.08A 2zxwA-5cowA:
undetectable
2zxwJ-5cowA:
undetectable
2zxwA-5cowA:
16.63
2zxwJ-5cowA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 7 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.28A 3dqrA-5cowA:
undetectable
3dqrB-5cowA:
undetectable
3dqrA-5cowA:
20.79
3dqrB-5cowA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.31A 3dqsA-5cowA:
1.7
3dqsB-5cowA:
undetectable
3dqsA-5cowA:
21.53
3dqsB-5cowA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.33A 3dqsA-5cowA:
1.7
3dqsB-5cowA:
undetectable
3dqsA-5cowA:
21.53
3dqsB-5cowA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.34A 3dqtA-5cowA:
undetectable
3dqtB-5cowA:
1.6
3dqtA-5cowA:
21.53
3dqtB-5cowA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 7 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.37A 3dqtA-5cowA:
undetectable
3dqtB-5cowA:
1.6
3dqtA-5cowA:
21.53
3dqtB-5cowA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWX_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.32A 3jwxA-5cowA:
undetectable
3jwxB-5cowA:
1.7
3jwxA-5cowA:
20.85
3jwxB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.31A 3jwyA-5cowA:
undetectable
3jwyB-5cowA:
1.5
3jwyA-5cowA:
20.85
3jwyB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.32A 3jwyA-5cowA:
undetectable
3jwyB-5cowA:
1.5
3jwyA-5cowA:
20.85
3jwyB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.34A 3jwzA-5cowA:
1.7
3jwzB-5cowA:
undetectable
3jwzA-5cowA:
20.85
3jwzB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.33A 3jwzA-5cowA:
1.7
3jwzB-5cowA:
undetectable
3jwzA-5cowA:
20.85
3jwzB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 7 PHE A 309
GLY A 347
PHE A 340
PHE A 442
None
0.89A 3ko0D-5cowA:
undetectable
3ko0E-5cowA:
undetectable
3ko0D-5cowA:
17.81
3ko0E-5cowA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 7 PHE A 309
GLY A 347
PHE A 340
PHE A 442
None
0.90A 3ko0M-5cowA:
undetectable
3ko0P-5cowA:
undetectable
3ko0M-5cowA:
17.81
3ko0P-5cowA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5P_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.33A 3n5pA-5cowA:
1.1
3n5pB-5cowA:
undetectable
3n5pA-5cowA:
20.85
3n5pB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Q_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.36A 3n5qA-5cowA:
undetectable
3n5qB-5cowA:
1.6
3n5qA-5cowA:
20.85
3n5qB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5R_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.36A 3n5rA-5cowA:
undetectable
3n5rB-5cowA:
undetectable
3n5rA-5cowA:
20.85
3n5rB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5R_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.32A 3n5rA-5cowA:
undetectable
3n5rB-5cowA:
undetectable
3n5rA-5cowA:
20.85
3n5rB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5S_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.32A 3n5sA-5cowA:
1.7
3n5sB-5cowA:
1.7
3n5sA-5cowA:
20.85
3n5sB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5S_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.33A 3n5sA-5cowA:
1.7
3n5sB-5cowA:
1.7
3n5sA-5cowA:
20.85
3n5sB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 7 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.36A 3n5tA-5cowA:
undetectable
3n5tB-5cowA:
undetectable
3n5tA-5cowA:
20.85
3n5tB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.32A 3n6eA-5cowA:
undetectable
3n6eB-5cowA:
undetectable
3n6eA-5cowA:
20.85
3n6eB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.34A 3n6eA-5cowA:
undetectable
3n6eB-5cowA:
undetectable
3n6eA-5cowA:
20.85
3n6eB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6F_A_H4BA600_1
('NITRIC OXIDE
SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.31A 3n6fA-5cowA:
undetectable
3n6fB-5cowA:
1.7
3n6fA-5cowA:
20.85
3n6fB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6F_B_H4BB600_1
('NITRIC OXIDE
SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.33A 3n6fA-5cowA:
undetectable
3n6fB-5cowA:
1.7
3n6fA-5cowA:
20.85
3n6fB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6G_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.34A 3n6gA-5cowA:
undetectable
3n6gB-5cowA:
undetectable
3n6gA-5cowA:
20.85
3n6gB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6G_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.32A 3n6gA-5cowA:
undetectable
3n6gB-5cowA:
undetectable
3n6gA-5cowA:
20.85
3n6gB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.32A 3nleA-5cowA:
1.7
3nleB-5cowA:
1.7
3nleA-5cowA:
20.85
3nleB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLF_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.29A 3nlfA-5cowA:
undetectable
3nlfB-5cowA:
1.6
3nlfA-5cowA:
20.85
3nlfB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.32A 3nlgA-5cowA:
undetectable
3nlgB-5cowA:
1.7
3nlgA-5cowA:
20.85
3nlgB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.33A 3nlgA-5cowA:
undetectable
3nlgB-5cowA:
1.7
3nlgA-5cowA:
20.85
3nlgB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLH_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.32A 3nlhA-5cowA:
undetectable
3nlhB-5cowA:
1.6
3nlhA-5cowA:
20.85
3nlhB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLI_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.32A 3nliA-5cowA:
1.7
3nliB-5cowA:
undetectable
3nliA-5cowA:
20.85
3nliB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 7 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.32A 3nlpA-5cowA:
undetectable
3nlpB-5cowA:
undetectable
3nlpA-5cowA:
20.79
3nlpB-5cowA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLU_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.34A 3nluA-5cowA:
undetectable
3nluB-5cowA:
1.6
3nluA-5cowA:
20.85
3nluB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NOS_A_H4BA511_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.35A 3nosA-5cowA:
1.6
3nosB-5cowA:
1.6
3nosA-5cowA:
21.02
3nosB-5cowA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NOS_B_H4BB1011_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.33A 3nosA-5cowA:
1.6
3nosB-5cowA:
1.6
3nosA-5cowA:
21.02
3nosB-5cowA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNH_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.34A 3pnhA-5cowA:
1.7
3pnhB-5cowA:
1.5
3pnhA-5cowA:
21.53
3pnhB-5cowA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNH_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.32A 3pnhA-5cowA:
1.7
3pnhB-5cowA:
1.5
3pnhA-5cowA:
21.53
3pnhB-5cowA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQO_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.31A 3rqoA-5cowA:
undetectable
3rqoB-5cowA:
undetectable
3rqoA-5cowA:
20.90
3rqoB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQO_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.34A 3rqoA-5cowA:
undetectable
3rqoB-5cowA:
undetectable
3rqoA-5cowA:
20.90
3rqoB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQP_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.33A 3rqpA-5cowA:
undetectable
3rqpB-5cowA:
1.7
3rqpA-5cowA:
20.90
3rqpB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C3A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.31A 4c3aA-5cowA:
undetectable
4c3aB-5cowA:
undetectable
4c3aA-5cowA:
20.90
4c3aB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C3A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.33A 4c3aA-5cowA:
undetectable
4c3aB-5cowA:
undetectable
4c3aA-5cowA:
20.90
4c3aB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAR_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.33A 4carA-5cowA:
undetectable
4carB-5cowA:
undetectable
4carA-5cowA:
20.90
4carB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAR_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.32A 4carA-5cowA:
undetectable
4carB-5cowA:
undetectable
4carA-5cowA:
20.90
4carB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CFT_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.34A 4cftA-5cowA:
undetectable
4cftB-5cowA:
undetectable
4cftA-5cowA:
20.90
4cftB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CFT_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.35A 4cftA-5cowA:
undetectable
4cftB-5cowA:
undetectable
4cftA-5cowA:
20.90
4cftB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.29A 4ctyA-5cowA:
undetectable
4ctyB-5cowA:
1.7
4ctyA-5cowA:
20.90
4ctyB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.32A 4ctyA-5cowA:
undetectable
4ctyB-5cowA:
1.7
4ctyA-5cowA:
20.90
4ctyB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.37A 4ctzA-5cowA:
undetectable
4ctzB-5cowA:
undetectable
4ctzA-5cowA:
20.90
4ctzB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.32A 4ctzA-5cowA:
undetectable
4ctzB-5cowA:
undetectable
4ctzA-5cowA:
20.90
4ctzB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.33A 4cu0A-5cowA:
1.4
4cu0B-5cowA:
1.6
4cu0A-5cowA:
20.90
4cu0B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.31A 4cu0A-5cowA:
1.4
4cu0B-5cowA:
1.6
4cu0A-5cowA:
20.90
4cu0B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU1_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.34A 4cu1A-5cowA:
1.7
4cu1B-5cowA:
undetectable
4cu1A-5cowA:
20.90
4cu1B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU1_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.35A 4cu1A-5cowA:
1.7
4cu1B-5cowA:
undetectable
4cu1A-5cowA:
20.90
4cu1B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWV_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.30A 4cwvA-5cowA:
undetectable
4cwvB-5cowA:
1.3
4cwvA-5cowA:
20.90
4cwvB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWV_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.35A 4cwvA-5cowA:
undetectable
4cwvB-5cowA:
1.3
4cwvA-5cowA:
20.90
4cwvB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWW_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.31A 4cwwA-5cowA:
undetectable
4cwwB-5cowA:
undetectable
4cwwA-5cowA:
20.90
4cwwB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWW_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.33A 4cwwA-5cowA:
undetectable
4cwwB-5cowA:
undetectable
4cwwA-5cowA:
20.90
4cwwB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWX_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.30A 4cwxA-5cowA:
undetectable
4cwxB-5cowA:
1.3
4cwxA-5cowA:
20.90
4cwxB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 7 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.31A 4cwxA-5cowA:
undetectable
4cwxB-5cowA:
undetectable
4cwxA-5cowA:
20.90
4cwxB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 7 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.33A 4cwyA-5cowA:
undetectable
4cwyB-5cowA:
undetectable
4cwyA-5cowA:
20.90
4cwyB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 7 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.31A 4cwyA-5cowA:
undetectable
4cwyB-5cowA:
undetectable
4cwyA-5cowA:
20.90
4cwyB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.31A 4cwzA-5cowA:
undetectable
4cwzB-5cowA:
undetectable
4cwzA-5cowA:
20.76
4cwzB-5cowA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.31A 4cwzA-5cowA:
undetectable
4cwzB-5cowA:
undetectable
4cwzA-5cowA:
20.76
4cwzB-5cowA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.31A 4cx0A-5cowA:
undetectable
4cx0B-5cowA:
1.7
4cx0A-5cowA:
20.76
4cx0B-5cowA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX0_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.34A 4cx0A-5cowA:
undetectable
4cx0B-5cowA:
1.7
4cx0A-5cowA:
20.76
4cx0B-5cowA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1O_A_H4BA1481_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.37A 4d1oA-5cowA:
undetectable
4d1oB-5cowA:
undetectable
4d1oA-5cowA:
21.97
4d1oB-5cowA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1O_B_H4BB1481_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.35A 4d1oA-5cowA:
undetectable
4d1oB-5cowA:
undetectable
4d1oA-5cowA:
21.97
4d1oB-5cowA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.31A 4d33A-5cowA:
undetectable
4d33B-5cowA:
undetectable
4d33A-5cowA:
20.90
4d33B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.32A 4d33A-5cowA:
undetectable
4d33B-5cowA:
undetectable
4d33A-5cowA:
20.90
4d33B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D34_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.33A 4d34A-5cowA:
undetectable
4d34B-5cowA:
undetectable
4d34A-5cowA:
20.90
4d34B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D35_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.34A 4d35A-5cowA:
undetectable
4d35B-5cowA:
undetectable
4d35A-5cowA:
20.90
4d35B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D36_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.31A 4d36A-5cowA:
1.3
4d36B-5cowA:
1.6
4d36A-5cowA:
20.90
4d36B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D36_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.33A 4d36A-5cowA:
1.3
4d36B-5cowA:
1.6
4d36A-5cowA:
20.90
4d36B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D37_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.33A 4d37A-5cowA:
undetectable
4d37B-5cowA:
undetectable
4d37A-5cowA:
20.90
4d37B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D37_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.31A 4d37A-5cowA:
undetectable
4d37B-5cowA:
undetectable
4d37A-5cowA:
20.90
4d37B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D38_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.35A 4d38A-5cowA:
undetectable
4d38B-5cowA:
undetectable
4d38A-5cowA:
20.90
4d38B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D38_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.31A 4d38A-5cowA:
undetectable
4d38B-5cowA:
undetectable
4d38A-5cowA:
20.90
4d38B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.33A 4d39A-5cowA:
1.3
4d39B-5cowA:
undetectable
4d39A-5cowA:
20.90
4d39B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.36A 4d39A-5cowA:
1.3
4d39B-5cowA:
undetectable
4d39A-5cowA:
20.90
4d39B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.32A 4d3aA-5cowA:
undetectable
4d3aB-5cowA:
undetectable
4d3aA-5cowA:
20.90
4d3aB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.30A 4d3aA-5cowA:
undetectable
