SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cr9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		5 / 12 LEU A 180
ASP A 130
LEU A  63
LEU A 133
PHE A  54
 None
 1.10A 1d4fA-5cr9A:
3.3		 1d4fA-5cr9A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_2
(HIV-II PROTEASE)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		5 / 9 ALA A  85
ILE A 124
VAL A 132
GLY A 134
ILE A 119
 None
 0.74A 1hshB-5cr9A:
undetectable		 1hshB-5cr9A:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IA0_B_TXLB502_1
(TUBULIN BETA CHAIN)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		5 / 12 VAL A 278
ASP A 137
HIS A 116
SER A  66
PRO A 316
 None
None
MN  A 501 ( 3.4A)
None
None
 1.41A 1ia0B-5cr9A:
2.3		 1ia0B-5cr9A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUB_B_TXLB501_1
(TUBULIN)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		5 / 12 VAL A 278
ASP A 137
HIS A 116
SER A  66
PRO A 316
 None
None
MN  A 501 ( 3.4A)
None
None
 1.41A 1tubB-5cr9A:
1.7		 1tubB-5cr9A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		3 / 3 ARG A 183
ARG A 186
ILE A 174
 None
 0.79A 1uobA-5cr9A:
undetectable		 1uobA-5cr9A:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_1
(HIV-1 PROTEASE)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		5 / 12 GLY A  86
ALA A  85
ILE A 124
GLY A 134
ILE A 119
 None
 0.75A 2hs1A-5cr9A:
undetectable		 2hs1A-5cr9A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		5 / 12 GLY A  86
ALA A  85
VAL A 132
GLY A 134
ILE A 119
 None
 0.75A 2rkgB-5cr9A:
undetectable		 2rkgB-5cr9A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_A_ECNA1409_1
(CYTOCHROME P450 130)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		5 / 12 LEU A 131
PRO A  58
PRO A  57
GLY A 178
LEU A 133
 None
 0.91A 2uvnA-5cr9A:
undetectable		 2uvnA-5cr9A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		5 / 12 GLN A 154
MET A  72
PHE A 181
VAL A  81
ILE A  61
 None
 1.29A 3em0A-5cr9A:
undetectable		 3em0A-5cr9A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		5 / 12 LEU A 180
ASP A 130
LEU A  63
LEU A 133
PHE A  54
 None
 1.08A 3g1uC-5cr9A:
3.7		 3g1uC-5cr9A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		5 / 12 LEU A 180
ASP A 130
LEU A  63
LEU A 133
PHE A  54
 None
 1.13A 3g1uD-5cr9A:
undetectable		 3g1uD-5cr9A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		5 / 12 LEU A 180
ASP A 130
LEU A  63
LEU A 133
PHE A  54
 None
 1.10A 3glqA-5cr9A:
undetectable		 3glqA-5cr9A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		5 / 12 LEU A 180
ASP A 130
LEU A  63
LEU A 133
PHE A  54
 None
 1.12A 3glqB-5cr9A:
undetectable		 3glqB-5cr9A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		5 / 12 LEU A 180
ASP A 130
LEU A  63
LEU A 133
PHE A  54
 None
 1.13A 3n58A-5cr9A:
undetectable		 3n58A-5cr9A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		5 / 12 LEU A 180
ASP A 130
LEU A  63
LEU A 133
PHE A  54
 None
 1.10A 3n58D-5cr9A:
undetectable		 3n58D-5cr9A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		5 / 9 GLY A  86
ALA A  85
ILE A 124
GLY A 134
ILE A 119
 None
 0.90A 3nu4B-5cr9A:
undetectable		 3nu4B-5cr9A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OI8_A_ADNA2_1
(UNCHARACTERIZED
PROTEIN)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		4 / 6 ILE A  45
ASN A 150
PRO A  58
LEU A 180
 None
 1.16A 3oi8A-5cr9A:
undetectable		 3oi8A-5cr9A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_1
(PROTEASE)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		5 / 12 LEU A 307
ALA A 216
ASP A 271
GLY A 245
THR A 331
 None
 1.05A 4njuA-5cr9A:
undetectable		 4njuA-5cr9A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		4 / 7 LEU A 276
THR A 314
ILE A 328
LEU A 325
 None
 1.00A 5fxtA-5cr9A:
undetectable		 5fxtA-5cr9A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		4 / 6 VAL A 278
LEU A  64
ARG A  84
ILE A  62
 None
 0.91A 5jw1A-5cr9A:
undetectable		 5jw1A-5cr9A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_1
(PROTEASE)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		5 / 12 GLY A  86
ALA A  85
ILE A 124
VAL A 132
GLY A 134
 None
 0.82A 5t8hA-5cr9A:
undetectable		 5t8hA-5cr9A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_1
(PROTEASE)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		5 / 12 GLY A  86
ALA A  85
VAL A 132
GLY A 134
ILE A 119
 None
 0.83A 5t8hA-5cr9A:
undetectable		 5t8hA-5cr9A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_1
(PROTEASE)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		5 / 12 GLY A  86
ALA A  85
ILE A  62
GLY A 134
ILE A 119
 None
 1.04A 6dh3B-5cr9A:
undetectable		 6dh3B-5cr9A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_1
(-)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		5 / 12 LEU A 180
ASP A 130
LEU A  63
LEU A 133
PHE A  54
 None
 1.12A 6gbnC-5cr9A:
undetectable		 6gbnC-5cr9A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 5cr9 ABC-TYPE
FE3+-HYDROXAMATE
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Saccharomonospor
a
viridis) 		4 / 7 ILE A 328
GLN A 240
GLU A 315
VAL A 274
 None
 0.95A 6j20A-5cr9A:
undetectable		 6j20A-5cr9A:
21.83