SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5crc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E7B_B_HLTB4003_1 (SERUM ALBUMIN)	5crc	SDEA (Legionella pneumophila)	4 / 6	VAL A 144 GLY A 145 ALA A 129 LEU A 133	VAL A 144 ( 0.6A) GLY A 145 ( 0.0A) ALA A 129 ( 0.0A) LEU A 133 ( 0.6A)	0.78A	1e7bB-5crcA: undetectable	1e7bB-5crcA: 13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YAJ_J_BEZJ5041_0 (CES1 PROTEIN)	5crc	SDEA (Legionella pneumophila)	4 / 4	GLY A 83 SER A 86 ILE A 66 HIS A 64	GLY A 83 ( 0.0A) SER A 86 ( 0.0A) ILE A 66 ( 0.7A) HIS A 64 ( 1.0A)	1.25A	1yajJ-5crcA: undetectable	1yajJ-5crcA: 15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_B_DSFB319_1 (GLR4197 PROTEIN)	5crc	SDEA (Legionella pneumophila)	5 / 9	TYR A 90 ILE A 32 ILE A 93 VAL A 52 ILE A 39	TYR A 90 ( 1.3A) ILE A 32 ( 0.4A) ILE A 93 ( 0.4A) VAL A 52 ( 0.6A) ILE A 39 ( 0.5A)	1.24A	3p4wB-5crcA: undetectable	3p4wB-5crcA: 19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QEL_B_QELB1_1 (NMDA GLUTAMATE RECEPTOR SUBUNIT GLUTAMATE [NMDA] RECEPTOR SUBUNIT EPSILON-2)	5crc	SDEA (Legionella pneumophila)	5 / 11	TYR A 76 THR A 103 LEU A 78 ALA A 96 THR A 54	TYR A 76 ( 1.3A) THR A 103 ( 0.8A) LEU A 78 ( 0.6A) ALA A 96 ( 0.0A) THR A 54 ( 0.8A)	1.25A	3qelA-5crcA: undetectable 3qelB-5crcA: undetectable	3qelA-5crcA: 21.09 3qelB-5crcA: 23.28

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1E7B_B_HLTB4003_1","SERUM ALBUMIN","5crc","SDEA","Legionella pneumophila",4,"VAL A 144;GLY A 145;ALA A 129;LEU A 133","VAL A 144 ( 0.6A);GLY A 145 ( 0.0A);ALA A 129 ( 0.0A);LEU A 133 ( 0.6A)","0.78A","1e7bB-5crcA:undetectable","1e7bB-5crcA:13.60"],["1YAJ_J_BEZJ5041_0","CES1 PROTEIN","5crc","SDEA","Legionella pneumophila",4,"GLY A  83;SER A  86;ILE A  66;HIS A  64","GLY A  83 ( 0.0A);SER A  86 ( 0.0A);ILE A  66 ( 0.7A);HIS A  64 ( 1.0A)","1.25A","1yajJ-5crcA:undetectable","1yajJ-5crcA:15.17"],["3P4W_B_DSFB319_1","GLR4197 PROTEIN","5crc","SDEA","Legionella pneumophila",5,"TYR A  90;ILE A  32;ILE A  93;VAL A  52;ILE A  39","TYR A  90 ( 1.3A);ILE A  32 ( 0.4A);ILE A  93 ( 0.4A);VAL A  52 ( 0.6A);ILE A  39 ( 0.5A)","1.24A","3p4wB-5crcA:undetectable","3p4wB-5crcA:19.70"],["3QEL_B_QELB1_1","NMDA GLUTAMATE RECEPTOR SUBUNIT;GLUTAMATE [NMDA] RECEPTOR SUBUNIT EPSILON-2","5crc","SDEA","Legionella pneumophila",5,"TYR A  76;THR A 103;LEU A  78;ALA A  96;THR A  54","TYR A  76 ( 1.3A);THR A 103 ( 0.8A);LEU A  78 ( 0.6A);ALA A  96 ( 0.0A);THR A  54 ( 0.8A)","1.25A","3qelA-5crcA:undetectable;3qelB-5crcA:undetectable","3qelA-5crcA:21.09;3qelB-5crcA:23.28"]]