4d3aB-5cowA:
undetectable
4d3aA-5cowA:
20.90
4d3aB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_A_H4BA502_1
(SUBUNIT A)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.33A 4imxA-5cowA:
undetectable
4imxB-5cowA:
undetectable
4imxA-5cowA:
20.95
4imxB-5cowA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_B_H4BB502_1
(SUBUNIT A)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.34A 4imxA-5cowA:
undetectable
4imxB-5cowA:
undetectable
4imxA-5cowA:
20.95
4imxB-5cowA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSK_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.28A 4jskA-5cowA:
undetectable
4jskB-5cowA:
1.3
4jskA-5cowA:
20.90
4jskB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSL_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.34A 4jslA-5cowA:
undetectable
4jslB-5cowA:
1.7
4jslA-5cowA:
20.90
4jslB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSL_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.33A 4jslA-5cowA:
undetectable
4jslB-5cowA:
1.7
4jslA-5cowA:
20.90
4jslB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSM_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.31A 4jsmA-5cowA:
1.3
4jsmB-5cowA:
undetectable
4jsmA-5cowA:
20.90
4jsmB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5H_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.32A 4k5hA-5cowA:
undetectable
4k5hB-5cowA:
1.7
4k5hA-5cowA:
20.90
4k5hB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5H_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.34A 4k5hA-5cowA:
undetectable
4k5hB-5cowA:
1.7
4k5hA-5cowA:
20.90
4k5hB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5I_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.32A 4k5iA-5cowA:
undetectable
4k5iB-5cowA:
undetectable
4k5iA-5cowA:
20.90
4k5iB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5I_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.35A 4k5iA-5cowA:
undetectable
4k5iB-5cowA:
undetectable
4k5iA-5cowA:
20.90
4k5iB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.36A 4k5jA-5cowA:
undetectable
4k5jB-5cowA:
undetectable
4k5jA-5cowA:
20.90
4k5jB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 7 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.37A 4k5jA-5cowA:
undetectable
4k5jB-5cowA:
undetectable
4k5jA-5cowA:
20.90
4k5jB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5K_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.34A 4k5kA-5cowA:
1.5
4k5kB-5cowA:
undetectable
4k5kA-5cowA:
20.90
4k5kB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5K_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.33A 4k5kA-5cowA:
1.5
4k5kB-5cowA:
undetectable
4k5kA-5cowA:
20.90
4k5kB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCP_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.29A 4kcpA-5cowA:
undetectable
4kcpB-5cowA:
1.7
4kcpA-5cowA:
20.90
4kcpB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCP_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.32A 4kcpA-5cowA:
undetectable
4kcpB-5cowA:
1.7
4kcpA-5cowA:
20.90
4kcpB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCQ_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.33A 4kcqA-5cowA:
1.4
4kcqB-5cowA:
undetectable
4kcqA-5cowA:
20.90
4kcqB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCQ_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.34A 4kcqA-5cowA:
1.4
4kcqB-5cowA:
undetectable
4kcqA-5cowA:
20.90
4kcqB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCR_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.32A 4kcrA-5cowA:
1.3
4kcrB-5cowA:
undetectable
4kcrA-5cowA:
20.90
4kcrB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCR_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.36A 4kcrA-5cowA:
1.3
4kcrB-5cowA:
undetectable
4kcrA-5cowA:
20.90
4kcrB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCS_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.31A 4kcsA-5cowA:
1.3
4kcsB-5cowA:
undetectable
4kcsA-5cowA:
20.90
4kcsB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCS_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.31A 4kcsA-5cowA:
1.3
4kcsB-5cowA:
undetectable
4kcsA-5cowA:
20.90
4kcsB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUW_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.33A 4luwA-5cowA:
undetectable
4luwB-5cowA:
undetectable
4luwA-5cowA:
20.95
4luwB-5cowA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_A_AERA602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 8 ALA A 280
ILE A 361
GLY A 311
VAL A 372
None
0.70A 4r20A-5cowA:
undetectable
4r20A-5cowA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.32A 4uh7A-5cowA:
undetectable
4uh7B-5cowA:
undetectable
4uh7A-5cowA:
20.90
4uh7B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.32A 4uh7A-5cowA:
undetectable
4uh7B-5cowA:
undetectable
4uh7A-5cowA:
20.90
4uh7B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH8_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.33A 4uh8A-5cowA:
undetectable
4uh8B-5cowA:
undetectable
4uh8A-5cowA:
20.90
4uh8B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH8_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.32A 4uh8A-5cowA:
undetectable
4uh8B-5cowA:
undetectable
4uh8A-5cowA:
20.90
4uh8B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH9_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.30A 4uh9A-5cowA:
1.7
4uh9B-5cowA:
undetectable
4uh9A-5cowA:
20.90
4uh9B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH9_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.31A 4uh9A-5cowA:
1.7
4uh9B-5cowA:
undetectable
4uh9A-5cowA:
20.90
4uh9B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHA_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.32A 4uhaA-5cowA:
undetectable
4uhaB-5cowA:
undetectable
4uhaA-5cowA:
20.90
4uhaB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHA_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.32A 4uhaA-5cowA:
undetectable
4uhaB-5cowA:
undetectable
4uhaA-5cowA:
20.90
4uhaB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPQ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.35A 4upqA-5cowA:
undetectable
4upqB-5cowA:
undetectable
4upqA-5cowA:
20.90
4upqB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPQ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.34A 4upqA-5cowA:
undetectable
4upqB-5cowA:
undetectable
4upqA-5cowA:
20.90
4upqB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPR_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.33A 4uprA-5cowA:
undetectable
4uprB-5cowA:
1.7
4uprA-5cowA:
20.90
4uprB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPR_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.33A 4uprA-5cowA:
undetectable
4uprB-5cowA:
1.7
4uprA-5cowA:
20.90
4uprB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPS_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.34A 4upsA-5cowA:
undetectable
4upsB-5cowA:
1.3
4upsA-5cowA:
20.90
4upsB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPS_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.35A 4upsA-5cowA:
undetectable
4upsB-5cowA:
1.3
4upsA-5cowA:
20.90
4upsB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPT_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.32A 4uptA-5cowA:
undetectable
4uptB-5cowA:
undetectable
4uptA-5cowA:
20.90
4uptB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADJ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.33A 5adjA-5cowA:
undetectable
5adjB-5cowA:
undetectable
5adjA-5cowA:
20.90
5adjB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADJ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.34A 5adjA-5cowA:
undetectable
5adjB-5cowA:
undetectable
5adjA-5cowA:
20.90
5adjB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADK_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.32A 5adkA-5cowA:
undetectable
5adkB-5cowA:
undetectable
5adkA-5cowA:
20.90
5adkB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADK_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.35A 5adkA-5cowA:
undetectable
5adkB-5cowA:
undetectable
5adkA-5cowA:
20.90
5adkB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.32A 5adlA-5cowA:
undetectable
5adlB-5cowA:
1.6
5adlA-5cowA:
20.90
5adlB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 7 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.32A 5adlA-5cowA:
undetectable
5adlB-5cowA:
1.6
5adlA-5cowA:
20.90
5adlB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.32A 5admA-5cowA:
undetectable
5admB-5cowA:
1.7
5admA-5cowA:
20.90
5admB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.33A 5admA-5cowA:
undetectable
5admB-5cowA:
1.7
5admA-5cowA:
20.90
5admB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADN_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.32A 5adnA-5cowA:
undetectable
5adnB-5cowA:
undetectable
5adnA-5cowA:
20.90
5adnB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADN_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.35A 5adnA-5cowA:
undetectable
5adnB-5cowA:
undetectable
5adnA-5cowA:
20.90
5adnB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ2_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.33A 5fj2A-5cowA:
undetectable
5fj2B-5cowA:
undetectable
5fj2A-5cowA:
20.90
5fj2B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ2_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.33A 5fj2A-5cowA:
undetectable
5fj2B-5cowA:
undetectable
