SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cpg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)		 5cpg (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Pseudomonas
aeruginosa) 		5 / 9 PHE A  90
SER A  22
LEU A  31
ALA A  25
GLY A  61
 None
 1.01A 2v0mB-5cpgA:
undetectable		 2v0mB-5cpgA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 5cpg (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Pseudomonas
aeruginosa) 		5 / 12 VAL A  14
LEU A  12
ALA A 138
THR A  81
ILE A 136
 None
None
None
GOL  A 201 ( 4.7A)
None
 1.21A 3a35A-5cpgA:
undetectable		 3a35A-5cpgA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 5cpg (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Pseudomonas
aeruginosa) 		5 / 12 VAL A  14
LEU A  12
ALA A 138
THR A  81
ILE A 136
 None
None
None
GOL  A 201 ( 4.7A)
None
 1.21A 3a3bA-5cpgA:
undetectable		 3a3bA-5cpgA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 5cpg (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Pseudomonas
aeruginosa) 		5 / 11 VAL A 130
VAL A 121
ILE A  72
TYR A  83
LEU A  88
 None
 1.06A 5e4dB-5cpgA:
undetectable		 5e4dB-5cpgA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5cpg (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Pseudomonas
aeruginosa) 		4 / 8 LEU A  88
GLY A  65
ALA A  66
SER A  69
 None
 0.54A 5f1aA-5cpgA:
undetectable		 5f1aA-5cpgA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5cpg (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Pseudomonas
aeruginosa) 		4 / 7 LEU A  88
GLY A  65
ALA A  66
SER A  69
 None
 0.56A 5f1aB-5cpgA:
undetectable		 5f1aB-5cpgA:
14.87