SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5csu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		6 / 12 SER A 134
TYR A 136
GLN A 336
HIS A 374
GLU A 420
HIS A 472
 GLC  A 605 ( 2.8A)
HMC  A 606 ( 4.0A)
AGL  A 607 ( 3.6A)
AGL  A 607 ( 3.8A)
AGL  A 607 ( 2.7A)
HMC  A 606 ( 3.8A)
 0.84A 1eswA-5csuA:
48.3		 1eswA-5csuA:
38.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		8 / 12 SER A 134
TYR A 136
GLU A 420
HIS A 472
ASP A 473
ASN A 537
PRO A 539
TRP A 546
 GLC  A 605 ( 2.8A)
HMC  A 606 ( 4.0A)
AGL  A 607 ( 2.7A)
HMC  A 606 ( 3.8A)
HMC  A 606 ( 2.8A)
GLC  A 605 ( 3.7A)
GLC  A 605 ( 3.6A)
None
 0.48A 1eswA-5csuA:
48.3		 1eswA-5csuA:
38.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		6 / 12 SER A 134
TYR A 136
HIS A 374
GLU A 420
HIS A 472
TRP A 546
 GLC  A 605 ( 2.8A)
HMC  A 606 ( 4.0A)
AGL  A 607 ( 3.8A)
AGL  A 607 ( 2.7A)
HMC  A 606 ( 3.8A)
None
 0.71A 1eswA-5csuA:
48.3		 1eswA-5csuA:
38.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		6 / 12 TYR A 136
GLN A 336
TRP A 338
HIS A 374
GLU A 420
HIS A 472
 HMC  A 606 ( 4.0A)
AGL  A 607 ( 3.6A)
HMC  A 606 ( 3.6A)
AGL  A 607 ( 3.8A)
AGL  A 607 ( 2.7A)
HMC  A 606 ( 3.8A)
 0.83A 1eswA-5csuA:
48.3		 1eswA-5csuA:
38.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		5 / 12 TYR A 136
TRP A 338
GLU A 420
HIS A 472
ASP A 473
 HMC  A 606 ( 4.0A)
HMC  A 606 ( 3.6A)
AGL  A 607 ( 2.7A)
HMC  A 606 ( 3.8A)
HMC  A 606 ( 2.8A)
 0.92A 1eswA-5csuA:
48.3		 1eswA-5csuA:
38.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_B_STIB202_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		4 / 7 VAL A 443
ILE A 477
ARG A 371
LEU A 566
 None
None
HMC  A 606 ( 3.7A)
None
 0.96A 1iepB-5csuA:
undetectable		 1iepB-5csuA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA6_0
(MINI-GRAMICIDIN A)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		3 / 3 ALA A 383
VAL A 326
TRP A 338
 None
None
HMC  A 606 ( 3.6A)
 0.82A 1kqeA-5csuA:
undetectable
1kqeE-5csuA:
undetectable		 1kqeA-5csuA:
4.44
1kqeE-5csuA:
4.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_B_DVAB6_0
(MINI-GRAMICIDIN A)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		3 / 3 ALA A 383
VAL A 326
TRP A 338
 None
None
HMC  A 606 ( 3.6A)
 0.82A 1kqeB-5csuA:
undetectable
1kqeD-5csuA:
undetectable		 1kqeB-5csuA:
4.44
1kqeD-5csuA:
4.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_D_DVAD6_0
(MINI-GRAMICIDIN A)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		3 / 3 TRP A 338
ALA A 383
VAL A 326
 HMC  A 606 ( 3.6A)
None
None
 0.81A 1kqeB-5csuA:
undetectable
1kqeD-5csuA:
undetectable		 1kqeB-5csuA:
4.44
1kqeD-5csuA:
4.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_E_DVAE6_0
(MINI-GRAMICIDIN A)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		3 / 3 TRP A 338
ALA A 383
VAL A 326
 HMC  A 606 ( 3.6A)
None
None
 0.79A 1kqeA-5csuA:
undetectable
1kqeE-5csuA:
undetectable		 1kqeA-5csuA:
