SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cqb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4001_1
(SERUM ALBUMIN)		 5cqb DITRANS,POLYCIS-UNDE
CAPRENYL-DIPHOSPHATE
SYNTHASE
((2E,6E)-FARNESYL-DI
PHOSPHATE SPECIFIC)
(Escherichia
coli) 		4 / 5 ARG A  39
LYS A  33
ALA A  32
GLY A  27
 None
 1.00A 1e7bA-5cqbA:
undetectable		 1e7bA-5cqbA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4001_1
(SERUM ALBUMIN)		 5cqb DITRANS,POLYCIS-UNDE
CAPRENYL-DIPHOSPHATE
SYNTHASE
((2E,6E)-FARNESYL-DI
PHOSPHATE SPECIFIC)
(Escherichia
coli) 		4 / 5 ARG A  39
LYS A  33
ALA A  32
GLY A  27
 None
 1.03A 1e7cA-5cqbA:
undetectable		 1e7cA-5cqbA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 5cqb DITRANS,POLYCIS-UNDE
CAPRENYL-DIPHOSPHATE
SYNTHASE
((2E,6E)-FARNESYL-DI
PHOSPHATE SPECIFIC)
(Escherichia
coli) 		6 / 12 PHE A 224
LEU A 233
HIS A  16
LEU A 191
ILE A 193
ILE A  23
 None
 1.39A 2bxqA-5cqbA:
undetectable		 2bxqA-5cqbA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_F_LFXF0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 5cqb DITRANS,POLYCIS-UNDE
CAPRENYL-DIPHOSPHATE
SYNTHASE
((2E,6E)-FARNESYL-DI
PHOSPHATE SPECIFIC)
(Escherichia
coli) 		4 / 5 SER A  49
ARG A 194
GLY A 196
GLU A 198
 None
 1.23A 3k9fA-5cqbA:
undetectable
3k9fB-5cqbA:
undetectable
3k9fC-5cqbA:
undetectable		 3k9fA-5cqbA:
20.65
3k9fB-5cqbA:
20.65
3k9fC-5cqbA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 5cqb DITRANS,POLYCIS-UNDE
CAPRENYL-DIPHOSPHATE
SYNTHASE
((2E,6E)-FARNESYL-DI
PHOSPHATE SPECIFIC)
(Escherichia
coli) 		4 / 4 GLY A 111
TYR A 145
GLY A 146
ASP A 150
 None
 1.05A 3kl3A-5cqbA:
undetectable		 3kl3A-5cqbA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QT0_A_486A4_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5cqb DITRANS,POLYCIS-UNDE
CAPRENYL-DIPHOSPHATE
SYNTHASE
((2E,6E)-FARNESYL-DI
PHOSPHATE SPECIFIC)
(Escherichia
coli) 		5 / 12 SER A  55
ALA A  58
LEU A 139
ILE A  23
MET A  25
 None
 1.21A 3qt0A-5cqbA:
undetectable		 3qt0A-5cqbA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5cqb DITRANS,POLYCIS-UNDE
CAPRENYL-DIPHOSPHATE
SYNTHASE
((2E,6E)-FARNESYL-DI
PHOSPHATE SPECIFIC)
(Escherichia
coli) 		5 / 11 ILE A 193
ALA A 232
GLY A 231
GLU A 230
GLY A  17
 None
 1.01A 4e47A-5cqbA:
undetectable		 4e47A-5cqbA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5cqb DITRANS,POLYCIS-UNDE
CAPRENYL-DIPHOSPHATE
SYNTHASE
((2E,6E)-FARNESYL-DI
PHOSPHATE SPECIFIC)
(Escherichia
coli) 		5 / 11 ILE A 193
ALA A 232
GLY A 231
GLU A 230
GLY A  17
 None
 1.03A 4e47B-5cqbA:
undetectable		 4e47B-5cqbA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_C_SAMC800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5cqb DITRANS,POLYCIS-UNDE
CAPRENYL-DIPHOSPHATE
SYNTHASE
((2E,6E)-FARNESYL-DI
