SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cqf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 GLY A 417
LEU A  74
VAL A 118
ASN A 394
ARG A 415
 None
 1.06A 1dfoA-5cqfA:
undetectable		 1dfoA-5cqfA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 GLY A 417
LEU A  74
VAL A 118
ASN A 394
ARG A 415
 None
 1.05A 1dfoB-5cqfA:
undetectable		 1dfoB-5cqfA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 GLY A 417
LEU A  74
VAL A 118
ASN A 394
ARG A 415
 None
 1.06A 1dfoC-5cqfA:
undetectable		 1dfoC-5cqfA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 GLY A 417
LEU A  74
VAL A 118
ASN A 394
ARG A 415
 None
 1.05A 1dfoD-5cqfA:
undetectable		 1dfoD-5cqfA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4004_1
(SERUM ALBUMIN)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 4 VAL A 217
PHE A 238
SER A 231
VAL A 229
 None
 1.27A 1e7cA-5cqfA:
undetectable		 1e7cA-5cqfA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 GLY A 417
LEU A  74
VAL A 118
ASN A 394
ARG A 415
 None
 1.08A 1eqbA-5cqfA:
undetectable		 1eqbA-5cqfA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 GLY A 417
LEU A  74
VAL A 118
ASN A 394
ARG A 415
 None
 1.07A 1eqbB-5cqfA:
undetectable		 1eqbB-5cqfA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 GLY A 417
LEU A  74
VAL A 118
ASN A 394
ARG A 415
 None
 1.07A 1eqbC-5cqfA:
undetectable		 1eqbC-5cqfA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 GLY A 417
LEU A  74
VAL A 118
ASN A 394
ARG A 415
 None
 1.07A 1eqbD-5cqfA:
undetectable		 1eqbD-5cqfA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_0
(HYPOTHETICAL PROTEIN
RV2118C)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 GLY A  17
GLY A  19
ALA A  24
LEU A  25
VAL A 132
 None
 0.83A 1i9gA-5cqfA:
4.0		 1i9gA-5cqfA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 12 ILE A  23
ALA A  24
ALA A  21
PHE A 409
LEU A  74
ALA A 413
 None
 1.38A 1xlsD-5cqfA:
undetectable		 1xlsD-5cqfA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA501_0
(FERROCHELATASE)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 LEU A 357
LEU A 358
LEU A 373
ILE A  16
THR A 383
 None
 1.32A 2qd3A-5cqfA:
undetectable		 2qd3A-5cqfA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 GLY A  17
GLY A  19
ALA A  24
LEU A  25
ALA A  49
 None
 0.81A 2yvlA-5cqfA:
2.7		 2yvlA-5cqfA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 GLY A  17
GLY A  19
ALA A  24
LEU A  25
ALA A  49
 None
 0.80A 2yvlB-5cqfA:
2.2		 2yvlB-5cqfA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 GLY A  17
GLY A  19
ALA A  24
LEU A  25
ALA A  49
 None
 0.80A 2yvlD-5cqfA:
3.2		 2yvlD-5cqfA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 GLY A  17
GLY A  19
ALA A  24
LEU A  25
ASN A 394
 None
 1.07A 2zulA-5cqfA:
2.1		 2zulA-5cqfA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 TYR A 349
GLU A 215
ASP A 285
 None
 0.89A 3bxoB-5cqfA:
2.3		 3bxoB-5cqfA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 GLY A  17
GLY A  19
ALA A  24
LEU A  25
ASN A 394
 None
 1.03A 3dmhA-5cqfA:
undetectable		 3dmhA-5cqfA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 10 ILE A 419
ALA A 416
LEU A  25
ALA A  24
ILE A 375
 None
 1.02A 3falC-5cqfA:
undetectable		 3falC-5cqfA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 ILE A 419
ALA A 416
LEU A  25
ALA A  24
ILE A 375
 None
 1.00A 3fc6A-5cqfA:
undetectable		 3fc6A-5cqfA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_1
(PROTEIN S100-A4)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 GLU A 424
LEU A  42
ASP A  41
 None
 0.43A 3ko0A-5cqfA:
undetectable		 3ko0A-5cqfA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_2
(PROTEIN S100-A4)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 GLU A 424
LEU A  42
ASP A  41
 None
 0.43A 3ko0T-5cqfA:
undetectable		 3ko0T-5cqfA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 HIS A  56
GLY A  17
GLY A  19
PHE A 128
LEU A  47
 None
 1.04A 3vywB-5cqfA:
2.5		 3vywB-5cqfA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 HIS A  56
GLY A  17
GLY A  19
PHE A 128
LEU A  47
 None
 1.03A 3vywD-5cqfA:
undetectable		 3vywD-5cqfA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 VAL A 162
TYR A  46
GLY A 417
ALA A 420
LEU A 423
 None
 1.11A 4rrxA-5cqfA:
undetectable		 4rrxA-5cqfA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 VAL A 162
TYR A  46
GLY A 417
ALA A 420
LEU A 423
 None
 1.11A 4rrxB-5cqfA:
undetectable		 4rrxB-5cqfA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CVT_B_ACTB200_0
(N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 ASN A 263
ALA A 265
ARG A 269
 None
 0.49A 5cvtB-5cqfA:
3.4		 5cvtB-5cqfA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 VAL A 344
ALA A 213
SER A 216
PHE A 238
LEU A 305
 None
IOD  A 507 (-3.6A)
None
None
None
 1.45A 5m54B-5cqfA:
2.3		 5m54B-5cqfA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 THR A 319
HIS A 318
ALA A 320
ASP A 321
 None
 1.18A 5mfxA-5cqfA:
2.6		 5mfxA-5cqfA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 5 ARG A 223
LEU A 200
PHE A 196
LEU A 193
PHE A 189
 None
 1.44A 5x19C-5cqfA:
undetectable
5x19J-5cqfA:
undetectable		 5x19C-5cqfA:
21.84
5x19J-5cqfA:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 ARG A 223
LEU A 200
PHE A 196
LEU A 193
 None
 1.04A 5x1bP-5cqfA:
undetectable		 5x1bP-5cqfA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 9 ALA A 416
ALA A  21
VAL A 162
SER A 164
GLY A 395
 None
 1.26A 6bklA-5cqfA:
undetectable
6bklB-5cqfA:
undetectable
6bklC-5cqfA:
undetectable
6bklD-5cqfA:
undetectable		 6bklA-5cqfA:
4.33
6bklB-5cqfA:
4.33
6bklC-5cqfA:
4.33
6bklD-5cqfA:
4.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 5cqf L-LYSINE
6-MONOOXYGENASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 SER A 164
VAL A 162
ARG A 418
ILE A 419
ASP A 378
 None
None
IOD  A 503 ( 4.9A)
None
None
 1.46A 6bxnA-5cqfA:
2.9		 6bxnA-5cqfA:
22.54