4.44
1kqeE-5csuA:
4.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_C_TPFC2471_1
(CYTOCHROME P450 121)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		4 / 8 THR A 146
ASN A 142
PHE A 265
ALA A 221
 None
 0.97A 2ij7C-5csuA:
undetectable		 2ij7C-5csuA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O02_B_BEZB802_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		4 / 4 ILE A 418
MET A 441
GLN A 465
ARG A 433
 None
 1.42A 2o02B-5csuA:
0.0		 2o02B-5csuA:
17.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OWC_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		10 / 11 SER A 134
TYR A 136
GLN A 336
TRP A 338
ASP A 373
HIS A 472
ASP A 473
ASN A 537
PRO A 539
TRP A 546
 GLC  A 605 ( 2.8A)
HMC  A 606 ( 4.0A)
AGL  A 607 ( 3.6A)
HMC  A 606 ( 3.6A)
HMC  A 606 ( 3.0A)
HMC  A 606 ( 3.8A)
HMC  A 606 ( 2.8A)
GLC  A 605 ( 3.7A)
GLC  A 605 ( 3.6A)
None
 0.71A 2owcA-5csuA:
49.3		 2owcA-5csuA:
38.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		10 / 11 SER A 134
TYR A 136
GLN A 336
TRP A 338
ASP A 373
HIS A 472
ASP A 473
ASN A 537
PRO A 539
TRP A 546
 GLC  A 605 ( 2.8A)
HMC  A 606 ( 4.0A)
AGL  A 607 ( 3.6A)
HMC  A 606 ( 3.6A)
HMC  A 606 ( 3.0A)
HMC  A 606 ( 3.8A)
HMC  A 606 ( 2.8A)
GLC  A 605 ( 3.7A)
GLC  A 605 ( 3.6A)
None
 0.52A 2owwA-5csuA:
50.0		 2owwA-5csuA:
38.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_B_EV1B1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		4 / 8 LEU A  88
VAL A 279
ILE A 290
TYR A 367
 None
 0.94A 2weyB-5csuA:
undetectable		 2weyB-5csuA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		3 / 3 ARG A 246
ASP A 140
ASN A 308
 None
 0.80A 2zzmA-5csuA:
undetectable		 2zzmA-5csuA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		5 / 12 ARG A 371
ASP A 373
GLU A 420
HIS A 472
ASP A 473
 HMC  A 606 ( 3.7A)
HMC  A 606 ( 3.0A)
AGL  A 607 ( 2.7A)
HMC  A 606 ( 3.8A)
HMC  A 606 ( 2.8A)
 0.89A 3aicA-5csuA:
5.5		 3aicA-5csuA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		5 / 12 ARG A 371
ASP A 373
GLU A 420
HIS A 472
ASP A 473
 HMC  A 606 ( 3.7A)
HMC  A 606 ( 3.0A)
AGL  A 607 ( 2.7A)
HMC  A 606 ( 3.8A)
HMC  A 606 ( 2.8A)
 0.89A 3aicE-5csuA:
5.5		 3aicE-5csuA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		5 / 12 ARG A 371
ASP A 373
GLU A 420
HIS A 472
ASP A 473
 HMC  A 606 ( 3.7A)
HMC  A 606 ( 3.0A)
AGL  A 607 ( 2.7A)
HMC  A 606 ( 3.8A)
HMC  A 606 ( 2.8A)
 0.86A 3aicF-5csuA:
5.2		 3aicF-5csuA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		5 / 12 ARG A 371
ASP A 373
GLU A 420
HIS A 472
ASP A 473
 HMC  A 606 ( 3.7A)
HMC  A 606 ( 3.0A)
AGL  A 607 ( 2.7A)
HMC  A 606 ( 3.8A)
HMC  A 606 ( 2.8A)
 0.94A 3aicH-5csuA:
5.4		 3aicH-5csuA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		4 / 7 TRP A 338
SER A 324
VAL A 384
TRP A 382
 HMC  A 606 ( 3.6A)
None
None
None
 1.38A 3dqtA-5csuA:
undetectable
3dqtB-5csuA:
undetectable		 3dqtA-5csuA:
22.11