PHOSPHATE SPECIFIC)
(Escherichia
coli) 		5 / 11 ILE A 193
ALA A 232
GLY A 231
GLU A 230
GLY A  17
 None
 1.03A 4e47C-5cqbA:
undetectable		 4e47C-5cqbA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5cqb DITRANS,POLYCIS-UNDE
CAPRENYL-DIPHOSPHATE
SYNTHASE
((2E,6E)-FARNESYL-DI
PHOSPHATE SPECIFIC)
(Escherichia
coli) 		5 / 11 ILE A 193
ALA A 232
GLY A 231
GLU A 230
GLY A  17
 None
 1.05A 4jdsA-5cqbA:
undetectable		 4jdsA-5cqbA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5cqb DITRANS,POLYCIS-UNDE
CAPRENYL-DIPHOSPHATE
SYNTHASE
((2E,6E)-FARNESYL-DI
PHOSPHATE SPECIFIC)
(Escherichia
coli) 		5 / 11 ILE A 193
ALA A 232
GLY A 231
GLU A 230
GLY A  17
 None
 1.05A 4jdsB-5cqbA:
undetectable		 4jdsB-5cqbA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_C_SAMC401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5cqb DITRANS,POLYCIS-UNDE
CAPRENYL-DIPHOSPHATE
SYNTHASE
((2E,6E)-FARNESYL-DI
PHOSPHATE SPECIFIC)
(Escherichia
coli) 		5 / 11 ILE A 193
ALA A 232
GLY A 231
GLU A 230
GLY A  17
 None
 1.05A 4jdsC-5cqbA:
undetectable		 4jdsC-5cqbA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5cqb DITRANS,POLYCIS-UNDE
CAPRENYL-DIPHOSPHATE
SYNTHASE
((2E,6E)-FARNESYL-DI
PHOSPHATE SPECIFIC)
(Escherichia
coli) 		5 / 12 ILE A 193
ALA A 232
GLY A 231
GLU A 230
GLY A  17
 None
 1.09A 4jlgA-5cqbA:
undetectable		 4jlgA-5cqbA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 5cqb DITRANS,POLYCIS-UNDE
CAPRENYL-DIPHOSPHATE
SYNTHASE
((2E,6E)-FARNESYL-DI
PHOSPHATE SPECIFIC)
(Escherichia
coli) 		3 / 3 GLU A 185
THR A  66
HIS A  20
 None
 0.83A 4q15B-5cqbA:
2.4		 4q15B-5cqbA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5cqb DITRANS,POLYCIS-UNDE
CAPRENYL-DIPHOSPHATE
SYNTHASE
((2E,6E)-FARNESYL-DI
PHOSPHATE SPECIFIC)
(Escherichia
coli) 		5 / 11 ILE A 193
ALA A 232
GLY A 231
GLU A 230
GLY A  17
 None
 1.03A 5ayfA-5cqbA:
undetectable		 5ayfA-5cqbA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 5cqb DITRANS,POLYCIS-UNDE
CAPRENYL-DIPHOSPHATE
SYNTHASE
((2E,6E)-FARNESYL-DI
PHOSPHATE SPECIFIC)
(Escherichia
coli) 		4 / 7 VAL A  54
SER A  55
ALA A  58
VAL A 105
 None
 0.83A 5fpdA-5cqbA:
undetectable		 5fpdA-5cqbA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 5cqb DITRANS,POLYCIS-UNDE
CAPRENYL-DIPHOSPHATE
SYNTHASE
((2E,6E)-FARNESYL-DI
PHOSPHATE SPECIFIC)
(Escherichia
coli) 		4 / 5 LEU A  65
LEU A 137
MET A 183
TYR A  68
 None
 1.45A 5uc3A-5cqbA:
undetectable		 5uc3A-5cqbA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I0Y_A_TRPA3001_0
(23S RIBOSOMAL RNA
TRYPTOPHANASE OPERON
LEADER PEPTIDE)		 5cqb DITRANS,POLYCIS-UNDE
CAPRENYL-DIPHOSPHATE
SYNTHASE
((2E,6E)-FARNESYL-DI
PHOSPHATE SPECIFIC)
(Escherichia
coli) 		3 / 3 TRP A 149
ILE A 151
ASP A 150
 None
 0.82A 6i0y7-5cqbA:
undetectable		 6i0y7-5cqbA:
8.11