5fj2A-5cowA:
20.90
5fj2B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.34A 5fj3A-5cowA:
undetectable
5fj3B-5cowA:
1.7
5fj3A-5cowA:
20.90
5fj3B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 7 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.35A 5fj3A-5cowA:
undetectable
5fj3B-5cowA:
1.7
5fj3A-5cowA:
20.90
5fj3B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.33A 5fvyA-5cowA:
undetectable
5fvyB-5cowA:
undetectable
5fvyA-5cowA:
20.90
5fvyB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.33A 5fvyA-5cowA:
undetectable
5fvyB-5cowA:
undetectable
5fvyA-5cowA:
20.90
5fvyB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVZ_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.32A 5fvzA-5cowA:
undetectable
5fvzB-5cowA:
1.7
5fvzA-5cowA:
20.90
5fvzB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVZ_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.35A 5fvzA-5cowA:
undetectable
5fvzB-5cowA:
1.7
5fvzA-5cowA:
20.90
5fvzB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
3 / 3 TRP A 343
ILE A 317
SER A 438
None
0.85A 5gqbA-5cowA:
undetectable
5gqbA-5cowA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNX_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
5 / 12 VAL A 303
PHE A 368
LEU A 272
THR A 271
ARG A 292
None
None
None
None
SO4  A 502 (-4.3A)
1.30A 5hnxB-5cowA:
undetectable
5hnxB-5cowA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.30A 5uo8A-5cowA:
undetectable
5uo8B-5cowA:
0.0
5uo8A-5cowA:
21.97
5uo8B-5cowA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.31A 5uo8C-5cowA:
0.0
5uo8D-5cowA:
0.0
5uo8C-5cowA:
21.97
5uo8D-5cowA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.32A 5uo8C-5cowA:
undetectable
5uo8D-5cowA:
0.0
5uo8C-5cowA:
21.97
5uo8D-5cowA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.41A 5uo9A-5cowA:
0.0
5uo9B-5cowA:
0.0
5uo9A-5cowA:
21.97
5uo9B-5cowA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 7 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.34A 5uo9A-5cowA:
undetectable
5uo9B-5cowA:
undetectable
5uo9A-5cowA:
21.97
5uo9B-5cowA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.33A 5uo9C-5cowA:
undetectable
5uo9D-5cowA:
0.0
5uo9C-5cowA:
21.97
5uo9D-5cowA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 7 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.31A 5uo9C-5cowA:
undetectable
5uo9D-5cowA:
undetectable
5uo9C-5cowA:
21.97
5uo9D-5cowA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOD_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.32A 5uodA-5cowA:
undetectable
5uodB-5cowA:
undetectable
5uodA-5cowA:
20.90
5uodB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOD_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.34A 5uodA-5cowA:
undetectable
5uodB-5cowA:
undetectable
5uodA-5cowA:
20.90
5uodB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV6_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.29A 5vv6A-5cowA:
undetectable
5vv6B-5cowA:
undetectable
5vv6A-5cowA:
20.90
5vv6B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV6_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.32A 5vv6A-5cowA:
undetectable
5vv6B-5cowA:
undetectable
5vv6A-5cowA:
20.90
5vv6B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.33A 5vv7A-5cowA:
undetectable
5vv7B-5cowA:
1.7
5vv7A-5cowA:
20.90
5vv7B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 7 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.36A 5vv7A-5cowA:
undetectable
5vv7B-5cowA:
1.7
5vv7A-5cowA:
20.90
5vv7B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV8_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.30A 5vv8A-5cowA:
undetectable
5vv8B-5cowA:
undetectable
5vv8A-5cowA:
20.90
5vv8B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV8_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.34A 5vv8A-5cowA:
undetectable
5vv8B-5cowA:
undetectable
5vv8A-5cowA:
20.90
5vv8B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV9_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 7 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.33A 5vv9A-5cowA:
undetectable
5vv9B-5cowA:
1.5
5vv9A-5cowA:
20.90
5vv9B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV9_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.34A 5vv9A-5cowA:
undetectable
5vv9B-5cowA:
1.5
5vv9A-5cowA:
20.90
5vv9B-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVA_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 7 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.33A 5vvaA-5cowA:
undetectable
5vvaB-5cowA:
undetectable
5vvaA-5cowA:
20.90
5vvaB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVA_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.34A 5vvaA-5cowA:
undetectable
5vvaB-5cowA:
undetectable
5vvaA-5cowA:
20.90
5vvaB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.30A 5vvbA-5cowA:
0.0
5vvbB-5cowA:
0.0
5vvbA-5cowA:
21.97
5vvbB-5cowA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.29A 5vvbC-5cowA:
undetectable
5vvbD-5cowA:
0.0
5vvbC-5cowA:
21.97
5vvbD-5cowA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.33A 5vvcA-5cowA:
0.0
5vvcB-5cowA:
0.0
5vvcA-5cowA:
21.97
5vvcB-5cowA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.34A 5vvcC-5cowA:
0.0
5vvcD-5cowA:
undetectable
5vvcC-5cowA:
21.97
5vvcD-5cowA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 7 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.29A 5vvdA-5cowA:
undetectable
5vvdB-5cowA:
undetectable
5vvdA-5cowA:
21.97
5vvdB-5cowA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.30A 5vvdC-5cowA:
0.5
5vvdD-5cowA:
0.0
5vvdC-5cowA:
21.97
5vvdD-5cowA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVG_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.28A 5vvgA-5cowA:
1.2
5vvgB-5cowA:
undetectable
5vvgA-5cowA:
20.90
5vvgB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVG_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.32A 5vvgA-5cowA:
1.2
5vvgB-5cowA:
undetectable
5vvgA-5cowA:
20.90
5vvgB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.29A 5vvnA-5cowA:
undetectable
5vvnB-5cowA:
undetectable
5vvnA-5cowA:
20.90
5vvnB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 7 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.33A 5vvnA-5cowA:
undetectable
5vvnB-5cowA:
undetectable
5vvnA-5cowA:
20.90
5vvnB-5cowA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 7 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.36A 6av7A-5cowA:
undetectable
6av7B-5cowA:
undetectable
6av7A-5cowA:
13.25
6av7B-5cowA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.31A 6av7A-5cowA:
undetectable
6av7B-5cowA:
0.0
6av7A-5cowA:
13.25
6av7B-5cowA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.33A 6av7C-5cowA:
0.5
6av7D-5cowA:
undetectable
6av7C-5cowA:
13.25
6av7D-5cowA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.33A 6av7C-5cowA:
0.5
6av7D-5cowA:
0.0
6av7C-5cowA:
13.25
6av7D-5cowA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_A_H4BA502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.34A 6cieA-5cowA:
0.0
6cieB-5cowA:
undetectable
6cieA-5cowA:
13.25
6cieB-5cowA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_B_H4BB502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 7 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.30A 6cieA-5cowA:
0.0
6cieB-5cowA:
undetectable
6cieA-5cowA:
13.25
6cieB-5cowA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_C_H4BC502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.33A 6cieC-5cowA:
undetectable
6cieD-5cowA:
0.0
6cieC-5cowA:
13.25
6cieD-5cowA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_D_H4BD502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.33A 6cieC-5cowA:
undetectable
6cieD-5cowA:
0.0
6cieC-5cowA:
13.25
6cieD-5cowA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIF_A_H4BA502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.36A 6cifA-5cowA:
0.0
6cifB-5cowA:
0.0
6cifA-5cowA:
13.25
6cifB-5cowA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIF_B_H4BB502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.31A 6cifA-5cowA:
0.0
6cifB-5cowA:
undetectable
6cifA-5cowA:
13.25
6cifB-5cowA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIF_C_H4BC502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 7 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.31A 6cifC-5cowA:
undetectable
6cifD-5cowA:
undetectable
6cifC-5cowA:
13.25
6cifD-5cowA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIF_D_H4BD502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.36A 6cifC-5cowA:
undetectable
6cifD-5cowA:
undetectable
6cifC-5cowA:
13.25
6cifD-5cowA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
8NSE_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.37A 8nseA-5cowA:
undetectable
8nseB-5cowA:
undetectable
8nseA-5cowA:
20.85
8nseB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
9NSE_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 VAL A 409
TRP A 407
PHE A 404
GLU A 410
None
1.35A 9nseA-5cowA:
undetectable
9nseB-5cowA:
undetectable
9nseA-5cowA:
20.85
9nseB-5cowA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
9NSE_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
5cow PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
remanei)
4 / 6 TRP A 407
PHE A 404
GLU A 410
VAL A 409
None
1.35A 9nseA-5cowA:
undetectable
9nseB-5cowA:
undetectable
9nseA-5cowA:
20.85
9nseB-5cowA:
20.85