3dqtB-5csuA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		4 / 4 ILE A 372
GLN A 122
ILE A 415
LEU A 124
 None
None
EDO  A 602 ( 3.7A)
None
 1.02A 3dzyD-5csuA:
undetectable		 3dzyD-5csuA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		4 / 7 SER A 324
VAL A 384
TRP A 382
TRP A 338
 None
None
None
HMC  A 606 ( 3.6A)
 1.27A 3n5tA-5csuA:
undetectable
3n5tB-5csuA:
undetectable		 3n5tA-5csuA:
21.80
3n5tB-5csuA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		4 / 7 TRP A 338
SER A 324
VAL A 384
TRP A 382
 HMC  A 606 ( 3.6A)
None
None
None
 1.28A 3n61A-5csuA:
1.0
3n61B-5csuA:
undetectable		 3n61A-5csuA:
21.72
3n61B-5csuA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A2000_1
(P38A)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		5 / 12 ILE A 415
VAL A 120
ILE A 521
ILE A 417
ALA A 363
 EDO  A 602 ( 3.7A)
None
None
None
EDO  A 602 ( 4.6A)
 0.96A 3ohtA-5csuA:
undetectable
3ohtB-5csuA:
undetectable		 3ohtA-5csuA:
23.14
3ohtB-5csuA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		5 / 12 ARG A 359
GLY A 292
PRO A 135
ALA A 137
GLY A 138
 None
None
None
GLC  A 605 ( 4.1A)
None
 1.17A 3v3oB-5csuA:
undetectable		 3v3oB-5csuA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		5 / 11 ARG A 359
GLY A 292
PRO A 135
ALA A 137
GLY A 138
 None
None
None
GLC  A 605 ( 4.1A)
None
 1.09A 4a6nA-5csuA:
1.0		 4a6nA-5csuA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_B_ZPCB1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		5 / 12 ILE A 290
GLU A 105
GLU A 104
HIS A 114
PHE A 107
 None
 1.42A 4a97A-5csuA:
undetectable
4a97B-5csuA:
undetectable		 4a97A-5csuA:
19.40
4a97B-5csuA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_G_ZPCG1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		5 / 12 ILE A 290
GLU A 105
GLU A 104
HIS A 114
PHE A 107
 None
 1.37A 4a97F-5csuA:
0.6
4a97G-5csuA:
0.0		 4a97F-5csuA:
19.40
4a97G-5csuA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		4 / 7 TRP A 338
SER A 324
VAL A 384
TRP A 382
 HMC  A 606 ( 3.6A)
None
None
None
 1.33A 4k5jA-5csuA:
1.0
4k5jB-5csuA:
undetectable		 4k5jA-5csuA:
21.80
4k5jB-5csuA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		5 / 11 SER A  92
LEU A  87
ASP A 526
LEU A 530
LEU A  88
 None
 1.43A 4or0A-5csuA:
undetectable		 4or0A-5csuA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		3 / 3 GLU A 420
ARG A 371
GLN A 336
 AGL  A 607 ( 2.7A)
HMC  A 606 ( 3.7A)
AGL  A 607 ( 3.6A)
 0.97A 4rtbA-5csuA:
4.3		 4rtbA-5csuA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		4 / 7 TRP A 338
SER A 324
VAL A 384
TRP A 382
 HMC  A 606 ( 3.6A)
None
None
None
 1.32A 5adlA-5csuA:
undetectable
5adlB-5csuA:
undetectable		 5adlA-5csuA:
21.80
5adlB-5csuA:
21.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		12 / 12 ASP A 329
LEU A 330
GLN A 336
TRP A 338
ARG A 371
ASP A 373
GLU A 420
GLY A 423
PHE A 446
HIS A 456
HIS A 472
ASP A 473
 GLC  A 608 ( 3.5A)
BGC  A 609 ( 3.6A)
