SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cq9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 5cq9 SECRETED EFFECTOR
PROTEIN SOPD2
(Salmonella
enterica) 		5 / 12 LEU A 127
LEU A 124
THR A  85
MET A 101
LEU A 253
 None
 1.11A 1tw4A-5cq9A:
undetectable		 1tw4A-5cq9A:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_A_GJZA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 5cq9 SECRETED EFFECTOR
PROTEIN SOPD2
(Salmonella
enterica) 		4 / 6 LEU A 306
PHE A 229
ILE A 225
THR A 206
 None
 1.12A 3mdrA-5cq9A:
undetectable		 3mdrA-5cq9A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 5cq9 SECRETED EFFECTOR
PROTEIN SOPD2
(Salmonella
enterica) 		4 / 5 TYR A 299
ILE A 298
ASN A 303
ILE A 308
 None
 0.89A 4jtpA-5cq9A:
undetectable		 4jtpA-5cq9A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RMJ_A_NCAA402_0
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-2)		 5cq9 SECRETED EFFECTOR
PROTEIN SOPD2
(Salmonella
enterica) 		4 / 7 ILE A 119
PHE A  99
LEU A  87
LEU A  56
 None
 0.84A 4rmjA-5cq9A:
undetectable		 4rmjA-5cq9A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_A_NOVA2000_1
(DNA GYRASE SUBUNIT B)		 5cq9 SECRETED EFFECTOR
PROTEIN SOPD2
(Salmonella
enterica) 		5 / 12 ASN A 204
GLU A 310
ILE A 308
ILE A 298
SER A 301
 None
 1.11A 4uroA-5cq9A:
undetectable		 4uroA-5cq9A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_B_NOVB2000_1
(DNA GYRASE SUBUNIT B)		 5cq9 SECRETED EFFECTOR
PROTEIN SOPD2
(Salmonella
enterica) 		5 / 12 ASN A 204
GLU A 310
ILE A 308
ILE A 298
SER A 301
 None
 1.14A 4uroB-5cq9A:
undetectable		 4uroB-5cq9A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_B_NOVB2000_1
(DNA GYRASE SUBUNIT B)		 5cq9 SECRETED EFFECTOR
PROTEIN SOPD2
(Salmonella
enterica) 		5 / 12 ASN A 204
ILE A 308
GLN A 228
ILE A 298
SER A 301
 None
 1.40A 4uroB-5cq9A:
undetectable		 4uroB-5cq9A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 5cq9 SECRETED EFFECTOR
PROTEIN SOPD2
(Salmonella
enterica) 		5 / 12 ASN A 204
GLU A 310
ILE A 308
ILE A 298
SER A 301
 None
 1.16A 4uroC-5cq9A:
undetectable		 4uroC-5cq9A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB306_0
(WELO5)		 5cq9 SECRETED EFFECTOR
PROTEIN SOPD2
(Salmonella
enterica) 		3 / 3 GLU A 194
ARG A 191
TYR A 187
 None
 0.58A 5trqB-5cq9A:
undetectable		 5trqB-5cq9A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 5cq9 SECRETED EFFECTOR
PROTEIN SOPD2
(Salmonella
enterica) 		3 / 3 PHE A 223
ARG A 216
GLN A 228
 None
 1.13A 6g1pB-5cq9A:
undetectable		 6g1pB-5cq9A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5cq9 SECRETED EFFECTOR
PROTEIN SOPD2
(Salmonella
enterica) 		4 / 7 ASP A 195
ARG A 196
ASP A 180
GLU A 178
 None
 1.32A 6mn5B-5cq9A:
undetectable		 6mn5B-5cq9A:
13.46