SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5crl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1H9Z_A_RWFA3001_1 (SERUM ALBUMIN)	5crl	MERCURIC RESISTANCE OPERON REGULATORY PROTEIN (Pseudomonas aeruginosa)	5 / 11	PHE A 56 ALA A 60 LEU A 73 SER A 87 ALA A 89	None	1.15A	1h9zA-5crlA: 2.1	1h9zA-5crlA: 12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F9W_A_PAUA6002_0 (PANTOTHENATE KINASE)	5crl	MERCURIC RESISTANCE OPERON REGULATORY PROTEIN (Pseudomonas aeruginosa)	4 / 8	ARG A 55 GLY A 18 THR A 23 ILE A 24	None	0.95A	2f9wA-5crlA: undetectable 2f9wB-5crlA: undetectable	2f9wA-5crlA: 20.44 2f9wB-5crlA: 20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZBD_A_TRPA501_0 (FLAVIN-DEPENDENT L-TRYPTOPHAN OXIDASE VIOA)	5crl	MERCURIC RESISTANCE OPERON REGULATORY PROTEIN (Pseudomonas aeruginosa)	5 / 10	ARG A 25 TYR A 46 LEU A 33 ASP A 50 VAL A 54	None	1.22A	5zbdA-5crlA: undetectable	5zbdA-5crlA: 16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZBD_B_TRPB501_0 (FLAVIN-DEPENDENT L-TRYPTOPHAN OXIDASE VIOA)	5crl	MERCURIC RESISTANCE OPERON REGULATORY PROTEIN (Pseudomonas aeruginosa)	5 / 10	ARG A 25 TYR A 46 LEU A 33 ASP A 50 VAL A 54	None	1.21A	5zbdB-5crlA: undetectable	5zbdB-5crlA: 16.37

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1H9Z_A_RWFA3001_1","SERUM ALBUMIN","5crl","MERCURIC RESISTANCE OPERON REGULATORY PROTEIN","Pseudomonas aeruginosa",5,"PHE A  56;ALA A  60;LEU A  73;SER A  87;ALA A  89","None","1.15A","1h9zA-5crlA:2.1","1h9zA-5crlA:12.99"],["2F9W_A_PAUA6002_0","PANTOTHENATE KINASE","5crl","MERCURIC RESISTANCE OPERON REGULATORY PROTEIN","Pseudomonas aeruginosa",4,"ARG A  55;GLY A  18;THR A  23;ILE A  24","None","0.95A","2f9wA-5crlA:undetectable;2f9wB-5crlA:undetectable","2f9wA-5crlA:20.44;2f9wB-5crlA:20.44"],["5ZBD_A_TRPA501_0","FLAVIN-DEPENDENT L-TRYPTOPHAN OXIDASE VIOA","5crl","MERCURIC RESISTANCE OPERON REGULATORY PROTEIN","Pseudomonas aeruginosa",5,"ARG A  25;TYR A  46;LEU A  33;ASP A  50;VAL A  54","None","1.22A","5zbdA-5crlA:undetectable","5zbdA-5crlA:16.37"],["5ZBD_B_TRPB501_0","FLAVIN-DEPENDENT L-TRYPTOPHAN OXIDASE VIOA","5crl","MERCURIC RESISTANCE OPERON REGULATORY PROTEIN","Pseudomonas aeruginosa",5,"ARG A  25;TYR A  46;LEU A  33;ASP A  50;VAL A  54","None","1.21A","5zbdB-5crlA:undetectable","5zbdB-5crlA:16.37"]]