AGL  A 607 ( 3.6A)
HMC  A 606 ( 3.6A)
HMC  A 606 ( 3.7A)
HMC  A 606 ( 3.0A)
AGL  A 607 ( 2.7A)
GLC  A 608 ( 3.6A)
BGC  A 609 ( 4.1A)
BGC  A 609 ( 4.3A)
HMC  A 606 ( 3.8A)
HMC  A 606 ( 2.8A)
 0.31A 5csyB-5csuA:
60.3		 5csyB-5csuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		5 / 5 TYR A 136
PHE A 331
HIS A 374
LEU A 422
PRO A 539
 HMC  A 606 ( 4.0A)
GLC  A 608 ( 4.7A)
AGL  A 607 ( 3.8A)
GLC  A 608 ( 3.8A)
GLC  A 605 ( 3.6A)
 0.13A 5csyB-5csuA:
60.3		 5csyB-5csuA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		4 / 7 TRP A 338
SER A 324
VAL A 384
TRP A 382
 HMC  A 606 ( 3.6A)
None
None
None
 1.32A 5fj3A-5csuA:
undetectable
5fj3B-5csuA:
undetectable		 5fj3A-5csuA:
21.80
5fj3B-5csuA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_E_SAME301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		5 / 12 ASP A 140
ALA A 141
PRO A 320
SER A 302
TYR A 300
 None
 1.10A 5hfjE-5csuA:
undetectable		 5hfjE-5csuA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JM4_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		4 / 5 ILE A 418
MET A 441
GLN A 465
ARG A 433
 None
 1.47A 5jm4A-5csuA:
undetectable		 5jm4A-5csuA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		3 / 3 GLY A 335
TRP A 382
VAL A 384
 None
 0.77A 5vuoB-5csuA:
undetectable		 5vuoB-5csuA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		4 / 7 TRP A 338
SER A 324
VAL A 384
TRP A 382
 HMC  A 606 ( 3.6A)
None
None
None
 1.32A 5vv7A-5csuA:
0.5
5vv7B-5csuA:
undetectable		 5vv7A-5csuA:
21.80
5vv7B-5csuA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		4 / 7 TRP A 338
SER A 324
VAL A 384
TRP A 382
 HMC  A 606 ( 3.6A)
None
None
None
 1.37A 5vvnA-5csuA:
undetectable
5vvnB-5csuA:
undetectable		 5vvnA-5csuA:
21.80
5vvnB-5csuA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		4 / 7 SER A 324
VAL A 384
TRP A 382
TRP A 338
 None
None
None
HMC  A 606 ( 3.6A)
 1.38A 6av6A-5csuA:
undetectable
6av6B-5csuA:
0.0		 6av6A-5csuA:
8.35
6av6B-5csuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		4 / 7 TRP A 338
SER A 324
VAL A 384
TRP A 382
 HMC  A 606 ( 3.6A)
None
None
None
 1.36A 6av6C-5csuA:
undetectable
6av6D-5csuA:
undetectable		 6av6C-5csuA:
8.35
6av6D-5csuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		4 / 7 SER A 324
VAL A 384
TRP A 382
TRP A 338
 None
None
None
HMC  A 606 ( 3.6A)
 1.44A 6av7A-5csuA:
undetectable
6av7B-5csuA:
0.0		 6av7A-5csuA:
8.35
6av7B-5csuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		3 / 3 ARG A 376
PHE A 375
GLY A 377
 None
 0.67A 6fgdA-5csuA:
undetectable		 6fgdA-5csuA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		4 / 4 ILE A 418
MET A 441
GLN A 465
ARG A 433
 None
 1.47A 6fn9B-5csuA:
0.0		 6fn9B-5csuA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC
(Arabidopsis
thaliana) 		3 / 3 ASP A 373
SER A 340
SER A 324
 HMC  A 606 ( 3.0A)
None
None
 0.65A 6mxtA-5csuA:
undetectable		 6mxtA-5csuA:
21.21