SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cpc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5cpc SECRETED EFFECTOR
PROTEIN SOPD
(Salmonella
enterica) 		4 / 7 GLN A 235
TYR A 234
TYR A 281
ILE A 218
 None
 1.32A 2ph9A-5cpcA:
undetectable
2ph9B-5cpcA:
undetectable		 2ph9A-5cpcA:
19.75
2ph9B-5cpcA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD36_0
(GCN4 LEUCINE ZIPPER)		 5cpc SECRETED EFFECTOR
PROTEIN SOPD
(Salmonella
enterica) 		3 / 3 SER A 302
TYR A 296
HIS A 299
 None
 0.81A 2r2vD-5cpcA:
undetectable		 2r2vD-5cpcA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 5cpc SECRETED EFFECTOR
PROTEIN SOPD
(Salmonella
enterica) 		3 / 3 SER A 138
ARG A 144
GLN A 107
 None
 0.83A 2xnrA-5cpcA:
undetectable		 2xnrA-5cpcA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 5cpc SECRETED EFFECTOR
PROTEIN SOPD
(Salmonella
enterica) 		4 / 5 GLY A  35
GLU A 163
HIS A 161
ASP A  38
 None
 1.25A 5c0oH-5cpcA:
undetectable		 5c0oH-5cpcA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB306_0
(WELO5)		 5cpc SECRETED EFFECTOR
PROTEIN SOPD
(Salmonella
enterica) 		3 / 3 GLU A 194
ARG A 191
TYR A 187
 None
 0.58A 5trqB-5cpcA:
undetectable		 5trqB-5cpcA:
21.58